Tobias L Lenz
Tobias L Lenz
Professor for Evolutionary Immunogenomics, Institute of Zoology, University of Hamburg
Verified email at - Homepage
Cited by
Cited by
Genomewide Association Study of Severe Covid-19 with Respiratory Failure
D Ellinghaus, F Degenhardt, L Bujanda, M Buti, A Albillos, P Invernizzi, ...
New England Journal of Medicine 383, 1522-1534, 2020
Genome analysis reveals insights into physiology and longevity of the Brandt’s bat Myotis brandtii
I Seim, X Fang, Z Xiong, AV Lobanov, Z Huang, S Ma, Y Feng, ...
Nature Communications 4, 2212, 2013
Rapid and adaptive evolution of MHC genes under parasite selection in experimental vertebrate populations
C Eizaguirre, TL Lenz, M Kalbe, M Milinski
Nature Communications 3, 621, 2012
MHC‐based mate choice combines good genes and maintenance of MHC polymorphism
C Eizaguirre, SE Yeates, TL Lenz, M Kalbe, M Milinski
Molecular Ecology 18 (15), 3316-3329, 2009
Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk
X Hu, AJ Deutsch, TL Lenz, S Onengut-Gumuscu, B Han, WM Chen, ...
Nature Genetics 47 (8), 898-905, 2015
Divergent selection on locally adapted major histocompatibility complex immune genes experimentally proven in the field
C Eizaguirre, TL Lenz, M Kalbe, M Milinski
Ecology Letters 15 (7), 723-731, 2012
Simple approach to reduce PCR artefact formation leads to reliable genotyping of MHC and other highly polymorphic loci—Implications for evolutionary analysis
TL Lenz, S Becker
Gene 427 (1), 117-123, 2008
Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases
TL Lenz, AJ Deutsch, B Han, X Hu, Y Okada, S Eyre, M Knapp, ...
Nature Genetics 47 (9), 963-1099, 2015
Parasite diversity, patterns of MHC II variation and olfactory based mate choice in diverging three-spined stickleback ecotypes
C Eizaguirre, TL Lenz, RD Sommerfeld, C Harrod, M Kalbe, M Milinski
Evolutionary Ecology 25 (3), 605-622, 2011
Genomics of Divergence along a Continuum of Parapatric Population Differentiation
PGD Feulner, FJJ Chain, M Panchal, Y Huang, C Eizaguirre, M Kalbe, ...
PLoS Genetics 11 (2), e1004966, 2015
Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load
PJ McLaren, C Coulonges, I Bartha, TL Lenz, AJ Deutsch, A Bashirova, ...
Proceedings of the National Academy of Sciences 112 (47), 14658-14663, 2015
Major histocompatibility complex polymorphism: dynamics and consequences of parasite‐mediated local adaptation in fishes
C Eizaguirre, TL Lenz
Journal of Fish Biology 77 (9), 2023-2047, 2010
Speciation accelerated and stabilized by pleiotropic major histocompatibility complex immunogenes
C Eizaguirre, TL Lenz, A Traulsen, M Milinski
Ecology Letters 12 (1), 5-12, 2009
Exploring local immunological adaptation of two stickleback ecotypes by experimental infection and transcriptome‐wide digital gene expression analysis
TL Lenz, C Eizaguirre, B Rotter, M Kalbe, M Milinski
Molecular Ecology 22 (3), 774-786, 2013
Genome‐wide patterns of standing genetic variation in a marine population of three‐spined sticklebacks
PGD Feulner, FJJ Chain, M Panchal, C Eizaguirre, M Kalbe, TL Lenz, ...
Molecular Ecology 22 (3), 635-649, 2013
Evolutionary divergence of HLA class I genotype impacts efficacy of cancer immunotherapy
D Chowell, C Krishna, F Pierini, V Makarov, NA Rizvi, F Kuo, LGT Morris, ...
Nature Medicine 25 (11), 1715-1720, 2019
Diverse MHC IIB allele repertoire increases parasite resistance and body condition in the Long-tailed giant rat (Leopoldamys sabanus)
TL Lenz, K Wells, M Pfeiffer, S Sommer
BMC Evolutionary Biology 9, 269, 2009
Divergent allele advantage at human MHC genes: signatures of past and ongoing selection
F Pierini, TL Lenz
Molecular Biology and Evolution 35 (9), 2145-2158, 2018
Computational prediction of MHC II‐antigen binding supports divergent allele advantage and explains trans‐species polymorphism
TL Lenz
Evolution 65 (8), 2380-2390, 2011
Advances in the evolutionary understanding of MHC polymorphism
J Radwan, W Babik, J Kaufman, TL Lenz, J Winternitz
Trends in Genetics 36 (4), 298-311, 2020
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