Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo S El Andaloussi, T Lehto, I Mäger, K Rosenthal-Aizman, II Oprea, ... Nucleic acids research 39 (9), 3972-3987, 2011 | 327 | 2011 |
Functional correction in mouse models of muscular dystrophy using exon-skipping tricyclo-DNA oligomers A Goyenvalle, G Griffith, A Babbs, SE Andaloussi, K Ezzat, A Avril, ... Nature medicine 21 (3), 270-275, 2015 | 302 | 2015 |
PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation K Ezzat, S El Andaloussi, EM Zaghloul, T Lehto, S Lindberg, PMD Moreno, ... Nucleic acids research 39 (12), 5284-5298, 2011 | 288 | 2011 |
Peptides for nucleic acid delivery T Lehto, K Ezzat, MJA Wood, SEL Andaloussi Advanced drug delivery reviews 106, 172-182, 2016 | 226 | 2016 |
The viral protein corona directs viral pathogenesis and amyloid aggregation K Ezzat, M Pernemalm, S Pålsson, TC Roberts, P Järver, A Dondalska, ... Nature communications 10 (1), 2331, 2019 | 185 | 2019 |
C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia Y Aoki, R Manzano, Y Lee, R Dafinca, M Aoki, AGL Douglas, MA Varela, ... Brain 140 (4), 887-897, 2017 | 174 | 2017 |
Scavenger receptor‐mediated uptake of cell‐penetrating peptide nanocomplexes with oligonucleotides K Ezzat, H Helmfors, O Tudoran, C Juks, S Lindberg, K Padari, ... The FASEB Journal 26 (3), 1172-1180, 2012 | 162 | 2012 |
Delivery of nucleic acids with a stearylated (RxR) 4 peptide using a non-covalent co-incubation strategy T Lehto, R Abes, N Oskolkov, J Suhorutšenko, DM Copolovici, I Mäger, ... Journal of Controlled Release 141 (1), 42-51, 2010 | 151 | 2010 |
A peptide-based vector for efficient gene transfer in vitro and in vivo T Lehto, OE Simonson, I Mäger, K Ezzat, H Sork, DM Copolovici, JR Viola, ... Molecular Therapy 19 (8), 1457-1467, 2011 | 138 | 2011 |
Self-assembly into nanoparticles is essential for receptor mediated uptake of therapeutic antisense oligonucleotides K Ezzat, Y Aoki, T Koo, G McClorey, L Benner, A Coenen-Stass, ... Nano letters 15 (7), 4364-4373, 2015 | 103 | 2015 |
PepFect14 peptide vector for efficient gene delivery in cell cultures KL Veiman, I Mäger, K Ezzat, H Margus, T Lehto, K Langel, K Kurrikoff, ... Molecular pharmaceutics 10 (1), 199-210, 2013 | 101 | 2013 |
High cerebrospinal amyloid-β 42 is associated with normal cognition in individuals with brain amyloidosis A Sturchio, AK Dwivedi, CB Young, T Malm, L Marsili, JS Sharma, ... EClinicalMedicine 38, 2021 | 87 | 2021 |
Solid formulation of cell-penetrating peptide nanocomplexes with siRNA and their stability in simulated gastric conditions K Ezzat, EM Zaghloul, SEL Andaloussi, T Lehto, R El-Sayed, T Magdy, ... Journal of controlled release 162 (1), 1-8, 2012 | 65 | 2012 |
A convergent uptake route for peptide-and polymer-based nucleotide delivery systems S Lindberg, J Regberg, J Eriksson, H Helmfors, A Muñoz-Alarcón, ... Journal of controlled release 206, 58-66, 2015 | 47 | 2015 |
Synthetic SiRNA delivery: progress and prospects TC Roberts, K Ezzat, S El Andaloussi, MS Weinberg SiRNA Delivery Methods: Methods and Protocols, 291-310, 2016 | 45 | 2016 |
Peptide-based matrices as drug delivery vehicles K Ezzat, SE Andaloussi, R Abdo, U Langel Current pharmaceutical design 16 (9), 1167-1178, 2010 | 44 | 2010 |
Soluble amyloid-β consumption in Alzheimer’s disease AJ Espay, A Sturchio, LS Schneider, K Ezzat Journal of Alzheimer's Disease 82 (4), 1403-1415, 2021 | 40 | 2021 |
Role of autophagy in cell-penetrating peptide transfection model M Dowaidar, M Gestin, CP Cerrato, MH Jafferali, H Margus, PA Kivistik, ... Scientific Reports 7 (1), 12635, 2017 | 32 | 2017 |
High soluble amyloid-β 42 predicts normal cognition in amyloid-positive individuals with Alzheimer’s disease-causing mutations A Sturchio, AK Dwivedi, T Malm, MJA Wood, R Cilia, JS Sharma, EJ Hill, ... Journal of Alzheimer's Disease 90 (1), 333-348, 2022 | 29 | 2022 |
Phenotype-agnostic molecular subtyping of neurodegenerative disorders: The Cincinnati Cohort Biomarker Program (CCBP) A Sturchio, L Marsili, JA Vizcarra, AK Dwivedi, MA Kauffman, AP Duker, ... Frontiers in Aging Neuroscience 12, 553635, 2020 | 27 | 2020 |