| Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance A Kallies, ED Hawkins, GT Belz, D Metcalf, M Hommel, LM Corcoran, ... Nature immunology 7 (5), 466-474, 2006 | 413 | 2006 |
| Inhibition of endosteal vascular niche remodeling rescues hematopoietic stem cell loss in AML D Duarte, ED Hawkins, O Akinduro, H Ang, K De Filippo, IY Kong, ... Cell stem cell 22 (1), 64-77. e6, 2018 | 301 | 2018 |
| Measuring lymphocyte proliferation, survival and differentiation using CFSE time-series data ED Hawkins, M Hommel, ML Turner, FL Battye, JF Markham, PD Hodgkin Nature protocols 2 (9), 2057-2067, 2007 | 296 | 2007 |
| MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis AL Samson, Y Zhang, ND Geoghegan, XJ Gavin, KA Davies, ... Nature communications 11 (1), 3151, 2020 | 247 | 2020 |
| Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease N Lalaoui, SE Boyden, H Oda, GM Wood, DL Stone, D Chau, L Liu, ... Nature 577 (7788), 103-108, 2020 | 247 | 2020 |
| Activation-induced B cell fates are selected by intracellular stochastic competition KR Duffy, CJ Wellard, JF Markham, JHS Zhou, R Holmberg, ED Hawkins, ... Science 335 (6066), 338, 2012 | 237 | 2012 |
| Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth JB Baell, DJ Leaver, SJ Hermans, GL Kelly, MS Brennan, NL Downer, ... Nature 560 (7717), 253-257, 2018 | 222 | 2018 |
| T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments ED Hawkins, D Duarte, O Akinduro, RA Khorshed, D Passaro, M Nowicka, ... Nature 538 (7626), 518-522, 2016 | 211 | 2016 |
| A model of immune regulation as a consequence of randomized lymphocyte division and death times ED Hawkins, ML Turner, MR Dowling, C Van Gend, PD Hodgkin Proceedings of the National Academy of Sciences 104 (12), 5032-5037, 2007 | 199 | 2007 |
| A single-cell pedigree analysis of alternative stochastic lymphocyte fates ED Hawkins, JF Markham, LP McGuinness, PD Hodgkin Proceedings of the National Academy of Sciences 106 (32), 13457-13462, 2009 | 168 | 2009 |
| Asymmetric cell division of T cells upon antigen presentation uses multiple conserved mechanisms J Oliaro, V Van Ham, F Sacirbegovic, A Pasam, Z Bomzon, K Pham, ... The Journal of Immunology 185 (1), 367-375, 2010 | 165 | 2010 |
| The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer SJ Vervoort, SA Welsh, JR Devlin, E Barbieri, DA Knight, S Offley, ... Cell 184 (12), 3143-3162. e32, 2021 | 134 | 2021 |
| Click chemistry enables preclinical evaluation of targeted epigenetic therapies DS Tyler, J Vappiani, T Cañeque, EYN Lam, A Ward, O Gilan, YC Chan, ... Science 356 (6345), 1397-1401, 2017 | 134 | 2017 |
| The interplay of leukemia cells and the bone marrow microenvironment D Duarte, ED Hawkins, C Lo Celso Blood, The Journal of the American Society of Hematology 131 (14), 1507-1511, 2018 | 118 | 2018 |
| Asymmetric segregation and self-renewal of hematopoietic stem and progenitor cells with endocytic Ap2a2 SB Ting, E Deneault, K Hope, S Cellot, J Chagraoui, N Mayotte, JF Dorn, ... Blood, The Journal of the American Society of Hematology 119 (11), 2510-2522, 2012 | 112 | 2012 |
| Proliferation dynamics of acute myeloid leukaemia and haematopoietic progenitors competing for bone marrow space O Akinduro, TS Weber, H Ang, MLR Haltalli, N Ruivo, D Duarte, ... Nature communications 9 (1), 1-12, 2018 | 92 | 2018 |
| Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway DS Simpson, J Pang, A Weir, IY Kong, M Fritsch, M Rashidi, JP Cooney, ... Immunity 55 (3), 423-441. e9, 2022 | 86 | 2022 |
| Loss of host type-I IFN signaling accelerates metastasis and impairs NK-cell antitumor function in multiple models of breast cancer J Rautela, N Baschuk, CY Slaney, KM Jayatilleke, K Xiao, BN Bidwell, ... Cancer immunology research 3 (11), 1207-1217, 2015 | 84 | 2015 |
| Excitatory pathways from the lateral habenula enable propofol-induced sedation C Gelegen, G Miracca, MZ Ran, EC Harding, Z Ye, X Yu, K Tossell, ... Current Biology 28 (4), 580-587. e5, 2018 | 83 | 2018 |
| Manipulation of B-cell responses with histone deacetylase inhibitors M Waibel, AJ Christiansen, ML Hibbs, J Shortt, SA Jones, I Simpson, ... Nature communications 6 (1), 6838, 2015 | 82 | 2015 |
Delfim Duartei3S / IPO-Porto / FMUPDirección de correo verificada de med.up.pt
