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Leonardo Pardo
Leonardo Pardo
Laboratorio de Medicina Computacional, Universidad Autonoma de Barcelona
Verified email at uab.es
Title
Cited by
Cited by
Year
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
A Manglik, AC Kruse, TS Kobilka, FS Thian, JM Mathiesen, RK Sunahara, ...
Nature 485 (7398), 321-326, 2012
15962012
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor
MP Bokoch, Y Zou, SGF Rasmussen, CW Liu, R Nygaard, ...
Nature 463 (7277), 108-112, 2010
5842010
A molecular dissection of the glycoprotein hormone receptors
G Vassart, L Pardo, S Costagliola
Trends in biochemical sciences 29 (3), 119-126, 2004
3932004
Glycoprotein hormone receptors: determinants in leucine‐rich repeats responsible for ligand specificity
G Smits, M Campillo, C Govaerts, V Janssens, C Richter, G Vassart, ...
The EMBO journal, 2003
2322003
Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors
X Viñals, E Moreno, L Lanfumey, A Cordomí, A Pastor, R de La Torre, ...
PLoS biology 13 (7), e1002194, 2015
2212015
Ligand‐regulated oligomerization of β2‐adrenoceptors in a model lipid bilayer
JJ Fung, X Deupi, L Pardo, XJ Yao, GA Velez‐Ruiz, BT DeVree, ...
The EMBO journal 28 (21), 3315-3328, 2009
2212009
Pharmacogenomic and structural analysis of constitutive G protein–coupled receptor activity
MJ Smit, HF Vischer, RA Bakker, A Jongejan, H Timmerman, L Pardo, ...
Annu. Rev. Pharmacol. Toxicol. 47 (1), 53-87, 2007
2182007
Serine and threonine residues bend α-helices in the χ1= g− conformation
JA Ballesteros, X Deupi, M Olivella, EEJ Haaksma, L Pardo
Biophysical journal 79 (5), 2754-2760, 2000
2072000
Serotonin 5-HT6 Receptor Antagonists for the Treatment of Cognitive Deficiency in Alzheimer’s Disease
B Benhamú, M Martín-Fontecha, H Vázquez-Villa, L Pardo, ...
Journal of medicinal chemistry 57 (17), 7160-7181, 2014
1682014
The TXP motif in the second transmembrane helix of CCR5: a structural determinant of chemokine-induced activation
C Govaerts, C Blanpain, X Deupi, S Ballet, JA Ballesteros, SJ Wodak, ...
Journal of Biological Chemistry 276 (16), 13217-13225, 2001
1682001
Membrane protein simulations using AMBER force field and Berger lipid parameters
A Cordomi, G Caltabiano, L Pardo
Journal of chemical theory and computation 8 (3), 948-958, 2012
1672012
Synthesis and pharmacophore modeling of naphthoquinone derivatives with cytotoxic activity in human promyelocytic leukemia HL-60 cell line
E Pérez-Sacau, RG Díaz-Peñate, A Estévez-Braun, AG Ravelo, ...
Journal of medicinal chemistry 50 (4), 696-706, 2007
1622007
The role of internal water molecules in the structure and function of the rhodopsin family of G protein‐coupled receptors
L Pardo, X Deupi, N Dölker, ML López‐Rodríguez, M Campillo
ChemBioChem 8 (1), 19-24, 2007
1462007
An activation switch in the rhodopsin family of G protein-coupled receptors: the thyrotropin receptor
E Urizar, S Claeysen, X Deupí, C Govaerts, S Costagliola, G Vassart, ...
Journal of Biological Chemistry 280 (17), 17135-17141, 2005
1372005
Interactions between intracellular domains as key determinants of the quaternary structure and function of receptor heteromers
G Navarro, S Ferré, A Cordomi, E Moreno, J Mallol, V Casadó, A Cortés, ...
Journal of Biological Chemistry 285 (35), 27346-27359, 2010
1332010
Quaternary structure of a G-protein-coupled receptor heterotetramer in complex with Gi and Gs
G Navarro, A Cordomí, M Zelman-Femiak, M Brugarolas, E Moreno, ...
BMC biology 14, 1-12, 2016
1292016
A conserved Asn in transmembrane helix 7 is an on/off switch in the activation of the thyrotropin receptor
C Govaerts, A Lefort, S Costagliola, SJ Wodak, JA Ballesteros, ...
Journal of Biological Chemistry 276 (25), 22991-22999, 2001
1272001
On the use of the transmembrane domain of bacteriorhodopsin as a template for modeling the three-dimensional structure of guanine nucleotide-binding regulatory protein-coupled …
L Pardo, JA Ballesteros, R Osman, H Weinstein
Proceedings of the National Academy of Sciences 89 (9), 4009-4012, 1992
1271992
A Three-Dimensional Pharmacophore Model for 5-Hydroxytryptamine6 (5-HT6) Receptor Antagonists
ML López-Rodríguez, B Benhamú, T De La Fuente, A Sanz, L Pardo, ...
Journal of medicinal chemistry 48 (13), 4216-4219, 2005
1242005
Activation of CCR5 by chemokines involves an aromatic cluster between transmembrane helices 2 and 3
C Govaerts, A Bondue, JY Springael, M Olivella, X Deupi, E Le Poul, ...
Journal of Biological Chemistry 278 (3), 1892-1903, 2003
1182003
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