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Jimmy DaSilva
Jimmy DaSilva
Verified email at merck.com
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Cited by
Cited by
Year
Adsorbent screening for metal impurity removal in pharmaceutical process research
CJ Welch, J Albaneze-Walker, WR Leonard, M Biba, J DaSilva, ...
Organic process research & development 9 (2), 198-205, 2005
2662005
Preparative chiral SFC as a green technology for rapid access to enantiopurity in pharmaceutical process research
RE Majors
Advanstar Communications 131, 2005
1042005
Chaotropic effects in sub/supercritical fluid chromatography via ammonium hydroxide in water-rich modifiers: enabling separation of peptides and highly polar pharmaceuticals at …
J Liu, AA Makarov, R Bennett, IA Haidar Ahmad, J DaSilva, M Reibarkh, ...
Analytical chemistry 91 (21), 13907-13915, 2019
602019
Green chemistry articles of interest to the pharmaceutical industry
I Andrews, J Cui, J DaSilva, L Dudin, P Dunn, J Hayler, B Hinkley, ...
Organic process research & development 13 (3), 397-408, 2009
542009
Evaluation of non-conventional polar modifiers on immobilized chiral stationary phases for improved resolution of enantiomers by supercritical fluid chromatography
JO DaSilva, B Coes, L Frey, I Mergelsberg, R McClain, L Nogle, CJ Welch
Journal of Chromatography A 1328, 98-103, 2014
392014
A rapid catalytic asymmetric synthesis of 1, 3, 4-trisubstituted pyrrolidines
KM Belyk, CD Beguin, M Palucki, N Grinberg, J DaSilva, D Askin, ...
Tetrahedron letters 45 (16), 3265-3268, 2004
342004
Generic enhanced sub/supercritical fluid chromatography: blueprint for highly productive and sustainable separation of primary hindered amines
JO DaSilva, D Lehnherr, J Liu, R Bennett, IA Haidar Ahmad, M Hicks, ...
ACS sustainable chemistry & engineering 8 (15), 6011-6021, 2020
302020
Enantioselective UHPLC Screening Combined with In Silico Modeling for Streamlined Development of Ultrafast Enantiopurity Assays
GL Losacco, H Wang, IA Haidar Ahmad, J DaSilva, AA Makarov, ...
Analytical Chemistry 94 (3), 1804-1812, 2021
292021
Expanding the range of sub/supercritical fluid chromatography: advantageous use of methanesulfonic acid in water-rich modifiers for peptide analysis
GL Losacco, JO DaSilva, J Liu, EL Regalado, JL Veuthey, D Guillarme
Journal of Chromatography A 1642, 462048, 2021
282021
Mapping the separation landscape of pharmaceuticals: rapid and efficient scale-up of preparative purifications enabled by computer-assisted chromatographic method development
R Bennett, IA Haidar Ahmad, J DaSilva, M Figus, K Hullen, FR Tsay, ...
Organic Process Research & Development 23 (12), 2678-2684, 2019
192019
Impurity isolation in support of pharmaceutical process research
M Biba, CJ Welch, JO Da Silva, DJ Mathre
Am. Pharm. Rev 8, 68-72, 2005
182005
Interlaboratory study of a Supercritical Fluid Chromatography method for the determination of pharmaceutical impurities: evaluation of multi-systems reproducibility
A Dispas, A Clarke, A Grand-Guillaume Perrenoud, LG Losacco, ...
Journal of Pharmaceutical and Biomedical Analysis, 114206, 2021
162021
Doing more with less: Evaluation of the use of high linear velocities in preparative supercritical fluid chromatography
JO DaSilva, R Bennett, BF Mann
Journal of Chromatography A 1595, 199-206, 2019
142019
Dual‐gradient unified chromatography: a new paradigm for versatility in simultaneous multicomponent analysis
GL Losacco, R Bennett, IAH Ahmad, RC Barrientos, JO DaSilva, Y Dong, ...
Angewandte Chemie International Edition 61 (45), e202208854, 2022
102022
Automated ion exchange chromatography screening combined with in silico multifactorial simulation for efficient method development and purification of biopharmaceutical targets
GL Losacco, MB Hicks, JO DaSilva, H Wang, M Potapenko, FR Tsay, ...
Analytical and Bioanalytical Chemistry 414 (12), 3581-3591, 2022
102022
Green chemistry articles of interest to the pharmaceutical industry
S Challenger, L Dudin, J DaSilva, P Dunn, T Govaerts, J Hayler, B Hinkley, ...
Organic Process Research & Development 12 (5), 807-816, 2008
102008
syn-2, 3-Disubstituted-2, 3-dihydro-1, 4-benzoxathiin rings: preparation from quinone ketals and 2-mercaptoethanols
PG Dormer, AM Kassim, JL Leazer Jr, F Lang, F Xu, KA Savary, ...
Tetrahedron letters 45 (28), 5429-5432, 2004
102004
Parallel chiral sub/supercritical fluid chromatography screening as a framework for accelerated purification of pharmaceutical targets
GL Losacco, JO DaSilva, IAH Ahmad, I Mangion, TA Berger, EL Regalado
Journal of Chromatography A 1674, 463094, 2022
92022
A Novel Crystallization-Induced Diastereomeric Transformation Based on a Reversible Carbon− Sulfur Bond Formation. Application to the Synthesis of a γ-Secretase Inhibitor
AJ Davies, JP Scott, BC Bishop, KMJ Brands, SE Brewer, JO DaSilva, ...
The Journal of Organic Chemistry 72 (13), 4864-4871, 2007
92007
Preparation and evaluation of novel stationary phases for improved chromatographic purification of pneumocandin B0
CJ Welch, JO DaSilva, J Nti-Gyabaah, F Antia, K Goklen, R Boyd
Journal of Chromatography A 1101 (1-2), 204-213, 2006
92006
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