Adsorbent screening for metal impurity removal in pharmaceutical process research CJ Welch, J Albaneze-Walker, WR Leonard, M Biba, J DaSilva, ... Organic process research & development 9 (2), 198-205, 2005 | 266 | 2005 |
Preparative chiral SFC as a green technology for rapid access to enantiopurity in pharmaceutical process research RE Majors Advanstar Communications 131, 2005 | 104 | 2005 |
Chaotropic effects in sub/supercritical fluid chromatography via ammonium hydroxide in water-rich modifiers: enabling separation of peptides and highly polar pharmaceuticals at … J Liu, AA Makarov, R Bennett, IA Haidar Ahmad, J DaSilva, M Reibarkh, ... Analytical chemistry 91 (21), 13907-13915, 2019 | 60 | 2019 |
Green chemistry articles of interest to the pharmaceutical industry I Andrews, J Cui, J DaSilva, L Dudin, P Dunn, J Hayler, B Hinkley, ... Organic process research & development 13 (3), 397-408, 2009 | 54 | 2009 |
Evaluation of non-conventional polar modifiers on immobilized chiral stationary phases for improved resolution of enantiomers by supercritical fluid chromatography JO DaSilva, B Coes, L Frey, I Mergelsberg, R McClain, L Nogle, CJ Welch Journal of Chromatography A 1328, 98-103, 2014 | 39 | 2014 |
A rapid catalytic asymmetric synthesis of 1, 3, 4-trisubstituted pyrrolidines KM Belyk, CD Beguin, M Palucki, N Grinberg, J DaSilva, D Askin, ... Tetrahedron letters 45 (16), 3265-3268, 2004 | 34 | 2004 |
Generic enhanced sub/supercritical fluid chromatography: blueprint for highly productive and sustainable separation of primary hindered amines JO DaSilva, D Lehnherr, J Liu, R Bennett, IA Haidar Ahmad, M Hicks, ... ACS sustainable chemistry & engineering 8 (15), 6011-6021, 2020 | 30 | 2020 |
Enantioselective UHPLC Screening Combined with In Silico Modeling for Streamlined Development of Ultrafast Enantiopurity Assays GL Losacco, H Wang, IA Haidar Ahmad, J DaSilva, AA Makarov, ... Analytical Chemistry 94 (3), 1804-1812, 2021 | 29 | 2021 |
Expanding the range of sub/supercritical fluid chromatography: advantageous use of methanesulfonic acid in water-rich modifiers for peptide analysis GL Losacco, JO DaSilva, J Liu, EL Regalado, JL Veuthey, D Guillarme Journal of Chromatography A 1642, 462048, 2021 | 28 | 2021 |
Mapping the separation landscape of pharmaceuticals: rapid and efficient scale-up of preparative purifications enabled by computer-assisted chromatographic method development R Bennett, IA Haidar Ahmad, J DaSilva, M Figus, K Hullen, FR Tsay, ... Organic Process Research & Development 23 (12), 2678-2684, 2019 | 19 | 2019 |
Impurity isolation in support of pharmaceutical process research M Biba, CJ Welch, JO Da Silva, DJ Mathre Am. Pharm. Rev 8, 68-72, 2005 | 18 | 2005 |
Interlaboratory study of a Supercritical Fluid Chromatography method for the determination of pharmaceutical impurities: evaluation of multi-systems reproducibility A Dispas, A Clarke, A Grand-Guillaume Perrenoud, LG Losacco, ... Journal of Pharmaceutical and Biomedical Analysis, 114206, 2021 | 16 | 2021 |
Doing more with less: Evaluation of the use of high linear velocities in preparative supercritical fluid chromatography JO DaSilva, R Bennett, BF Mann Journal of Chromatography A 1595, 199-206, 2019 | 14 | 2019 |
Dual‐gradient unified chromatography: a new paradigm for versatility in simultaneous multicomponent analysis GL Losacco, R Bennett, IAH Ahmad, RC Barrientos, JO DaSilva, Y Dong, ... Angewandte Chemie International Edition 61 (45), e202208854, 2022 | 10 | 2022 |
Automated ion exchange chromatography screening combined with in silico multifactorial simulation for efficient method development and purification of biopharmaceutical targets GL Losacco, MB Hicks, JO DaSilva, H Wang, M Potapenko, FR Tsay, ... Analytical and Bioanalytical Chemistry 414 (12), 3581-3591, 2022 | 10 | 2022 |
Green chemistry articles of interest to the pharmaceutical industry S Challenger, L Dudin, J DaSilva, P Dunn, T Govaerts, J Hayler, B Hinkley, ... Organic Process Research & Development 12 (5), 807-816, 2008 | 10 | 2008 |
syn-2, 3-Disubstituted-2, 3-dihydro-1, 4-benzoxathiin rings: preparation from quinone ketals and 2-mercaptoethanols PG Dormer, AM Kassim, JL Leazer Jr, F Lang, F Xu, KA Savary, ... Tetrahedron letters 45 (28), 5429-5432, 2004 | 10 | 2004 |
Parallel chiral sub/supercritical fluid chromatography screening as a framework for accelerated purification of pharmaceutical targets GL Losacco, JO DaSilva, IAH Ahmad, I Mangion, TA Berger, EL Regalado Journal of Chromatography A 1674, 463094, 2022 | 9 | 2022 |
A Novel Crystallization-Induced Diastereomeric Transformation Based on a Reversible Carbon− Sulfur Bond Formation. Application to the Synthesis of a γ-Secretase Inhibitor AJ Davies, JP Scott, BC Bishop, KMJ Brands, SE Brewer, JO DaSilva, ... The Journal of Organic Chemistry 72 (13), 4864-4871, 2007 | 9 | 2007 |
Preparation and evaluation of novel stationary phases for improved chromatographic purification of pneumocandin B0 CJ Welch, JO DaSilva, J Nti-Gyabaah, F Antia, K Goklen, R Boyd Journal of Chromatography A 1101 (1-2), 204-213, 2006 | 9 | 2006 |