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Alexander Schepsky
Alexander Schepsky
Project leader, University of Iceland
Verified email at hi.is
Title
Cited by
Cited by
Year
Novel MITF targets identified using a two‐step DNA microarray strategy
KS Hoek, NC Schlegel, OM Eichhoff, DS Widmer, C Praetorius, ...
Pigment cell & melanoma research 21 (6), 665-676, 2008
3182008
The microphthalmia-associated transcription factor Mitf interacts with β-catenin to determine target gene expression
A Schepsky, K Bruser, GJ Gunnarsson, J Goodall, JH Hallsson, ...
Molecular and cellular biology 26 (23), 8914-8927, 2006
2002006
Restricted leucine zipper dimerization and specificity of DNA recognition of the melanocyte master regulator MITF
V Pogenberg, MH Ögmundsdóttir, K Bergsteinsdóttir, A Schepsky, ...
Genes & development 26 (23), 2647-2658, 2012
1622012
MITF mutations associated with pigment deficiency syndromes and melanoma have different effects on protein function
C Grill, K Bergsteinsdóttir, MH Ögmundsdóttir, V Pogenberg, A Schepsky, ...
Human Molecular Genetics 22 (21), 4357-4367, 2013
762013
The role of MITF phosphorylation sites during coat color and eye development in mice analyzed by bacterial artificial chromosome transgene rescue
GL Bauer, C Praetorius, K Bergsteinsdóttir, JH Hallsson, BK Gísladóttir, ...
Genetics 183 (2), 581-594, 2009
702009
C-KIT signaling depends on microphthalmia-associated transcription factor for effects on cell proliferation
B Phung, J Sun, A Schepsky, E Steingrimsson, L Rönnstrand
PloS one 6 (8), e24064, 2011
672011
Evolutionary sequence comparison of the Mitf gene reveals novel conserved domains
JH Hallsson, BS Haflidadóttir, A Schepsky, H Arnheiter, E Steingrímsson
Pigment cell research 20 (3), 185-200, 2007
522007
Tuning transcription factor availability through acetylation-mediated genomic redistribution
P Louphrasitthiphol, R Siddaway, A Loffreda, V Pogenberg, ...
Molecular cell 79 (3), 472-487. e10, 2020
482020
ECM1 secreted by HER2-overexpressing breast cancer cells promotes formation of a vascular niche accelerating cancer cell migration and invasion
SS Steinhaeuser, E Morera, Z Budkova, A Schepsky, Q Wang, O Rolfsson, ...
Laboratory Investigation 100 (7), 928-944, 2020
422020
Aminopeptidase expression in multiple myeloma associates with disease progression and sensitivity to melflufen
JJ Miettinen, R Kumari, GA Traustadottir, ME Huppunen, P Sergeev, ...
Cancers 13 (7), 1527, 2021
382021
Subcellular localization and stability of MITF are modulated by the bHLH‐Zip domain
V Fock, SR Gudmundsson, HO Gunnlaugsson, JA Stefansson, V Ionasz, ...
Pigment cell & melanoma research 32 (1), 41-54, 2019
312019
Melflufen, a peptide‐conjugated alkylator, is an efficient anti‐neo‐plastic drug in breast cancer cell lines
A Schepsky, GA Traustadottir, JP Joelsson, S Ingthorsson, J Kricker, ...
Cancer Medicine 9 (18), 6726-6738, 2020
112020
Acetylation reprograms MITF target selectivity and residence time
P Louphrasitthiphol, A Loffreda, V Pogenberg, S Picaud, A Schepsky, ...
Nature Communications 14 (1), 6051, 2023
32023
Elucidation of c-KIT-dependent signaling to MITF
B Phung, J Sun, A Schepsky, E Steingrimsson, L Rönnstrand
Cancer Research 72 (8_Supplement), 3093-3093, 2012
32012
Melflufen, a peptide-conjugated alkylator, shows efficacy in breast cancer cell lines
A Schepsky, GA Traustadottir, JP Joelsson, S Ingthorsson, J Kricker, ...
Cancer Research 80 (16_Supplement), 5205-5205, 2020
2020
Dimerization and DNA binding specificities unravelled by the structure of MITF
V Pogenberg, MH Ogmundsdottir, K Bergsteinsdottir, M Milewski, ...
Cancer Research 72 (8_Supplement), 2221-2221, 2012
2012
The role of Interferon Regulatory Factor 4 IRF4 in pigmentation
C Grill, C Praetorius, A Schepsky, E Steingrimsson
PIGMENT CELL & MELANOMA RESEARCH 24 (4), 809-809, 2011
2011
The particular mechanisms of DNA recognition and dimerization of MITF
V Pogenberg, M Milewski, V Deineko, A Schepsky, E Steingrimsson, ...
Acta Crystallographica Section A 67, C687-C687, 2011
2011
The Mitf structure unravels DNA binding and dimerization specificities
V Pogenberg, MH Ogmundsdottir, K Bergsteinsdottir, M Milewski, ...
PIGMENT CELL & MELANOMA RESEARCH 24 (4), 799-799, 2011
2011
C-Kit and Mitf signaling: Novel involvement of the PI3K/Akt and p38 pathways
B Phung, A Schepsky, E Steingrimsson, L Rönnstrand
Cancer Research 70 (8_Supplement), 3953-3953, 2010
2010
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Articles 1–20