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Gilberto Valdes
Gilberto Valdes
Investigator, GSK
Verified email at gsk.com
Title
Cited by
Cited by
Year
Direct generation of protein conformational ensembles via machine learning
G Janson, G Valdes-Garcia, L Heo, M Feig
Nature Communications 14 (1), 774, 2023
552023
Combinatorial Multicomponent Access to Natural‐Products‐Inspired Peptidomimetics: Discovery of Selective Inhibitors of Microbial Metallo‐aminopeptidases
Y Méndez, K Pérez‐Labrada, J González‐Bacerio, G Valdés, ...
ChemMedChem 9 (10), 2351-2359, 2014
292014
Inhibition of light chain 6aJL2-R24G amyloid fiber formation associated with light chain amyloidosis
AE Pelaez-Aguilar, L Rivillas-Acevedo, L French-Pacheco, ...
Biochemistry 54 (32), 4978-4986, 2015
212015
Effect of divalent cations on the porcine kidney cortex membrane-bound form of dipeptidyl peptidase IV
I Pascual, H Gómez, T Pons, M Chappé, MA Vargas, G Valdés, A Lopéz, ...
The International Journal of Biochemistry & Cell Biology 43 (3), 363-371, 2011
212011
The Hcp-like protein HilE inhibits homodimerization and DNA binding of the virulence-associated transcriptional regulator HilD in Salmonella
CC Paredes-Amaya, G Valdés-García, VR Juárez-González, ...
Journal of Biological Chemistry 293 (17), 6578-6592, 2018
192018
Modeling concentration-dependent phase separation processes involving peptides and RNA via residue-based coarse-graining
G Valdes-Garcia, L Heo, LJ Lapidus, M Feig
Journal of Chemical Theory and Computation 19 (2), 669-678, 2023
162023
Convergent mechanisms favor fast amyloid formation in two lambda 6a Ig light chain mutants
G Valdés‐García, C Millan-Pacheco, N Pastor
Biopolymers 107 (8), e23027, 2017
122017
Site-Specific Interactions with Copper Promote Amyloid Fibril Formation for λ6aJL2-R24G
AE Pelaez-Aguilar, G Valdés-García, L French-Pacheco, N Pastor, ...
ACS omega 5 (13), 7085-7095, 2020
102020
Localized conformational changes trigger the pH-induced fibrillogenesis of an amyloidogenic λ light chain protein
I Velázquez-López, G Valdés-García, SR Romero, RM Martínez, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1862 (7), 1656-1666, 2018
102018
A family 13 thioesterase isolated from an activated sludge metagenome: I nsights into aromatic compounds metabolism
A Sánchez‐Reyez, RA Batista‐García, G Valdés‐García, E Ortiz, ...
Proteins: Structure, Function, and Bioinformatics 85 (7), 1222-1237, 2017
92017
Different dynamics in 6aJL2 proteins associated with AL amyloidosis, a conformational disease
R Maya-Martinez, L French-Pacheco, G Valdés-García, N Pastor, ...
International Journal of Molecular Sciences 20 (17), 4078, 2019
72019
Identification of a novel carbohydrate esterase from Bjerkandera adusta: Structural and function predictions through bioinformatics analysis and molecular modeling
LI Cuervo‐Soto, G Valdés‐García, R Batista‐García, ...
Proteins: Structure, Function, and Bioinformatics 83 (3), 533-546, 2015
72015
Unfolding and aggregation pathways of variable domains from immunoglobulin light chains
Y Meunier-Carmenate, G Valdés-García, R Maya-Martinez, ...
Biochemistry 62 (5), 1000-1011, 2023
42023
The effect of polymer length in liquid-liquid phase separation
G Valdes-Garcia, K Gamage, C Smith, K Martirosova, M Feig, LJ Lapidus
Cell Reports Physical Science 4 (5), 2023
22023
The Effect of Polymer Length in Phase Separation
K Gamage, G Valdes-Garcia, C Smith, K Martirosova, M Feig, L Lapidus
APS March Meeting Abstracts 2023, Q25. 002, 2023
2023
The Effect of Polymer Length in Phase Separation
G Valdes-Garcia, K Gamage, C Smith, K Martirosova, M Feig, LJ Lapidus
bioRxiv, 2022.11. 21.517354, 2022
2022
Characterizing Transient Protein–Protein Interactions by Trp-Cys Quenching and Computer Simulations
L Heo, K Gamage, G Valdes-Garcia, LJ Lapidus, M Feig
The journal of physical chemistry letters 13 (43), 10175-10182, 2022
2022
EGCG Inhibits Fibrillation of Light Chain 6aJL2-R24G, Associated with Light Chain Amyloidosis
AE Peláez-Aguilar, LAR Acevedo, LF Pacheco, GV García, RM Martínez, ...
Biophysical Journal 114 (3), 579a-580a, 2018
2018
Localized conformational changes trigger the pH-induced fibrillogenesis of an amyloidogenic λ light chain protein.
IV López, G Valdés-García, SR Romero, R Maya, AI Martínez, M Costas, ...
2018
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