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Harel Weinstein
Harel Weinstein
Professor of Professor of Physiology and Biophysics, Weill Cornell Medicine, Cornell U.
Verified email at med.cornell.edu - Homepage
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Cited by
Year
[19] Integrated methods for the construction of three-dimensional models and computational probing of structure-function relations in G protein-coupled receptors
JA Ballesteros, H Weinstein
Methods in neurosciences 25, 366-428, 1995
31671995
Functional selectivity and classical concepts of quantitative pharmacology
JD Urban, WP Clarke, M Von Zastrow, DE Nichols, B Kobilka, H Weinstein, ...
Journal of Pharmacology and Experimental Therapeutics 320 (1), 1-13, 2007
13152007
Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac
M Max, YG Shanker, L Huang, M Rong, Z Liu, F Campagne, H Weinstein, ...
Nature genetics 28 (1), 58-63, 2001
6852001
Molecular mechanisms of ligand interaction with the gonadotropin-releasing hormone receptor
SC Sealfon, H Weinstein, RP Millar
Endocrine reviews 18 (2), 180-205, 1997
6041997
Agonists induce conformational changes in transmembrane domains III and VI of the β2 adrenoceptor
U Gether, S Lin, P Ghanouni, JA Ballesteros, H Weinstein, BK Kobilka
The EMBO journal, 1997
5051997
The mechanism of a neurotransmitter: sodium symporter—inward release of Na+ and substrate is triggered by substrate in a second binding site
L Shi, M Quick, Y Zhao, H Weinstein, JA Javitch
Molecular cell 30 (6), 667-677, 2008
4282008
The binding sites for cocaine and dopamine in the dopamine transporter overlap
T Beuming, J Kniazeff, ML Bergmann, L Shi, L Gracia, K Raniszewska, ...
Nature neuroscience 11 (7), 780-789, 2008
4132008
Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation
Y Han, IS Moreira, E Urizar, H Weinstein, JA Javitch
Nature chemical biology 5 (9), 688-695, 2009
4002009
Structural instability of a constitutively active G protein-coupled receptor: agonist-independent activation due to conformational flexibility
U Gether, R Seifert, JA Ballesteros, E Sanders-Bush, H Weinstein, ...
Journal of Biological Chemistry 272 (5), 2587-2590, 1997
3531997
Hinges, swivels and switches: the role of prolines in signalling via transmembrane α-helices
MSP Sansom, H Weinstein
Trends in pharmacological sciences 21 (11), 445-451, 2000
3512000
Functional microdomains in G-protein-coupled receptors: the conserved arginine-cage motif in the gonadotropin-releasing hormone receptor
J Ballesteros, S Kitanovic, F Guarnieri, P Davies, BJ Fromme, K Konvicka, ...
Journal of Biological Chemistry 273 (17), 10445-10453, 1998
3301998
A reciprocal mutation supports helix 2 and helix 7 proximity in the gonadotropin-releasing hormone receptor.
W Zhou, C Flanagan, JA Ballesteros, K Konvicka, JS Davidson, ...
Molecular pharmacology 45 (2), 165-170, 1994
3251994
A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and …
T Beuming, L Shi, JA Javitch, H Weinstein
Molecular pharmacology 70 (5), 1630-1642, 2006
3242006
Single-molecule analysis of ligand efficacy in β2AR–G-protein activation
GG Gregorio, M Masureel, D Hilger, DS Terry, M Juette, H Zhao, Z Zhou, ...
Nature 547 (7661), 68-73, 2017
3202017
Crosstalk in G protein-coupled receptors: changes at the transmembrane homodimer interface determine activation
W Guo, L Shi, M Filizola, H Weinstein, JA Javitch
Proceedings of the National Academy of Sciences 102 (48), 17495-17500, 2005
3192005
A detailed interpretation of OH radical footprints in a TBP-DNA complex reveals the role of dynamics in the mechanism of sequence-specific binding
N Pastor, H Weinstein, E Jamison, M Brenowitz
Journal of molecular biology 304 (1), 55-68, 2000
3122000
Single-molecule dynamics of gating in a neurotransmitter transporter homologue
Y Zhao, D Terry, L Shi, H Weinstein, SC Blanchard, JA Javitch
Nature 465 (7295), 188-193, 2010
2802010
Related Contribution of Specific Helix 2 and 7 Residues to Conformational Activation of the Serotonin 5-HT2A Receptor (∗)
SC Sealfon, L Chi, BJ Ebersole, V Rodic, D Zhang, JA Ballesteros, ...
Journal of Biological Chemistry 270 (28), 16683-16688, 1995
2591995
Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue
Y Zhao, DS Terry, L Shi, M Quick, H Weinstein, SC Blanchard, JA Javitch
Nature 474 (7349), 109-113, 2011
2562011
PDZBase: a protein–protein interaction database for PDZ-domains
T Beuming, L Skrabanek, MY Niv, P Mukherjee, H Weinstein
Bioinformatics 21 (6), 827-828, 2005
2482005
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Articles 1–20