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Kazunari Nohara
Kazunari Nohara
Columbia University Irving Medical Center
Dirección de correo verificada de cumc.columbia.edu
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The small molecule nobiletin targets the molecular oscillator to enhance circadian rhythms and protect against metabolic syndrome
B He, K Nohara, N Park, YS Park, B Guillory, Z Zhao, JM Garcia, N Koike, ...
Cell metabolism 23 (4), 610-621, 2016
4372016
Nobiletin fortifies mitochondrial respiration in skeletal muscle to promote healthy aging against metabolic challenge
K Nohara, V Mallampalli, T Nemkov, M Wirianto, J Yang, Y Ye, Y Sun, ...
Nature communications 10 (1), 3923, 2019
1452019
Early-life exposure to testosterone programs the hypothalamic melanocortin system
K Nohara, Y Zhang, RS Waraich, A Laque, JP Tiano, J Tong, H Münzberg, ...
Endocrinology 152 (4), 1661-1669, 2011
1452011
Transmissible microbial and metabolomic remodeling by soluble dietary fiber improves metabolic homeostasis
B He, K Nohara, NJ Ajami, RD Michalek, X Tian, M Wong, ...
Scientific reports 5 (1), 10604, 2015
872015
Developmental androgen excess programs sympathetic tone and adipose tissue dysfunction and predisposes to a cardiometabolic syndrome in female mice
K Nohara, RS Waraich, S Liu, M Ferron, A Waget, MS Meyers, G Karsenty, ...
American Journal of Physiology-Endocrinology and Metabolism 304 (12), E1321 …, 2013
842013
Period2 3′-UTR and microRNA-24 regulate circadian rhythms by repressing PERIOD2 protein accumulation
SH Yoo, S Kojima, K Shimomura, N Koike, ED Buhr, T Furukawa, CH Ko, ...
Proceedings of the National Academy of Sciences 114 (42), E8855-E8864, 2017
812017
Central mechanisms of adiposity in adult female mice with androgen excess
K Nohara, A Laque, C Allard, H Münzberg, F Mauvais‐Jarvis
Obesity 22 (6), 1477-1484, 2014
712014
Myricetin improves endurance capacity and mitochondrial density by activating SIRT1 and PGC-1α
HY Jung, D Lee, HG Ryu, BH Choi, Y Go, N Lee, D Lee, HG Son, J Jeon, ...
Scientific reports 7 (1), 6237, 2017
592017
Ammonia-lowering activities and carbamoyl phosphate synthetase 1 (Cps1) induction mechanism of a natural flavonoid
K Nohara, Y Shin, N Park, K Jeong, B He, N Koike, SH Yoo, Z Chen
Nutrition & metabolism 12, 1-12, 2015
442015
Coordinate regulation of cholesterol and bile acid metabolism by the clock modifier nobiletin in metabolically challenged old mice
K Nohara, T Nemkov, A D’Alessandro, SH Yoo, Z Chen
International journal of molecular sciences 20 (17), 4281, 2019
432019
Manipulating the circadian and sleep cycles to protect against metabolic disease
K Nohara, SH Yoo, Z Chen
Frontiers in endocrinology 6, 35, 2015
432015
Dual attenuation of proteasomal and autophagic BMAL1 degradation in ClockΔ19/+ mice contributes to improved glucose homeostasis
K Jeong, B He, K Nohara, N Park, Y Shin, S Kim, K Shimomura, N Koike, ...
Scientific reports 5 (1), 12801, 2015
402015
T-2 toxin initially activates caspase-2 and induces apoptosis in U937 cells
P Huang, K Akagawa, Y Yokoyama, K Nohara, K Kano, K Morimoto
Toxicology letters 170 (1), 1-10, 2007
402007
Effects of the clock modulator nobiletin on circadian rhythms and pathophysiology in female mice of an Alzheimer’s disease model
E Kim, K Nohara, M Wirianto, G Escobedo Jr, JY Lim, R Morales, SH Yoo, ...
Biomolecules 11 (7), 1004, 2021
322021
Developmental androgen excess disrupts reproduction and energy homeostasis in adult male mice
K Nohara, S Liu, MS Meyers, A Waget, M Ferron, G Karsenty, R Burcelin, ...
J Endocrinol 219 (3), 259-268, 2013
312013
The clock modulator Nobiletin mitigates astrogliosis‐associated neuroinflammation and disease hallmarks in an Alzheimer’s disease model
M Wirianto, CY Wang, E Kim, N Koike, R Gomez‐Gutierrez, K Nohara, ...
The FASEB Journal 36 (3), 2022
262022
The important role of caspase-10 in sodium butyrate-induced apoptosis
K Nohara, Y Yokoyama, K Kano
Kobe J Med Sci 53 (5), 265-73, 2007
252007
Cardiolipin synthesis in skeletal muscle is rhythmic and modifiable by age and diet
K Nohara, E Kim, M Wirianto, E Mileykovskaya, W Dowhan, Z Chen, ...
Oxidative medicine and cellular longevity 2020, 2020
192020
Generation of reactive oxygen species is an early event in dolichyl phosphate‐induced apoptosis
Y Yokoyama, K Nohara, T Okubo, I Kano, K Akagawa, K Kano
Journal of cellular biochemistry 100 (2), 349-361, 2007
102007
The polymethoxyflavone sudachitin modulates the circadian clock and improves liver physiology
K Mawatari, N Koike, K Nohara, M Wirianto, T Uebanso, T Shimohata, ...
Molecular Nutrition & Food Research 67 (9), 2200270, 2023
72023
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