Luca Pinello

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Guo-Cheng YuanProfessor of Computational Biology, Icahn School of Medicine at Mount SinaiDirección de correo verificada de mssm.edu
Kendell ClementAssistant Professor, University of UtahDirección de correo verificada de utah.edu
Jonathan Y. HsuGraduate StudentDirección de correo verificada de mit.edu
Mitchel ColeMD/PhD Student, UCSFDirección de correo verificada de ucsf.edu
Martin J. AryeeAssociate Professor, Dept of Data Science, Dana Farber Cancer Institute & Dept of Pathology, HarvardDirección de correo verificada de ds.dfci.harvard.edu
Huidong ChenValo HealthDirección de correo verificada de valohealth.com
Sara P. GarciaMolecular Pathology Unit, Massachusetts General HospitalDirección de correo verificada de mgh.harvard.edu
Falak SherAssistant Professor, Columbia University New YorkDirección de correo verificada de cumc.columbia.edu
Shengdar Q. TsaiAssociate Member, St. Jude Children's Research HospitalDirección de correo verificada de stjude.org
Elenoe SmithPostdoctoral Fellow, Boston Children's HospitalDirección de correo verificada de bloodgroup.tch.harvard.edu
Partha Pratim DasPrincipal Investigator/ Lab head, BDI Monash UniversityDirección de correo verificada de monash.edu
Jason BuenrostroHarvard UniversityDirección de correo verificada de harvard.edu
Ophir ShalemUniversity of Pennsylvania / Children's Hospital of PhiladelphiaDirección de correo verificada de email.chop.edu
Jialiang HuangProfessor, Xiamen University, ChinaDirección de correo verificada de xmu.edu.cn
Giovanni ParmigianiProfessor Department of Data Science, DFCIDirección de correo verificada de dfci.harvard.edu
Semir BeyazHarvard Medical SchoolDirección de correo verificada de fas.harvard.edu
Eric LanderBroad Institute

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Luca Pinello

Associate Professor, MGH/Harvard Medical School/BROAD Institute

Dirección de correo verificada de mgh.harvard.edu - Página principal

Computational biology single cell genomics genome editing


Título Ordenar por citas Ordenar por año Ordenar por título	Citado por Citado por	Año
CRISPResso2 provides accurate and rapid genome editing sequence analysis K Clement, H Rees, MC Canver, JM Gehrke, R Farouni, JY Hsu, MA Cole, ... Nature biotechnology 37 (3), 224-226, 2019	1187	2019
Bioconda: sustainable and comprehensive software distribution for the life sciences B Grüning, R Dale, A Sjödin, BA Chapman, J Rowe, CH Tomkins-Tinch, ... Nature methods 15 (7), 475-476, 2018	1144	2018
Eleven grand challenges in single-cell data science D Lähnemann, J Köster, E Szczurek, DJ McCarthy, SC Hicks, ... Genome biology 21, 1-35, 2020	1107	2020
BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis MC Canver, EC Smith, F Sher, L Pinello, NE Sanjana, O Shalem, ... Nature 527 (7577), 192-197, 2015	966	2015
High-fat diet enhances stemness and tumorigenicity of intestinal progenitors S Beyaz, MD Mana, J Roper, D Kedrin, A Saadatpour, SJ Hong, ... Nature 531 (7592), 53-58, 2016	796	2016
An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level DE Bauer, SC Kamran, S Lessard, J Xu, Y Fujiwara, C Lin, Z Shao, ... Science 342 (6155), 253-257, 2013	709	2013
Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing BP Kleinstiver, AA Sousa, RT Walton, YE Tak, JY Hsu, K Clement, ... Nature biotechnology 37 (3), 276-282, 2019	617	2019
LincRNA-p21 regulates neointima formation, vascular smooth muscle cell proliferation, apoptosis, and atherosclerosis by enhancing p53 activity G Wu, J Cai, Y Han, J Chen, ZP Huang, C Chen, Y Cai, H Huang, Y Yang, ... Circulation 130 (17), 1452-1465, 2014	547	2014
BRCA1 recruitment to transcriptional pause sites is required for R-loop-driven DNA damage repair E Hatchi, K Skourti-Stathaki, S Ventz, L Pinello, A Yen, ... Molecular cell 57 (4), 636-647, 2015	491	2015
Highly efficient therapeutic gene editing of human hematopoietic stem cells Y Wu, J Zeng, BP Roscoe, P Liu, Q Yao, CR Lazzarotto, K Clement, ... Nature medicine 25 (5), 776-783, 2019	475	2019
An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities JM Gehrke, O Cervantes, MK Clement, Y Wu, J Zeng, DE Bauer, L Pinello, ... Nature biotechnology 36 (10), 977-982, 2018	463	2018
Analyzing CRISPR genome-editing experiments with CRISPResso L Pinello, MC Canver, MD Hoban, SH Orkin, DB Kohn, DE Bauer, ... Nature biotechnology 34 (7), 695-697, 2016	460	2016
In vivo CRISPR editing with no detectable genome-wide off-target mutations P Akcakaya, ML Bobbin, JA Guo, J Malagon-Lopez, K Clement, SP Garcia, ... Nature 561 (7723), 416-419, 2018	350	2018
Assessment of computational methods for the analysis of single-cell ATAC-seq data H Chen, C Lareau, T Andreani, ME Vinyard, SP Garcia, K Clement, ... Genome biology 20, 1-25, 2019	285	2019
GiniClust: detecting rare cell types from single-cell gene expression data with Gini index L Jiang, H Chen, L Pinello, GC Yuan Genome biology 17, 1-13, 2016	278	2016
Therapeutic base editing of human hematopoietic stem cells J Zeng, Y Wu, C Ren, J Bonanno, AH Shen, D Shea, JM Gehrke, ... Nature Medicine 26 (4), 535-541, 2020	262	2020
Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM H Chen, L Albergante, JY Hsu, CA Lareau, G Lo Bosco, J Guan, S Zhou, ... Nature communications 10 (1), 1-14, 2019	248	2019
Combinatorial assembly of developmental stage-specific enhancers controls gene expression programs during human erythropoiesis J Xu, Z Shao, K Glass, DE Bauer, L Pinello, B Van Handel, S Hou, ... Developmental cell 23 (4), 796-811, 2012	239	2012
CRISPR prime editing with ribonucleoprotein complexes in zebrafish and primary human cells K Petri, W Zhang, J Ma, A Schmidts, H Lee, JE Horng, DY Kim, IC Kurt, ... Nature biotechnology 40 (2), 189-193, 2022	178	2022
Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms H Hu, Z Piotrowska, PJ Hare, H Chen, HE Mulvey, A Mayfield, S Noeen, ... Cancer Cell 39 (11), 1531-1547. e10, 2021	167	2021

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