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Fernanda Laezza
Fernanda Laezza
Professor of Pharmacology & Toxicology, University of Texas Medical Branch
Dirección de correo verificada de utmb.edu
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Fibroblast growth factor 14 is an intracellular modulator of voltage‐gated sodium channels
JY Lou, F Laezza, BR Gerber, M Xiao, KA Yamada, H Hartmann, ...
The Journal of physiology 569 (1), 179-193, 2005
2062005
Long-term depression in hippocampal interneurons: joint requirement for pre-and postsynaptic events
F Laezza, JJ Doherty, R Dingledine
Science 285 (5432), 1411-1414, 1999
2011999
The FGF14F145S mutation disrupts the interaction of FGF14 with voltage-gated Na+ channels and impairs neuronal excitability
F Laezza, BR Gerber, JY Lou, MA Kozel, H Hartman, AM Craig, DM Ornitz, ...
Journal of Neuroscience 27 (44), 12033-12044, 2007
1612007
Crystal structure of a fibroblast growth factor homologous factor (FHF) defines a conserved surface on FHFs for binding and modulation of voltage-gated sodium channels
R Goetz, K Dover, F Laezza, N Shtraizent, X Huang, D Tchetchik, ...
Journal of biological chemistry 284 (26), 17883-17896, 2009
1552009
FGF14 N-terminal splice variants differentially modulate Nav1. 2 and Nav1. 6-encoded sodium channels
F Laezza, A Lampert, MA Kozel, BR Gerber, AM Rush, JM Nerbonne, ...
Molecular and Cellular Neuroscience 42 (2), 90-101, 2009
1442009
Dysregulated phosphorylation of Ca2+/calmodulin‐dependent protein kinase II‐α in the hippocampus of subjects with mild cognitive impairment and Alzheimer’s …
LC Reese, F Laezza, R Woltjer, G Taglialatela
Journal of neurochemistry 119 (4), 791-804, 2011
1082011
The fibroblast growth factor 14· voltage-gated sodium channel complex is a new target of glycogen synthase kinase 3 (GSK3)
AS Shavkunov, NC Wildburger, MN Nenov, TF James, TP Buzhdygan, ...
Journal of Biological Chemistry 288 (27), 19370-19385, 2013
1002013
Impaired hippocampal synaptic transmission and plasticity in mice lacking fibroblast growth factor 14
M Xiao, L Xu, F Laezza, K Yamada, S Feng, DM Ornitz
Molecular and Cellular Neuroscience 34 (3), 366-377, 2007
912007
Intraneuronal Aβ accumulation induces hippocampal neuron hyperexcitability through A-type K+ current inhibition mediated by activation of caspases and GSK-3
F Scala, S Fusco, C Ripoli, R Piacentini, DDL Puma, M Spinelli, F Laezza, ...
Neurobiology of aging 36 (2), 886-900, 2015
892015
KRIP6: a novel BTB/kelch protein regulating function of kainate receptors
F Laezza, TJ Wilding, S Sequeira, F Coussen, XZ Zhang, R Hill-Robinson, ...
Molecular and Cellular Neuroscience 34 (4), 539-550, 2007
792007
Cognitive enhancing treatment with a PPARγ agonist normalizes dentate granule cell presynaptic function in Tg2576 APP mice
MN Nenov, F Laezza, SJ Haidacher, Y Zhao, RG Sadygov, JM Starkey, ...
Journal of Neuroscience 34 (3), 1028-1036, 2014
712014
Intracellular fibroblast growth factor 14: emerging risk factor for brain disorders
J Di Re, PA Wadsworth, F Laezza
Frontiers in Cellular Neuroscience 11, 103, 2017
662017
Glycogen synthase kinase 3 beta alters anxiety-, depression-, and addiction-related behaviors and neuronal activity in the nucleus accumbens shell
EJ Crofton, MN Nenov, Y Zhang, F Scala, SA Page, DL McCue, D Li, ...
Neuropharmacology 117, 49-60, 2017
632017
Quantitative proteomics reveals protein–protein interactions with fibroblast growth factor 12 as a component of the voltage-gated sodium channel 1.2 (Nav1. 2) macromolecular …
NC Wildburger, SR Ali, WCJ Hsu, AS Shavkunov, MN Nenov, CF Lichti, ...
Molecular & Cellular Proteomics 14 (5), 1288-1300, 2015
582015
Identifying a kinase network regulating FGF14: Nav1. 6 complex assembly using split-luciferase complementation
WC Hsu, MN Nenov, A Shavkunov, N Panova, M Zhan, F Laezza
PloS one 10 (2), e0117246, 2015
552015
Voltage-controlled plasticity at GluR2-deficient synapses onto hippocampal interneurons
F Laezza, R Dingledine
Journal of neurophysiology 92 (6), 3575-3581, 2004
532004
Control of neuronal ion channel function by glycogen synthase kinase-3: new prospective for an old kinase
NC Wildburger, F Laezza
Frontiers in molecular neuroscience 5, 80, 2012
522012
Bioluminescence methodology for the detection of protein–protein interactions within the voltage-gated sodium channel macromolecular complex
A Shavkunov, N Panova, A Prasai, R Veselenak, N Bourne, ...
Assay and drug development technologies 10 (2), 148-160, 2012
502012
Peptide inhibitors disrupt the serotonin 5-HT2C receptor interaction with phosphatase and tensin homolog to allosterically modulate cellular signaling and behavior
NC Anastasio, SR Gilbertson, MJ Bubar, A Agarkov, SJ Stutz, Y Jeng, ...
Journal of Neuroscience 33 (4), 1615-1630, 2013
492013
Environmental enrichment and social isolation mediate neuroplasticity of medium spiny neurons through the GSK3 pathway
F Scala, MN Nenov, EJ Crofton, AK Singh, O Folorunso, Y Zhang, ...
Cell reports 23 (2), 555-567, 2018
472018
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