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Lacramioara Bintu
Lacramioara Bintu
Assistant Professor of Bioengineering at Stanford University
Dirección de correo verificada de stanford.edu - Página principal
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Transcriptional regulation by the numbers: models
L Bintu, NE Buchler, HG Garcia, U Gerland, T Hwa, J Kondev, R Phillips
Current opinion in genetics & development 15 (2), 116-124, 2005
9702005
Transcriptional regulation by the numbers: applications
L Bintu, NE Buchler, HG Garcia, U Gerland, T Hwa, J Kondev, T Kuhlman, ...
Current opinion in genetics & development 15 (2), 125-135, 2005
4902005
Dynamics of epigenetic regulation at the single-cell level
L Bintu
Science 351 (6274), 720-724, 2016
4612016
Nucleosomal fluctuations govern the transcription dynamics of RNA polymerase II
C Hodges, L Bintu, L Lubkowska, M Kashlev, C Bustamante
Science 325 (5940), 626-628, 2009
4512009
Nucleosomal elements that control the topography of the barrier to transcription
L Bintu, T Ishibashi, M Dangkulwanich, YY Wu, L Lubkowska, M Kashlev, ...
Cell 151 (4), 738-749, 2012
2172012
The elongation rate of RNA polymerase determines the fate of transcribed nucleosomes
L Bintu, M Kopaczynska, C Hodges, L Lubkowska, M Kashlev, ...
Nature structural & molecular biology 18 (12), 1394-1399, 2011
1672011
Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome
MG Durrant, A Fanton, J Tycko, M Hinks, SS Chandrasekaran, NT Perry, ...
Nature biotechnology 41 (4), 488-499, 2023
1342023
Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements
J Tycko, M Wainberg, GK Marinov, O Ursu, GT Hess, BK Ego, Aradhana, ...
Nature communications 10 (1), 4063, 2019
1262019
Nascent RNA structure modulates the transcriptional dynamics of RNA polymerases
B Zamft, L Bintu, T Ishibashi, C Bustamante
Proceedings of the National Academy of Sciences 109 (23), 8948-8953, 2012
1242012
High-throughput discovery and characterization of human transcriptional effectors
J Tycko, N DelRosso, GT Hess, A Banerjee, A Mukund, MV Van, BK Ego, ...
Cell 183 (7), 2020
1142020
Molecular mechanisms of transcription through single-molecule experiments
M Dangkulwanich, T Ishibashi, L Bintu, C Bustamante
Chemical reviews 114 (6), 3203-3223, 2014
1072014
The sound of silence: Transgene silencing in mammalian cell engineering
A Cabrera, HI Edelstein, F Glykofrydis, KS Love, S Palacios, J Tycko, ...
Cell Systems 13 (12), 950-973, 2022
912022
Large-scale mapping and mutagenesis of human transcriptional effector domains
N DelRosso, J Tycko, P Suzuki, C Andrews, Aradhana, A Mukund, ...
Nature 616 (7956), 365-372, 2023
852023
Mapping chromatin modifications at the single cell level
CH Ludwig, L Bintu, A Klein, B Treutlein
Development 146 (12), 2019
602019
Spatial and temporal organization of the genome: Current state and future aims of the 4D nucleome project
J Dekker, F Alber, S Aufmkolk, BJ Beliveau, BG Bruneau, AS Belmont, ...
Molecular cell, 2023
562023
Nanobody-mediated control of gene expression and epigenetic memory
MV Van, T Fujimori, L Bintu
Nature Communications 12 (1), 537, 2021
412021
Dynamic spreading of chromatin-mediated gene silencing and reactivation between neighboring genes in single cells
S Lensch, MH Herschl, CH Ludwig, J Sinha, MM Hinks, A Mukund, ...
Elife 11, e75115, 2022
262022
High-throughput functional characterization of combinations of transcriptional activators and repressors
AX Mukund, J Tycko, SJ Allen, SA Robinson, C Andrews, J Sinha, ...
Cell Systems 14 (9), 746-763. e5, 2023
232023
High-throughput discovery and characterization of viral transcriptional effectors in human cells
CH Ludwig, AR Thurm, DW Morgens, KJ Yang, J Tycko, MC Bassik, ...
Cell Systems 14 (6), 482-500. e8, 2023
192023
Development of compact transcriptional effectors using high-throughput measurements in diverse contexts
J Tycko, MV Van, Aradhana, N DelRosso, H Ye, D Yao, R Valbuena, ...
Nature Biotechnology, 1-14, 2024
162024
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