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Pedro Borralho
Pedro Borralho
Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, University of Lisbon
Dirección de correo verificada de ff.ulisboa.pt
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Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states
AL Sarver, AJ French, PM Borralho, V Thayanithy, AL Oberg, ...
BMC cancer 9, 1-15, 2009
3912009
miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease
RE Castro, DMS Ferreira, MB Afonso, PM Borralho, MV Machado, ...
Journal of hepatology 58 (1), 119-125, 2013
3822013
Delivering the promise of miRNA cancer therapeutics
DM Pereira, PM Rodrigues, PM Borralho, CMP Rodrigues
Drug discovery today 18 (5-6), 282-289, 2013
3512013
MicroRNA‐143 reduces viability and increases sensitivity to 5‐fluorouracil in HCT116 human colorectal cancer cells
PM Borralho, BT Kren, RE Castro, IB Moreira da Silva, CJ Steer, ...
The FEBS journal 276 (22), 6689-6700, 2009
2562009
miRNA expression in colon polyps provides evidence for a multihit model of colon cancer
AL Oberg, AJ French, AL Sarver, S Subramanian, BW Morlan, SM Riska, ...
PloS one 6 (6), e20465, 2011
1872011
miR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in mice
PM Rodrigues, MB Afonso, AL Simão, CC Carvalho, A Trindade, A Duarte, ...
Cell death & disease 8 (4), e2748-e2748, 2017
1322017
Efficient recovery of proteins from multiple source samples after trizol® or trizol®LS RNA extraction and long-term storage
AES Simões, DM Pereira, JD Amaral, AF Nunes, SE Gomes, ...
BMC genomics 14, 1-15, 2013
1292013
miR-143 overexpression impairs growth of human colon carcinoma xenografts in mice with induction of apoptosis and inhibition of proliferation
PM Borralho, AES Simoes, SE Gomes, RT Lima, T Carvalho, ...
PloS one 6 (8), e23787, 2011
1272011
Identification of microRNAs during rat liver regeneration after partial hepatectomy and modulation by ursodeoxycholic acid
RE Castro, DMS Ferreira, X Zhang, PM Borralho, AL Sarver, Y Zeng, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 299 (4 …, 2010
1192010
KRAS oncogene repression in colon cancer cell lines by G-quadruplex binding indolo[3,2-c]quinolines
J Lavrado, H Brito, PM Borralho, SA Ohnmacht, NS Kim, C Leitão, S Pisco, ...
Scientific reports 5 (1), 9696, 2015
972015
Cobalt complexes bearing scorpionate ligands: synthesis, characterization, cytotoxicity and DNA cleavage
TFS Silva, LM Martins, MFCG da Silva, AR Fernandes, A Silva, ...
Dalton Transactions 41 (41), 12888-12897, 2012
952012
The MEK5/ERK5 signalling pathway in cancer: a promising novel therapeutic target
AES Simoes, CMP Rodrigues, PM Borralho
Drug discovery today 21 (10), 1654-1663, 2016
932016
Cyclopentadienyl–ruthenium (II) and iron (II) organometallic compounds with carbohydrate derivative ligands as good colorectal anticancer agents
PR Florindo, DM Pereira, PM Borralho, CMP Rodrigues, MFM Piedade, ...
Journal of Medicinal Chemistry 58 (10), 4339-4347, 2015
922015
Nuclear translocation of UDCA by the glucocorticoid receptor is required to reduce TGF‐β1–induced apoptosis in rat hepatocytes
S Solá, JD Amaral, RE Castro, RM Ramalho, PM Borralho, BT Kren, ...
Hepatology 42 (4), 925-934, 2005
922005
c-Jun N-terminal kinase 1/c-Jun activation of the p53/microRNA 34a/sirtuin 1 pathway contributes to apoptosis induced by deoxycholic acid in rat liver
DMS Ferreira, MB Afonso, PM Rodrigues, AL Simão, DM Pereira, ...
Molecular and cellular biology 34 (6), 1100-1120, 2014
882014
Tauroursodeoxycholic acid modulates p53‐mediated apoptosis in Alzheimer's disease mutant neuroblastoma cells
RM Ramalho, PM Borralho, RE Castro, S Solá, CJ Steer, CMP Rodrigues
Journal of neurochemistry 98 (5), 1610-1618, 2006
872006
Inhibition of Fas expression by RNAi modulates 5-fluorouracil-induced apoptosis in HCT116 cells expressing wild-type p53
PM Borralho, IBM da Silva, MM Aranha, C Albuquerque, CN Leitão, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1772 (1), 40-47, 2007
712007
Functional modulation of nuclear steroid receptors by tauroursodeoxycholic acid reduces amyloid β-peptide-induced apoptosis
S Sola, JD Amaral, PM Borralho, RM Ramalho, RE Castro, MM Aranha, ...
Molecular endocrinology 20 (10), 2292-2303, 2006
712006
MEK5/ERK5 signaling inhibition increases colon cancer cell sensitivity to 5-fluorouracil through a p53-dependent mechanism
DM Pereira, AES Simões, SE Gomes, RE Castro, T Carvalho, ...
Oncotarget 7 (23), 34322, 2016
652016
NF‐κB and apoptosis in colorectal tumourigenesis
MM Aranha, PM Borralho, P Ravasco, IB Moreira da Silva, L Correia, ...
European journal of clinical investigation 37 (5), 416-424, 2007
652007
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
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