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Alexandre Irrthum
Alexandre Irrthum
Breast International Group - aisbl
Dirección de correo verificada de bigagainstbc.org
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Inferring regulatory networks from expression data using tree-based methods
VA Huynh-Thu, A Irrthum, L Wehenkel, P Geurts
PloS one 5 (9), e12776, 2010
19572010
Wisdom of crowds for robust gene network inference
D Marbach, JC Costello, R Küffner, NM Vega, RJ Prill, DM Camacho, ...
Nature methods 9 (8), 796-804, 2012
18572012
Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B
S Hanks, K Coleman, S Reid, A Plaja, H Firth, D FitzPatrick, A Kidd, ...
Nature genetics 36 (11), 1159-1161, 2004
7182004
Clinical management of breast cancer heterogeneity
D Zardavas, A Irrthum, C Swanton, M Piccart
Nature reviews Clinical oncology 12 (7), 381-394, 2015
5942015
Congenital hereditary lymphedema caused by a mutation that inactivates VEGFR3 tyrosine kinase
A Irrthum, MJ Karkkainen, K Devriendt, K Alitalo, M Vikkula
The American Journal of Human Genetics 67 (2), 295-301, 2000
5172000
Mutations in the transcription factor gene SOX18 underlie recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia
A Irrthum, K Devriendt, D Chitayat, G Matthijs, C Glade, PM Steijlen, ...
The American Journal of Human Genetics 72 (6), 1470-1478, 2003
4892003
Genotype-phenotype associations in Sotos syndrome: an analysis of 266 individuals with NSD1 aberrations
K Tatton-Brown, J Douglas, K Coleman, G Baujat, TRP Cole, S Das, ...
The American Journal of Human Genetics 77 (2), 193-204, 2005
3772005
Supervised learning with decision tree-based methods in computational and systems biology
P Geurts, A Irrthum, L Wehenkel
Molecular Biosystems 5 (12), 1593-1605, 2009
2802009
A gene for inherited cutaneous venous anomalies (“glomangiomas”) localizes to chromosome 1p21-22
LM Boon, P Brouillard, A Irrthum, L Karttunen, ML Warman, R Rudolph, ...
The American Journal of Human Genetics 65 (1), 125-133, 1999
1941999
MicroRNAs profiling in murine models of acute and chronic asthma: a relationship with mRNAs targets
N Garbacki, E Di Valentin, VA Huynh-Thu, P Geurts, A Irrthum, C Crahay, ...
PloS one 6 (1), e16509, 2011
1822011
Hereditary cutaneomucosal venous malformations are caused by TIE2 mutations with widely variable hyper-phosphorylating effects
V Wouters, N Limaye, M Uebelhoer, A Irrthum, LM Boon, JB Mulliken, ...
European Journal of Human Genetics 18 (4), 414-420, 2010
1812010
Genomic and transcriptomic analyses of breast cancer primaries and matched metastases in AURORA, the Breast International Group (BIG) molecular screening initiative
P Aftimos, M Oliveira, A Irrthum, D Fumagalli, C Sotiriou, EN Gal-Yam, ...
Cancer discovery 11 (11), 2796-2811, 2021
1172021
Mutations in the VEGFR3 signaling pathway explain 36% of familial lymphedema
A Mendola, MJ Schlögel, A Ghalamkarpour, A Irrthum, HL Nguyen, ...
Molecular syndromology 4 (6), 257-266, 2013
1102013
The AURORA initiative for metastatic breast cancer
D Zardavas, M Maetens, A Irrthum, T Goulioti, K Engelen, D Fumagalli, ...
British journal of cancer 111 (10), 1881-1887, 2014
1022014
Identification of a microRNA landscape targeting the PI3K/Akt signaling pathway in inflammation-induced colorectal carcinogenesis
C Josse, N Bouznad, P Geurts, A Irrthum, VA Huynh-Thu, L Servais, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 306 (3 …, 2014
862014
Multiple mechanisms are implicated in the generation of 5q35 microdeletions in Sotos syndrome
K Tatton-Brown, J Douglas, K Coleman, G Baujat, K Chandler, A Clarke, ...
Journal of medical genetics 42 (4), 307-313, 2005
832005
Myelin-derived lipids modulate macrophage activity by liver X receptor activation
JFJ Bogie, S Timmermans, VA Huynh-Thu, A Irrthum, HJM Smeets, ...
Public Library of Science 7 (9), e44998, 2012
762012
Partial NSD1 deletions cause 5% of Sotos syndrome and are readily identifiable by multiplex ligation dependent probe amplification
J Douglas, K Tatton-Brown, K Coleman, S Guerrero, J Berg, TRP Cole, ...
Journal of Medical Genetics 42 (9), e56-e56, 2005
562005
Linkage disequilibrium narrows locus for venous malformation with glomus cells (VMGLOM) to a single 1.48 Mbp YAC
A Irrthum, P Brouillard, O Enjolras, NF Gibbs, LF Eichenfield, BR Olsen, ...
European Journal of Human Genetics 9 (1), 34-38, 2001
442001
Genomic and transcriptomic analyses of breast cancer primaries and matched metastases in AURORA, the Breast International Group (BIG) molecular screening initiative. Cancer …
P Aftimos, M Oliveira, A Irrthum, D Fumagalli, C Sotiriou, EN Gal-Yam, ...
DOI: https://doi. org/10.1158/2159-8290. CD-20-1647. PMID: https://www. ncbi …, 0
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