| Dynamic changes in pro-and anti-inflammatory cytokines in microglia after PPAR-γ agonist neuroprotective treatment in the MPTPp mouse model of progressive Parkinson's disease A Pisanu, D Lecca, G Mulas, J Wardas, G Simbula, S Spiga, AR Carta Neurobiology of disease 71, 280-291, 2014 | 285 | 2014 |
| Differential induction of dyskinesia and neuroinflammation by pulsatile versus continuous l-DOPA delivery in the 6-OHDA model of Parkinson's disease G Mulas, E Espa, S Fenu, S Spiga, G Cossu, E Pillai, E Carboni, ... Experimental neurology 286, 83-92, 2016 | 95 | 2016 |
| Role of chronic neuroinflammation in neuroplasticity and cognitive function: A hypothesis D Lecca, YJ Jung, MT Scerba, I Hwang, YK Kim, S Kim, S Modrow, ... Alzheimer's & Dementia 18 (11), 2327-2340, 2022 | 66 | 2022 |
| Post-treatment with PT302, a long-acting Exendin-4 sustained release formulation, reduces dopaminergic neurodegeneration in a 6-Hydroxydopamine rat model of Parkinson’s disease S Chen, SJ Yu, Y Li, D Lecca, E Glotfelty, HK Kim, HI Choi, BJ Hoffer, ... Scientific Reports 8 (1), 10722, 2018 | 55 | 2018 |
| Boosting phagocytosis and anti‐inflammatory phenotype in microglia mediates neuroprotection by PPARγ agonist MDG548 in Parkinson's disease models D Lecca, E Janda, G Mulas, A Diana, C Martino, F Angius, S Spolitu, ... British journal of pharmacology 175 (16), 3298-3314, 2018 | 49 | 2018 |
| Neuroprotective and anti-inflammatory properties of a novel non-thiazolidinedione PPARγ agonist in vitro and in MPTP-treated mice D Lecca, DK Nevin, G Mulas, MA Casu, A Diana, D Rossi, G Sacchetti, ... Neuroscience 302, 23-35, 2015 | 48 | 2015 |
| (-)-Phenserine and the prevention of pre-programmed cell death and neuroinflammation in mild traumatic brain injury and Alzheimer's disease challenged mice D Lecca, M Bader, D Tweedie, AF Hoffman, YJ Jung, SC Hsueh, BJ Hoffer, ... Neurobiology of disease 130, 104528, 2019 | 39 | 2019 |
| 3, 6’-dithiopomalidomide reduces neural loss, inflammation, behavioral deficits in brain injury and microglial activation CT Lin, D Lecca, LY Yang, W Luo, MT Scerba, D Tweedie, PS Huang, ... Elife 9, e54726, 2020 | 30 | 2020 |
| Pharmacokinetics and efficacy of PT302, a sustained-release Exenatide formulation, in a murine model of mild traumatic brain injury M Bader, Y Li, D Lecca, V Rubovitch, D Tweedie, E Glotfelty, L Rachmany, ... Neurobiology of disease 124, 439-453, 2019 | 28 | 2019 |
| Microglia drive pockets of neuroinflammation in middle age EN Moca, D Lecca, KT Hope, F Etienne, AW Schaler, K Espinoza, ... Journal of Neuroscience 42 (19), 3896-3918, 2022 | 19 | 2022 |
| (-)-Phenserine ameliorates contusion volume, neuroinflammation, and behavioral impairments induced by traumatic brain injury in mice SC Hsueh, D Lecca, NH Greig, JY Wang, W Selman, BJ Hoffer, JP Miller, ... Cell Transplantation 28 (9-10), 1183-1196, 2019 | 14 | 2019 |
| (−)‐Phenserine tartrate (PhenT) as a treatment for traumatic brain injury NH Greig, D Lecca, SC Hsueh, C Nogueras‐Ortiz, D Kapogiannis, ... CNS Neuroscience & Therapeutics 26 (6), 636-649, 2020 | 13 | 2020 |
| 3, 6′-dithiopomalidomide ameliorates hippocampal neurodegeneration, microgliosis and astrogliosis and improves cognitive behaviors in rats with a moderate traumatic brain injury PS Huang, PY Tsai, LY Yang, D Lecca, W Luo, DS Kim, BJ Hoffer, ... International journal of molecular sciences 22 (15), 8276, 2021 | 10 | 2021 |
| Novel, thalidomide-like, non-cereblon binding drug tetrafluorobornylphthalimide mitigates inflammation and brain injury D Lecca, SC Hsueh, W Luo, D Tweedie, DS Kim, AM Baig, N Vargesson, ... Journal of biomedical science 30 (1), 16, 2023 | 5 | 2023 |
| Activity of a Novel Anti-Inflammatory Agent F-3, 6′-dithiopomalidomide as a Treatment for Traumatic Brain Injury SC Hsueh, MT Scerba, D Tweedie, D Lecca, DS Kim, AM Baig, YK Kim, ... Biomedicines 10 (10), 2449, 2022 | 5 | 2022 |
| 3, 6′-and 1, 6′-Dithiopomalidomide Mitigate Ischemic Stroke in Rats and Blunt Inflammation YR Tsai, DS Kim, SC Hsueh, KY Chen, JCC Wu, JY Wang, YS Tsou, ... Pharmaceutics 14 (5), 950, 2022 | 3 | 2022 |
| Targeting neuroinflammation reduces synaptic, neuronal and cognitive loss in 5xFAD Alzheimer mice. D Lecca, YJ Yung, MT Scerba, D Tweedie, SC Hsueh, B Hoffer, DS Kim, ... Alzheimer's & Dementia 18, e061558, 2022 | 1 | 2022 |
| Thionated aminofluorophthalimides reduce classical markers of cellular inflammation in LPS-challenged RAW 264.7 cells MT Scerba, D Tweedie, D Lecca, MA Siegler, R Rais, NH Greig Bioorganic & medicinal chemistry letters 76, 128972, 2022 | 1 | 2022 |
| Modulation of ERK1/MAPK3 potentiates ERK nuclear signalling, facilitates neuronal cell survival and improves memory in mouse models of neurodegenerative disorders M Indrigo, I Morella, D Orellana, R d’Isa, A Papale, R Parra, A Gurgone, ... bioRxiv, 496141, 2018 | 1 | 2018 |
| Mitigating chronic neuroinflammation in Alzheimer mice by novel immunomodulatory imide drugs (IMiDs) conserves neuroplasticity and cognitive function and also alleviates … NH Greig, D Lecca, SC Hsueh, D Tweedie, MT Scerba, B Hoffer, JY Wang, ... Alzheimer's & Dementia 19, e080689, 2023 | | 2023 |
