| Oncogenes and tumor angiogenesis: the HPV-16 E6 oncoprotein activates the vascular endothelial growth factor (VEGF) gene promoter in a p53 independent manner O López-Ocejo, A Viloria-Petit, M Bequet-Romero, D Mukhopadhyay, ... Oncogene 19 (40), 4611-4620, 2000 | 291 | 2000 |
| Angiogenesis modulators expression in culture cell lines positives for HPV-16 oncoproteins M Bequet-Romero, O López-Ocejo Biochemical and Biophysical Research Communications 277 (1), 55-61, 2000 | 94 | 2000 |
| A novel fusion protein-based vaccine comprising a cell penetrating and immunostimulatory peptide linked to human papillomavirus (HPV) type 16 E7 antigen generates potent … M Granadillo, MG Vallespi, A Batte, O Mendoza, Y Soria, VM Lugo, ... Vaccine 29 (5), 920-930, 2011 | 62 | 2011 |
| Specific active immunotherapy with a VEGF vaccine in patients with advanced solid tumors. Results of the CENTAURO antigen dose escalation phase I clinical trial JV Gavilondo, F Hernández-Bernal, M Ayala-Ávila, AV De La Torre, ... Vaccine 32 (19), 2241-2250, 2014 | 56 | 2014 |
| Immunogenicity and some safety features of a VEGF-based cancer therapeutic vaccine in rats, rabbits and non-human primates Y Morera, M Bequet-Romero, M Ayala, JC Velazco, PP Pérez, JS Alba, ... Vaccine 28 (19), 3453-3461, 2010 | 48 | 2010 |
| Anti-tumoral effect of active immunotherapy in C57BL/6 mice using a recombinant human VEGF protein as antigen and three chemically unrelated adjuvants Y Morera, M Bequet-Romero, M Ayala, H Lamdán, EM Agger, P Andersen, ... Angiogenesis 11, 381-393, 2008 | 48 | 2008 |
| An engineered SARS-CoV-2 receptor-binding domain produced in Pichia pastoris as a candidate vaccine antigen M Limonta-Fernández, G Chinea-Santiago, AM Martín-Dunn, ... New Biotechnology 72, 11-21, 2022 | 40 | 2022 |
| CIGB-258, a peptide derived from human heat-shock protein 60, decreases hyperinflammation in COVID-19 patients M Hernandez-Cedeño, R Venegas-Rodriguez, R Peña-Ruiz, ... Cell Stress and Chaperones 26 (3), 515-525, 2021 | 36 | 2021 |
| CIGB-247: a VEGF-based therapeutic vaccine that reduces experimental and spontaneous lung metastasis of C57Bl/6 and BALB/c mouse tumors M Bequet-Romero, Y Morera, M Ayala-Ávila, J Ancizar, Y Soria, A Blanco, ... Vaccine 30 (10), 1790-1799, 2012 | 36 | 2012 |
| Systemic translation of locally infiltrated epidermal growth factor in diabetic lower extremity wounds A García‐Ojalvo, J Berlanga Acosta, A Figueroa‐Martínez, ... International Wound Journal 16 (6), 1294-1303, 2019 | 34 | 2019 |
| Prophylactic naked DNA vaccination with the human vascular endothelial growth factor induces an anti-tumor response in C57Bl/6 mice M Bequet-Romero, M Ayala, BE Acevedo, EG Rodríguez, O López Ocejo, ... Angiogenesis 10, 23-34, 2007 | 31 | 2007 |
| Specific humoral and cellular immune responses in cancer patients undergoing chronic immunization with a VEGF-based therapeutic vaccine Y Morera, J Sánchez, M Bequet-Romero, KH Selman-Housein, ... Vaccine 35 (28), 3582-3590, 2017 | 30 | 2017 |
| Antigen dose escalation study of a VEGF-based therapeutic cancer vaccine in non human primates Y Morera, M Bequet-Romero, M Ayala, PP Pérez, J Castro, J Sánchez, ... Vaccine 30 (2), 368-377, 2012 | 30 | 2012 |
| Active antiangiogenic therapy MB Romero, BEA Castro, JVG Cowley, LEF Molina, OL Ocejo, ... US Patent 7,556,809, 2009 | 30 | 2009 |
| A multivalent recombinant antibody fragment specific for carcinoembryonic antigen L Perez, M Ayala, G Pimentel, H Bell, L Canaán‐Haden, M Bequet, ... Biotechnology and applied biochemistry 43 (1), 39-48, 2006 | 24 | 2006 |
| Effect and safety of combination of interferon alpha-2b and gamma or interferon alpha-2b for negativization of SARS-CoV-2 viral RNA. Preliminary results of a randomized … EM Idelsis, PE Jesus, DR Yaquelin, VB Dania, BR Monica, BR Lisandra, ... | 22 | 2020 |
| In-solution buffer-free digestion allows full-sequence coverage and complete characterization of post-translational modifications of the receptor-binding domain of SARS-CoV-2 … LA Espinosa, Y Ramos, I Andújar, EO Torres, G Cabrera, A Martín, ... Analytical and Bioanalytical Chemistry 413 (30), 7559-7585, 2021 | 19* | 2021 |
| Biologically active vascular endothelial growth factor as a bacterial recombinant glutathione S‐transferase fusion protein Y Morera, H Lamdan, M Bequet, M Ayala, G Rojas, Y Muñoz, ... Biotechnology and applied biochemistry 44 (1), 45-53, 2006 | 19 | 2006 |
| Expression, purification and characterization of a recombinant fusion protein based on the human papillomavirus-16 E7 antigen M Granadillo, A Batte, VM Lugo, A Musacchio, M Bequet-Romero, ... Springerplus 2, 1-8, 2013 | 18 | 2013 |
| Péptido inmunomodulador CIGB-258 para el tratamiento de pacientes graves y críticos con la COVID-19 R Venegas Rodríguez, R Peña Ruiz, R Santana Sánchez, ... Revista Cubana de Medicina Militar 49 (4), 2020 | 15 | 2020 |
Yanelys MoreraHead of Cancer Immunotherpy Laboratory, CIGBVerified email at cigb.edu.cu
