David Holtzman
David Holtzman
Dirección de correo verificada de neuro.wustl.edu
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The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic …
MS Albert, ST DeKosky, D Dickson, B Dubois, HH Feldman, NC Fox, ...
Alzheimer's & dementia 7 (3), 270-279, 2011
66502011
Inflammation and Alzheimer’s disease
H Akiyama, S Barger, S Barnum, B Bradt, J Bauer, GM Cole, NR Cooper, ...
Neurobiology of aging 21 (3), 383-421, 2000
44842000
Clinical and biomarker changes in dominantly inherited Alzheimer's disease
RJ Bateman, C Xiong, TLS Benzinger, AM Fagan, A Goate, NC Fox, ...
N Engl J Med 367, 795-804, 2012
24272012
National Institute of Neurological Disorders and Stroke–Canadian stroke network vascular cognitive impairment harmonization standards
V Hachinski, C Iadecola, RC Petersen, MM Breteler, DL Nyenhuis, ...
Stroke 37 (9), 2220-2241, 2006
17762006
NIA‐AA research framework: toward a biological definition of Alzheimer's disease
CR Jack Jr, DA Bennett, K Blennow, MC Carrillo, B Dunn, SB Haeberlein, ...
Alzheimer's & Dementia 14 (4), 535-562, 2018
16282018
Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease
RB DeMattos, KR Bales, DJ Cummins, JC Dodart, SM Paul, DM Holtzman
Proceedings of the National Academy of Sciences 98 (15), 8850-8855, 2001
15352001
Clearance of Alzheimer’s amyloid-β1-40 peptide from brain by LDL receptor–related protein-1 at the blood-brain barrier
M Shibata, S Yamada, SR Kumar, M Calero, J Bading, B Frangione, ...
The Journal of clinical investigation 106 (12), 1489-1499, 2000
13342000
The role of apolipoprotein E in Alzheimer's disease
J Kim, JM Basak, DM Holtzman
Neuron 63 (3), 287-303, 2009
13322009
Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Aβ42 in humans
AM Fagan, MA Mintun, RH Mach, SY Lee, CS Dence, AR Shah, ...
Annals of neurology 59 (3), 512-519, 2006
12392006
Alzheimer’s disease: the challenge of the second century
DM Holtzman, JC Morris, AM Goate
Science translational medicine 3 (77), 77sr1-77sr1, 2011
11342011
Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model
JC Dodart, KR Bales, KS Gannon, SJ Greene, RB DeMattos, C Mathis, ...
Nature neuroscience 5 (5), 452-457, 2002
11112002
Synaptic activity regulates interstitial fluid amyloid-β levels in vivo
JR Cirrito, KA Yamada, MB Finn, RS Sloviter, KR Bales, PC May, ...
Neuron 48 (6), 913-922, 2005
10332005
Amyloid-β dynamics are regulated by orexin and the sleep-wake cycle
JE Kang, MM Lim, RJ Bateman, JJ Lee, LP Smyth, JR Cirrito, N Fujiki, ...
Science 326 (5955), 1005-1007, 2009
10122009
Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease
DM Holtzman, KR Bales, T Tenkova, AM Fagan, M Parsadanian, ...
Proceedings of the National Academy of Sciences 97 (6), 2892-2897, 2000
9622000
Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease
M Meyer-Luehmann, TL Spires-Jones, C Prada, M Garcia-Alloza, ...
Nature 451 (7179), 720-724, 2008
9222008
Human apoE isoforms differentially regulate brain amyloid-β peptide clearance
JM Castellano, J Kim, FR Stewart, H Jiang, RB DeMattos, BW Patterson, ...
Science translational medicine 3 (89), 89ra57-89ra57, 2011
9142011
ApoE promotes the proteolytic degradation of Aβ
Q Jiang, CYD Lee, S Mandrekar, B Wilkinson, P Cramer, N Zelcer, ...
Neuron 58 (5), 681-693, 2008
8852008
Cerebrospinal fluid tau/β-amyloid42 ratio as a prediction of cognitive decline in nondemented older adults
AM Fagan, CM Roe, C Xiong, MA Mintun, JC Morris, DM Holtzman
Archives of neurology 64 (3), 343-349, 2007
8632007
Selective vulnerability of late oligodendrocyte progenitors to hypoxia–ischemia
SA Back, BH Han, NL Luo, CA Chricton, S Xanthoudakis, J Tam, KL Arvin, ...
Journal of Neuroscience 22 (2), 455-463, 2002
8242002
Apolipoprotein E controls cerebrovascular integrity via cyclophilin A
RD Bell, EA Winkler, I Singh, AP Sagare, R Deane, Z Wu, DM Holtzman, ...
Nature 485 (7399), 512-516, 2012
7722012
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20