Joseph S. Takahashi
Joseph S. Takahashi
Department of Neuroscience, Howard Hughes Medical Institute, University of Texas Southwestern
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Coordinated transcription of key pathways in the mouse by the circadian clock
S Panda, MP Antoch, BH Miller, AI Su, AB Schook, M Straume, PG Schultz, ...
Cell 109 (3), 307-320, 2002
Obesity and metabolic syndrome in circadian Clock mutant mice
FW Turek, C Joshu, A Kohsaka, E Lin, G Ivanova, E McDearmon, ...
Science 308 (5724), 1043-1045, 2005
PERIOD2:: LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues
SH Yoo, S Yamazaki, PL Lowrey, K Shimomura, CH Ko, ED Buhr, ...
Proceedings of the National Academy of Sciences 101 (15), 5339-5346, 2004
Role of the CLOCK protein in the mammalian circadian mechanism
N Gekakis, D Staknis, HB Nguyen, FC Davis, LD Wilsbacher, DP King, ...
Science 280 (5369), 1564-1569, 1998
Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior
MH Vitaterna, DP King, AM Chang, JM Kornhauser, PL Lowrey, ...
Science 264 (5159), 719-725, 1994
Molecular components of the mammalian circadian clock
CH Ko, JS Takahashi
Human molecular genetics 15 (suppl_2), R271-R277, 2006
Positional cloning of the mouse circadian clock gene
DP King, Y Zhao, AM Sangoram, LD Wilsbacher, M Tanaka, MP Antoch, ...
Cell 89 (4), 641-653, 1997
The genetics of mammalian circadian order and disorder: implications for physiology and disease
JS Takahashi, HK Hong, CH Ko, EL McDearmon
Nature reviews genetics 9 (10), 764-775, 2008
Circadian integration of metabolism and energetics
J Bass, JS Takahashi
Science 330 (6009), 1349-1354, 2010
Mop3 is an essential component of the master circadian pacemaker in mammals
MK Bunger, LD Wilsbacher, SM Moran, C Clendenin, LA Radcliffe, ...
Cell 103 (7), 1009-1017, 2000
Central and peripheral circadian clocks in mammals
JA Mohawk, CB Green, JS Takahashi
Annual review of neuroscience 35, 445-462, 2012
Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes
B Marcheva, KM Ramsey, ED Buhr, Y Kobayashi, H Su, CH Ko, G Ivanova, ...
Nature 466 (7306), 627-631, 2010
Mammalian circadian biology: elucidating genome-wide levels of temporal organization
PL Lowrey, JS Takahashi
Annu. Rev. Genomics Hum. Genet. 5, 407-441, 2004
Suprachiasmatic nucleus: cell autonomy and network properties
DK Welsh, JS Takahashi, SA Kay
Annual review of physiology 72, 551-577, 2010
Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau
PL Lowrey, K Shimomura, MP Antoch, S Yamazaki, PD Zemenides, ...
Science 288 (5465), 483-491, 2000
Closing the circadian loop: CLOCK-induced transcription of its own inhibitors per and tim
TK Darlington, K Wager-Smith, MF Ceriani, D Staknis, N Gekakis, ...
Science 280 (5369), 1599-1603, 1998
Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis
KM Ramsey, J Yoshino, CS Brace, D Abrassart, Y Kobayashi, B Marcheva, ...
Science 324 (5927), 651-654, 2009
Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock
DD Ginty, JM Kornhauser, MA Thompson, H Bading, KE Mayo, ...
Science 260 (5105), 238-241, 1993
Transcriptional architecture and chromatin landscape of the core circadian clock in mammals
N Koike, SH Yoo, HC Huang, V Kumar, C Lee, TK Kim, JS Takahashi
Science 338 (6105), 349-354, 2012
Transcriptional architecture and chromatin landscape of the core circadian clock in mammals
N Koike, SH Yoo, HC Huang, V Kumar, C Lee, TK Kim, JS Takahashi
Science 338 (6105), 349-354, 2012
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Artículos 1–20