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Epigenetic memory in induced pluripotent stem cells K Kim, A Doi, B Wen, K Ng, R Zhao, P Cahan, J Kim, MJ Aryee, H Ji, ... Nature 467 (7313), 285-290, 2010 | 2694 | 2010 |
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Mapping the mouse cell atlas by microwell-seq X Han, R Wang, Y Zhou, L Fei, H Sun, S Lai, A Saadatpour, Z Zhou, ... Cell 172 (5), 1091-1107. e17, 2018 | 1675 | 2018 |
Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping M Gessler, A Poustka, W Cavenee, RL Neve, SH Orkin, GAP Bruns Nature 343 (6260), 774-778, 1990 | 1649 | 1990 |
Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1 L Pevny, MC Simon, E Robertson, WH Klein, SF Tsai, V D'Agati, SH Orkin, ... Nature 349 (6306), 257-260, 1991 | 1643 | 1991 |
An extended transcriptional network for pluripotency of embryonic stem cells J Kim, J Chu, X Shen, J Wang, SH Orkin Cell 132 (6), 1049-1061, 2008 | 1588 | 2008 |
A protein interaction network for pluripotency of embryonic stem cells J Wang, S Rao, J Chu, X Shen, DN Levasseur, TW Theunissen, SH Orkin Nature 444 (7117), 364-368, 2006 | 1345 | 2006 |
Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis TE North, W Goessling, CR Walkley, C Lengerke, KR Kopani, AM Lord, ... Nature 447 (7147), 1007-1011, 2007 | 1297 | 2007 |
Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL RA Shivdasani, EL Mayer, SH Orkin Nature 373 (6513), 432-434, 1995 | 1192 | 1995 |
GATA-binding transcription factors in hematopoietic cells SH Orkin Blood 80 (3), 575-581, 1992 | 1147 | 1992 |
Linkage of β-thalassaemia mutations and β-globin gene polymorphisms with DNA polymorphisms in human β-globin gene cluster SH Orkin, HH Kazazian Jr, SE Antonarakis, SC Goff, CD Boehm, ... Nature 296 (5858), 627-631, 1982 | 1134 | 1982 |
EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency X Shen, Y Liu, YJ Hsu, Y Fujiwara, J Kim, X Mao, GC Yuan, SH Orkin Molecular cell 32 (4), 491-502, 2008 | 1122 | 2008 |
Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library JF Rual, J Ceron, J Koreth, T Hao, AS Nicot, T Hirozane-Kishikawa, ... Genome research 14 (10b), 2162-2168, 2004 | 1112 | 2004 |
A critical role for eosinophils in allergic airways remodeling AA Humbles, CM Lloyd, SJ McMillan, DS Friend, G Xanthou, EE McKenna, ... Science 305 (5691), 1776-1779, 2004 | 1111 | 2004 |
Sickle cell disease RE Ware, M de Montalembert, L Tshilolo, MR Abboud The Lancet 390 (10091), 311-323, 2017 | 1080 | 2017 |
Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A VG Sankaran, TF Menne, J Xu, TE Akie, G Lettre, B Van Handel, ... Science 322 (5909), 1839-1842, 2008 | 1075 | 2008 |
Cloning the gene for an inherited human disorder—chronic granulomatous disease—on the basis of its chromosomal location B Royer-Pokora, LM Kunkel, AP Monaco, SC Goff, PE Newburger, ... Nature 322 (6074), 32-38, 1986 | 1074 | 1986 |
Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells SF Tsai, DIK Martin, LI Zon, AD D'Andrea, GG Wong, SH Orkin Nature 339 (6224), 446-451, 1989 | 1073 | 1989 |