Michele Donato
Michele Donato
Senior Bioinformatics Research Engineer, Freenome
Verified email at
Cited by
Cited by
Single-cell chromatin modification profiling reveals increased epigenetic variations with aging
P Cheung, F Vallania, HC Warsinske, M Donato, S Schaffert, SE Chang, ...
Cell 173 (6), 1385-1397. e14, 2018
Unsupervised analysis of transcriptomics in bacterial sepsis across multiple datasets reveals three robust clusters
TE Sweeney, TD Azad, M Donato, WA Haynes, TM Perumal, R Henao, ...
Critical care medicine 46 (6), 915, 2018
Methods and approaches in the topology-based analysis of biological pathways
C Mitrea, Z Taghavi, B Bokanizad, S Hanoudi, R Tagett, M Donato, ...
Frontiers in Physiology 4, 278, 2013
The single-cell epigenomic and transcriptional landscape of immunity to influenza vaccination
F Wimmers, M Donato, A Kuo, T Ashuach, S Gupta, C Li, M Dvorak, ...
Cell 184 (15), 3915-3935. e21, 2021
Analysis and correction of crosstalk effects in pathway analysis
M Donato, Z Xu, A Tomoiaga, JG Granneman, RG MacKenzie, R Bao, ...
Genome research 23 (11), 1885-1893, 2013
The immunoregulatory landscape of human tuberculosis granulomas
EF McCaffrey, M Donato, L Keren, Z Chen, A Delmastro, MB Fitzpatrick, ...
Nature immunology 23 (2), 318-329, 2022
A novel computational approach for drug repurposing using systems biology
A Peyvandipour, N Saberian, A Shafi, M Donato, S Draghici
Bioinformatics 34 (16), 2817-2825, 2018
Cellular senescence impairs the reversibility of pulmonary arterial hypertension
DE Van Der Feen, GPL Bossers, QAJ Hagdorn, JR Moonen, K Kurakula, ...
Science translational medicine 12 (554), eaaw4974, 2020
Macrophage-derived IL-6 trans-signalling as a novel target in the pathogenesis of bronchopulmonary dysplasia
D Hirani, CM Alvira, S Danopoulos, C Milla, M Donato, L Tian, J Mohr, ...
European Respiratory Journal 59 (2), 2022
Multi-cohort analysis of host immune response identifies conserved protective and detrimental modules associated with severity across viruses
H Zheng, AM Rao, D Dermadi, J Toh, LM Jones, M Donato, Y Liu, Y Su, ...
Immunity 54 (4), 753-768. e5, 2021
A new computational drug repurposing method using established disease–drug pair knowledge
N Saberian, A Peyvandipour, M Donato, S Ansari, S Draghici
Bioinformatics 35 (19), 3672-3678, 2019
FHIT, a Novel Modifier Gene in Pulmonary Arterial Hypertension
S Dannewitz Prosseda, X Tian, K Kuramoto, M Boehm, D Sudheendra, ...
American journal of respiratory and critical care medicine 199 (1), 83-98, 2019
Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation
P Cheung, S Schaffert, SE Chang, M Dvorak, M Donato, C Macaubas, ...
Nature Immunology 22 (6), 711-722, 2021
Incorporating gene significance in the impact analysis of signaling pathways
C Voichita, M Donato, S Draghici
2012 11th International Conference on Machine Learning and Applications 1 …, 2012
Cross-clustering: a partial clustering algorithm with automatic estimation of the number of clusters
P Tellaroli, M Bazzi, M Donato, AR Brazzale, S Drăghici
PloS one 11 (3), e0152333, 2016
A novel bi-level meta-analysis approach: applied to biological pathway analysis
T Nguyen, R Tagett, M Donato, C Mitrea, S Draghici
Bioinformatics 32 (3), 409-416, 2016
Single-cell epigenetics–Chromatin modification atlas unveiled by mass cytometry
P Cheung, F Vallania, M Dvorak, SE Chang, S Schaffert, M Donato, ...
Clinical Immunology 196, 40-48, 2018
The Biological Connection Markup Language: a SBGN-compliant format for visualization, filtering and analysis of biological pathways
L Beltrame, E Calura, RR Popovici, L Rizzetto, DR Guedez, M Donato, ...
Bioinformatics 27 (15), 2127-2133, 2011
Inflammatory macrophage–associated 3-gene signature predicts subclinical allograft injury and graft survival
TD Azad, M Donato, L Heylen, AB Liu, SS Shen-Orr, TE Sweeney, ...
JCI insight 3 (2), 2018
Rapid GPR183-mediated recruitment of eosinophils to the lung after Mycobacterium tuberculosis infection
AC Bohrer, E Castro, CE Tocheny, M Assmann, B Schwarz, E Bohrnsen, ...
Cell reports 40 (4), 2022
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