| High fat, high calorie diet promotes early pancreatic neoplasia in the conditional KrasG12D mouse model DW Dawson, K Hertzer, A Moro, G Donald, HH Chang, VL Go, SJ Pandol, ... Cancer prevention research, canprevres. 0065.2013, 2013 | 158 | 2013 |
| Incidence of pancreatic cancer is dramatically increased by a high fat, high calorie diet in KrasG12D mice HH Chang, A Moro, K Takakura, HY Su, A Mo, M Nakanishi, RT Waldron, ... PloS one 12 (9), e0184455, 2017 | 128 | 2017 |
| Identification and development of mPGES-1 inhibitors: where we are at? HH Chang, EJ Meuillet Future medicinal chemistry 3 (15), 1909-1934, 2011 | 120 | 2011 |
| miR-143 decreases COX-2 mRNA stability and expression in pancreatic cancer cells H Pham, CE Rodriguez, GW Donald, KM Hertzer, XS Jung, HH Chang, ... Biochemical and biophysical research communications 439 (1), 6-11, 2013 | 62 | 2013 |
| Insulin-like growth factor–1 preserves salivary gland function after fractionated radiation KH Limesand, JL Avila, K Victory, HH Chang, YJ Shin, O Grundmann, ... International Journal of Radiation Oncology* Biology* Physics 78 (2), 579-586, 2010 | 59 | 2010 |
| Insulin promotes proliferation and fibrosing responses in activated pancreatic stellate cells J Yang, RT Waldron, HY Su, A Moro, HH Chang, G Eibl, K Ferreri, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 311 (4 …, 2016 | 57 | 2016 |
| Targeting inflammation: multiple innovative ways to reduce prostaglandin E2 JK Norberg, E Sells, HH Chang, SR Alla, S Zhang, EJ Meuillet Future Science Ltd London, UK, 2013 | 55 | 2013 |
| Robust Early Inflammation of the Peri-pancreatic Visceral Adipose Tissue During Diet-Induced Obesity in the KrasG12D Model of Pancreatic Cancer KM Hertzer, M Xu, A Moro, DW Dawson, L Du, G Li, HH Chang, AP Stark, ... Pancreas 45 (3), 458, 2016 | 50 | 2016 |
| Synthesis and biological activity of 2-aminothiazoles as novel inhibitors of PGE 2 production in cells B Smith, HH Chang, F Medda, V Gokhale, J Dietrich, A Davis, EJ Meuillet, ... Bioorganic & medicinal chemistry letters 22 (10), 3567-3570, 2012 | 49 | 2012 |
| Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA-and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1 HH Chang, SH Young, J Sinnett-Smith, CEN Chou, A Moro, KM Hertzer, ... American Journal of Physiology-Cell Physiology 309 (10), C639-C649, 2015 | 30 | 2015 |
| Identification of a novel class of anti-inflammatory compounds with anti-tumor activity in colorectal and lung cancers HH Chang, Z Song, L Wisner, T Tripp, V Gokhale, EJ Meuillet Investigational new drugs 30 (5), 1865-1877, 2012 | 16 | 2012 |
| Synthesis and biological activity of aminophthalazines and aminopyridazines as novel inhibitors of PGE 2 production in cells F Medda, E Sells, HH Chang, J Dietrich, S Chappeta, B Smith, V Gokhale, ... Bioorganic & medicinal chemistry letters 23 (2), 528-531, 2013 | 15 | 2013 |
| E-cadherin expression in obesity-associated, Kras-initiated pancreatic ductal adenocarcinoma in mice AP Stark, HH Chang, X Jung, A Moro, K Hertzer, M Xu, A Schmidt, ... Surgery 158 (6), 1564-1572, 2015 | 14 | 2015 |
| Direct growth-inhibitory effects of prostaglandin E2 in pancreatic cancer cells in vitro through an EP4/PKA-mediated mechanism A Schmidt, J Sinnett-Smith, S Young, HH Chang, OJ Hines, DW Dawson, ... Surgery 161 (6), 1570-1578, 2017 | 7 | 2017 |
| Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA and EP1/calcium-mediated mechanisms in human pancreatic carcinoma cells HH Chang, S Young, J Sinnett-Smith, CEN Chou, OJ Hines, E Rozengurt, ... Cancer Research 75 (15 Supplement), 1028-1028, 2015 | 1 | 2015 |
| Models and Mechanisms of High-Fat Diet (HFD) Promotion of Pancreatic Cancer HH Chang, G Eibl, E Rozengurt Murine Models, Energy Balance, and Cancer, 197-215, 2015 | 1 | 2015 |
| Signaling cross-talks in obesity-associated pancreatic cancer: Interaction between prostaglandin E2 signaling and mTOR pathway HH Chang, G Eibl Cancer Research 74 (19 Supplement), 5291-5291, 2014 | 1 | 2014 |
| Statins Potently Inhibit YAP Activity and Proliferation of Mouse Pancreatic Cells Isolated From KC and KPC Mice F Hao, JK Chang, J Sinnett-Smith, G Eibl, HH Chang, E Rozengurt Gastroenterology 152 (5), S837, 2017 | | 2017 |
| Diet-Independent Visceral Adipose Tissue Inflammation Accelerates Pancreatic Cancer Development in the Conditional KrasG12D Mouse Model G Eibl, M Xu, X Jung, A Moro, C Chou, A Schmidt, HH Chang, OJ Hines PANCREAS 45 (10), 1503-1503, 2016 | | 2016 |
| Oncogenic KRAS and the Inflammatory Micro-Environment in Pancreatic Cancer HH Chang, A Schmidt, G Eibl Conquering RAS: From Biology to Cancer Therapy 87, 79, 2016 | | 2016 |
