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Christopher T. Saeui
Christopher T. Saeui
Department of Biomedical Engineering, Johns Hopkins University School of Medicine
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Exploiting metabolic glycoengineering to advance healthcare
C Agatemor, MJ Buettner, R Ariss, K Muthiah, CT Saeui, KJ Yarema
Nature Reviews Chemistry 3 (10), 605-620, 2019
1182019
Improving immunotherapy through glycodesign
MJ Buettner, SR Shah, CT Saeui, R Ariss, KJ Yarema
Frontiers in immunology 9, 2485, 2018
672018
Metabolic flux-driven sialylation alters internalization, recycling, and drug sensitivity of the epidermal growth factor receptor (EGFR) in SW1990 pancreatic cancer cells
MP Mathew, E Tan, CT Saeui, P Bovonratwet, S Sklar, R Bhattacharya, ...
Oncotarget 7 (41), 66491, 2016
382016
Metabolic glycoengineering sensitizes drug-resistant pancreatic cancer cells to tyrosine kinase inhibitors erlotinib and gefitinib
MP Mathew, E Tan, CT Saeui, P Bovonratwet, L Liu, R Bhattacharya, ...
Bioorganic & Medicinal Chemistry Letters 25 (6), 1223-1227, 2015
372015
Cell surface and membrane engineering: emerging technologies and applications
CT Saeui, MP Mathew, L Liu, E Urias, KJ Yarema
Journal of functional biomaterials 6 (2), 454-485, 2015
362015
Biodynamic performance of hyaluronic acid versus synovial fluid of the knee in osteoarthritis
M Corvelli, B Che, C Saeui, A Singh, J Elisseeff
Methods 84, 90-98, 2015
322015
Identification of sialylated glycoproteins from metabolically oligosaccharide engineered pancreatic cells
Y Tian, RT Almaraz, CH Choi, QK Li, C Saeui, D Li, P Shah, ...
Clinical proteomics 12, 1-13, 2015
312015
Harnessing cancer cell metabolism for theranostic applications using metabolic glycoengineering of sialic acid in breast cancer as a pioneering example
HA Badr, DMM AlSadek, ME El-Houseini, CT Saeui, MP Mathew, ...
Biomaterials 116, 158-173, 2017
302017
Combining butyrated ManNAc with glycoengineered CHO cells improves EPO glycan quality and production
Q Wang, CY Chung, W Yang, G Yang, S Chough, Y Chen, B Yin, ...
Biotechnology Journal 14 (4), 1800186, 2019
232019
Sulfamoyl benzamides as novel CB2 cannabinoid receptor ligands
K Worm, QJ Zhou, CT Saeui, RC Green, JA Cassel, GJ Stabley, ...
Bioorganic & medicinal chemistry letters 18 (9), 2830-2835, 2008
222008
Metabolic glycoengineering bacteria for therapeutic, recombinant protein, and metabolite production applications
CT Saeui, E Urias, L Liu, MP Mathew, KJ Yarema
Glycoconjugate journal 32, 425-441, 2015
212015
Improving the pharmacodynamics and in vivo activity of ENPP1‐Fc through protein and glycosylation engineering
PR Stabach, K Zimmerman, A Adame, D Kavanagh, CT Saeui, ...
Clinical and translational science 14 (1), 362-372, 2021
192021
Integration of genetic and metabolic features related to sialic acid metabolism distinguishes human breast cell subtypes
CT Saeui, AV Nairn, M Galizzi, C Douville, P Gowda, M Park, ...
PLoS One 13 (5), e0195812, 2018
192018
Novel pyridine derivatives as potent and selective CB2 cannabinoid receptor agonists
GH Chu, CT Saeui, K Worm, DG Weaver, AJ Goodman, RL Broadrup, ...
Bioorganic & medicinal chemistry letters 19 (20), 5931-5935, 2009
192009
Determination of absolute expression profiles using multiplexed miRNA analysis
Y Song, D Kilburn, JH Song, Y Cheng, CT Saeui, DG Cheung, CM Croce, ...
PLoS One 12 (7), e0180988, 2017
182017
Novel sulfamoyl benzamides as selective CB2 agonists with improved in vitro metabolic stability
I Sellitto, B Le Bourdonnec, K Worm, A Goodman, MA Savolainen, ...
Bioorganic & medicinal chemistry letters 20 (1), 387-391, 2010
182010
Discovery of N-(3-(morpholinomethyl)-phenyl)-amides as potent and selective CB2 agonists
K Worm, DG Weaver, RC Green, CT Saeui, DMS Dulay, WM Barker, ...
Bioorganic & medicinal chemistry letters 19 (17), 5004-5008, 2009
142009
Pharmacological, physiochemical, and drug-relevant biological properties of short chain fatty acid hexosamine analogues used in metabolic glycoengineering
CT Saeui, L Liu, E Urias, J Morrissette-McAlmon, R Bhattacharya, ...
Molecular pharmaceutics 15 (3), 705-720, 2017
132017
Glycoengineering of Esterase Activity through Metabolic Flux‐Based Modulation of Sialic Acid
MP Mathew, E Tan, JW Labonte, S Shah, CT Saeui, L Liu, R Bhattacharya, ...
ChemBioChem 18 (13), 1204-1215, 2017
122017
Glycoengineering Human Neural and Adipose Stem Cells with Novel Thiol-Modified N-Acetylmannosamine (ManNAc) Analogs
J Du, C Agatemor, CT Saeui, R Bhattacharya, X Jia, KJ Yarema
Cells 10 (2), 377, 2021
102021
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Artículos 1–20