| SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation MD Hirschey, T Shimazu, E Goetzman, E Jing, B Schwer, DB Lombard, ... Nature 464 (7285), 121-125, 2010 | 1800 | 2010 |
| Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor T Shimazu, MD Hirschey, J Newman, W He, K Shirakawa, N Le Moan, ... Science 339 (6116), 211-214, 2013 | 1691 | 2013 |
| Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation X Qiu, K Brown, MD Hirschey, E Verdin, D Chen Cell metabolism 12 (6), 662-667, 2010 | 1458 | 2010 |
| Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation DB Lombard, FW Alt, HL Cheng, J Bunkenborg, RS Streeper, ... Molecular and cellular biology 27 (24), 8807-8814, 2007 | 1413 | 2007 |
| SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome MD Hirschey, T Shimazu, E Jing, CA Grueter, AM Collins, B Aouizerat, ... Molecular cell 44 (2), 177-190, 2011 | 867 | 2011 |
| Lysine glutarylation is a protein posttranslational modification regulated by SIRT5 M Tan, C Peng, KA Anderson, P Chhoy, Z Xie, L Dai, J Park, Y Chen, ... Cell metabolism 19 (4), 605-617, 2014 | 796 | 2014 |
| Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling E Verdin, MD Hirschey, LWS Finley, MC Haigis Trends in biochemical sciences 35 (12), 669-675, 2010 | 724 | 2010 |
| Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production E Jing, B Emanuelli, MD Hirschey, J Boucher, KY Lee, D Lombard, ... Proceedings of the national academy of sciences 108 (35), 14608-14613, 2011 | 554 | 2011 |
| SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production T Shimazu, MD Hirschey, L Hua, KE Dittenhafer-Reed, B Schwer, ... Cell metabolism 12 (6), 654-661, 2010 | 535 | 2010 |
| Metabolic regulation by lysine malonylation, succinylation, and glutarylation MD Hirschey, Y Zhao Molecular & Cellular Proteomics 14 (9), 2308-2315, 2015 | 422 | 2015 |
| Nonenzymatic protein acylation as a carbon stress regulated by sirtuin deacylases GR Wagner, MD Hirschey Molecular cell 54 (1), 5-16, 2014 | 352 | 2014 |
| Dietary restriction and AMPK increase lifespan via mitochondrial network and peroxisome remodeling HJ Weir, P Yao, FK Huynh, CC Escoubas, RL Goncalves, K Burkewitz, ... Cell metabolism 26 (6), 884-896. e5, 2017 | 344 | 2017 |
| Lipids reprogram metabolism to become a major carbon source for histone acetylation E McDonnell, SB Crown, DB Fox, B Kitir, OR Ilkayeva, CA Olsen, ... Cell reports 17 (6), 1463-1472, 2016 | 334 | 2016 |
| Dysregulated metabolism contributes to oncogenesis MD Hirschey, RJ DeBerardinis, AME Diehl, JE Drew, C Frezza, MF Green, ... Seminars in cancer biology 35, S129-S150, 2015 | 317 | 2015 |
| Designing a broad-spectrum integrative approach for cancer prevention and treatment KI Block, C Gyllenhaal, L Lowe, A Amedei, ARMR Amin, A Amin, ... Seminars in cancer biology 35, S276-S304, 2015 | 312 | 2015 |
| Mitochondrial sirtuins JY Huang, MD Hirschey, T Shimazu, L Ho, E Verdin Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1804 (8), 1645-1651, 2010 | 312 | 2010 |
| SIRT4 is a lysine deacylase that controls leucine metabolism and insulin secretion KA Anderson, FK Huynh, K Fisher-Wellman, JD Stuart, BS Peterson, ... Cell metabolism 25 (4), 838-855. e15, 2017 | 310 | 2017 |
| The sirtuins, oxidative stress and aging: an emerging link PI Merksamer, Y Liu, W He, MD Hirschey, D Chen, E Verdin Aging (Albany NY) 5 (3), 144, 2013 | 305 | 2013 |
| SIRT3 regulates progression and development of diseases of aging E McDonnell, BS Peterson, HM Bomze, MD Hirschey Trends in Endocrinology & Metabolism 26 (9), 486-492, 2015 | 290 | 2015 |
| Mitochondrial protein acetylation regulates metabolism KA Anderson, MD Hirschey Essays in biochemistry 52, 23-35, 2012 | 280 | 2012 |
