Taurine prevents the neurotoxicity of β‐amyloid and glutamate receptor agonists: activation of GABA receptors and possible implications for Alzheimer's disease and other … PR Louzada, ACP Lima, DL Mendonca‐Silva, F Noël, FG De Mello, ... The FASEB journal 18 (3), 511-518, 2004 | 295 | 2004 |
Deregulation of excitatory neurotransmission underlying synapse failure in Alzheimer's disease AC Paula‐Lima, J Brito‐Moreira, ST Ferreira Journal of neurochemistry 126 (2), 191-202, 2013 | 213 | 2013 |
Amyloid β-Peptide Oligomers Stimulate RyR-Mediated Ca2+ Release Inducing Mitochondrial Fragmentation in Hippocampal Neurons and Prevent RyR-Mediated … AC Paula-Lima, T Adasme, C SanMartin, A Sebollela, C Hetz, ... Antioxidants & redox signaling 14 (7), 1209-1223, 2011 | 161 | 2011 |
Involvement of ryanodine receptors in neurotrophin-induced hippocampal synaptic plasticity and spatial memory formation T Adasme, P Haeger, AC Paula-Lima, I Espinoza, MM Casas-Alarcón, ... Proceedings of the National Academy of Sciences 108 (7), 3029-3034, 2011 | 150 | 2011 |
Human apolipoprotein A–I binds amyloid-β and prevents Aβ-induced neurotoxicity AC Paula-Lima, MA Tricerri, J Brito-Moreira, TR Bomfim, FF Oliveira, ... The international journal of biochemistry & cell biology 41 (6), 1361-1370, 2009 | 143 | 2009 |
Activation of GABAA receptors by taurine and muscimol blocks the neurotoxicity of β-amyloid in rat hippocampal and cortical neurons AC Paula-Lima, FG De Felice, J Brito-Moreira, ST Ferreira Neuropharmacology 49 (8), 1140-1148, 2005 | 116 | 2005 |
Aβ oligomers induce glutamate release from hippocampal neurons J Brito-Moreira, A C Paula-Lima, T R Bomfim, F F Oliveira, F J Sepulveda, ... Current Alzheimer Research 8 (5), 552-562, 2011 | 112 | 2011 |
Amyloid-β oligomers induce differential gene expression in adult human brain slices A Sebollela, L Freitas-Correa, FF Oliveira, AC Paula-Lima, LM Saraiva, ... Journal of Biological Chemistry 287 (10), 7436-7445, 2012 | 105 | 2012 |
Contribution of Ca2+ release channels to hippocampal synaptic plasticity and spatial memory: potential redox modulation. HC Paula-Lima AC, Adasme T Antioxid Redox Signal. 21 (6), 892-914, 2014 | 75 | 2014 |
Nicotinamide, a poly [ADP-ribose] polymerase 1 (PARP-1) inhibitor, as an adjunctive therapy for the treatment of Alzheimer’s disease F Salech, DP Ponce, AC Paula-Lima, CD SanMartin, MI Behrens Frontiers in Aging Neuroscience 12, 255, 2020 | 73 | 2020 |
Astaxanthin protects primary hippocampal neurons against noxious effects of Aβ-oligomers P Lobos, B Bruna, A Cordova, P Barattini, JL Galáz, T Adasme, C Hidalgo, ... Neural plasticity 2016, 2016 | 69 | 2016 |
Neuroprotection against Aβ and glutamate toxicity by melatonin: Are GABA receptors involved? ACP Lima, PR Louzada, FG De Mello, ST Ferreira Neurotoxicity research 5, 323-327, 2003 | 68 | 2003 |
Alzheimer’s disease-like pathology triggered by Porphyromonas gingivalis in wild type rats is serotype dependent J Díaz-Zúñiga, J More, S Melgar-Rodríguez, M Jiménez-Unión, ... Frontiers in immunology 11, 588036, 2020 | 63 | 2020 |
Serotype b of Aggregatibacter actinomycetemcomitans triggers pro-inflammatory responses and amyloid beta secretion in hippocampal cells: a novel link between … J Díaz-Zúñiga, Y Muñoz, S Melgar-Rodríguez, J More, B Bruna, P Lobos, ... Journal of oral microbiology 11 (1), 1586423, 2019 | 58 | 2019 |
The signaling pathways underlying BDNF-induced Nrf2 hippocampal nuclear translocation involve ROS, RyR-Mediated Ca2+ signals, ERK and PI3K B Bruna, P Lobos, R Herrera-Molina, C Hidalgo, A Paula-Lima, T Adasme Biochemical and biophysical research communications 505 (1), 201-207, 2018 | 56 | 2018 |
N-acetylcysteine prevents the spatial memory deficits and the redox-dependent RyR2 decrease displayed by an Alzheimer’s disease rat model J More, N Galusso, P Veloso, L Montecinos, JP Finkelstein, G Sanchez, ... Frontiers in aging neuroscience 10, 399, 2018 | 54 | 2018 |
Calcium release mediated by redox-sensitive RyR2 channels has a central role in hippocampal structural plasticity and spatial memory JY More, BA Bruna, PE Lobos, JL Galaz, PL Figueroa, S Namias, ... Antioxidants & Redox Signaling 29 (12), 1125-1146, 2018 | 47 | 2018 |
The calcium–iron connection in ferroptosis-mediated neuronal death S Gleitze, A Paula-Lima, MT Núñez, C Hidalgo Free Radical Biology and Medicine 175, 28-41, 2021 | 46 | 2021 |
RyR2-Mediated Ca2+ Release and Mitochondrial ROS Generation Partake in the Synaptic Dysfunction Caused by Amyloid β Peptide Oligomers CD SanMartín, P Veloso, T Adasme, P Lobos, B Bruna, J Galaz, A García, ... Frontiers in Molecular Neuroscience 10, 115, 2017 | 44 | 2017 |
Ryanodine receptor-mediated Ca2+ release underlies iron-induced mitochondrial fission and stimulates mitochondrial Ca2+ uptake in primary hippocampal … CD SanMartín, AC Paula-Lima, A García, P Barattini, S Hartel, MT Núñez, ... Frontiers in molecular neuroscience 7, 13, 2014 | 43 | 2014 |