| Paracrine roles of cellular senescence in promoting tumourigenesis JM Gonzalez-Meljem, JR Apps, HC Fraser, JP Martinez-Barbera British journal of cancer 118 (10), 1283-1288, 2018 | 164 | 2018 |
| Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK … JR Apps, G Carreno, JM Gonzalez-Meljem, S Haston, R Guiho, ... Acta neuropathologica 135, 757-777, 2018 | 118 | 2018 |
| Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma JM Gonzalez-Meljem, S Haston, G Carreno, JR Apps, S Pozzi, C Stache, ... Nature communications 8 (1), 1819, 2017 | 100 | 2017 |
| MAPK pathway control of stem cell proliferation and differentiation in the embryonic pituitary provides insights into the pathogenesis of papillary craniopharyngioma S Haston, S Pozzi, G Carreno, S Manshaei, L Panousopoulos, ... Development 144 (12), 2141-2152, 2017 | 87 | 2017 |
| Molecular analyses reveal inflammatory mediators in the solid component and cyst fluid of human adamantinomatous craniopharyngioma AM Donson, J Apps, AM Griesinger, V Amani, DA Witt, RCE Anderson, ... Journal of Neuropathology & Experimental Neurology 76 (9), 779-788, 2017 | 65 | 2017 |
| SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer L Tordella, S Khan, A Hohmeyer, A Banito, S Klotz, S Raguz, N Martin, ... Genes & development 30 (19), 2187-2198, 2016 | 60 | 2016 |
| Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors G Carreno, JR Apps, EJ Lodge, L Panousopoulos, S Haston, ... Development 144 (18), 3289-3302, 2017 | 53 | 2017 |
| The burden of disease in Mexican older adults: premature mortality challenging a limited-resource health system L Parra-Rodríguez, JM González-Meljem, H Gómez-Dantés, ... Journal of aging and health 32 (7-8), 543-553, 2020 | 30 | 2020 |
| Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer S Haston, E Gonzalez-Gualda, S Morsli, J Ge, V Reen, A Calderwood, ... Cancer Cell 41 (7), 1242-1260. e6, 2023 | 29 | 2023 |
| SHH pathway inhibition is protumourigenic in adamantinomatous craniopharyngioma G Carreno, JKR Boult, J Apps, JM Gonzalez-Meljem, S Haston, R Guiho, ... Endocrine-related cancer 26 (3), 355-366, 2019 | 26 | 2019 |
| Stem cells and their role in pituitary tumorigenesis G Carreno, JM Gonzalez-Meljem, S Haston, JP Martinez-Barbera Molecular and Cellular Endocrinology 445, 27-34, 2017 | 26 | 2017 |
| CTNNB1 mutations are clonal in adamantinomatous craniopharyngioma JR Apps, C Stache, JM Gonzalez‐Meljem, A Gutteridge, J Chalker, ... Neuropathology and applied neurobiology 46 (5), 510, 2020 | 23 | 2020 |
| Senescence drives non-cell autonomous tumorigenesis in the pituitary gland JM Gonzalez-Meljem, JP Martinez-Barbera Molecular & cellular oncology 5 (3), e1435180, 2018 | 16 | 2018 |
| Adamantinomatous craniopharyngioma as a model to understand paracrine and senescence-induced tumourigenesis JM Gonzalez-Meljem, JP Martinez-Barbera Cellular and Molecular Life Sciences 78 (10), 4521-4544, 2021 | 14 | 2021 |
| Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma. Nat Commun 8: 1819 JM Gonzalez-Meljem, S Haston, G Carreno, JR Apps, S Pozzi, C Stache, ... | 7 | 2017 |
| Novel Hybrid Inulin–Soy Protein Nanoparticles Simultaneously Loaded with (-)-Epicatechin and Quercetin and Their In Vitro Evaluation JC Ayala-Fuentes, M Soleimani, JJ Magaña, JM Gonzalez-Meljem, ... Nanomaterials 13 (10), 1615, 2023 | 3 | 2023 |
| Applications of CRISPR-cas in ageing research S Haston, S Pozzi, JM Gonzalez-Meljem Clinical Genetics and Genomics of Aging, 213-230, 2020 | 3 | 2020 |
| Unraveling the complexity of the senescence-associated secretory phenotype in adamantinomatous craniopharyngioma using multimodal machine learning analysis EW Prince, JR Apps, J Jeang, K Chee, S Medlin, EM Jackson, R Dudley, ... Neuro-oncology, noae015, 2024 | 1 | 2024 |
| MAPK pathway activation in the embryonic pituitary results in stem cell compartment expansion, differentiation defects and provides insights into the pathogenesis of papillary … S Haston, S Pozzi, G Carreno, S Manshaei, L Panousopoulos, ... Development 2, dev. 150490, 2017 | 1 | 2017 |
| Expression analysis of adamantinomatous craniopharyngioma suggests two subtypes associated with CTNNB1 mutational frequency and highlights potential … JR Apps, N Jani, G Carreno, JM Gonzalez-Meljem, K Tossell, TJ Stone, ... Cancer Research 76 (14_Supplement), 1804-1804, 2016 | 1 | 2016 |
Juan Pedro Martinez-BarberaUCL GOS INSTITUTE OF CHILD HEALTH, DEVELOPMENTAL BIOLOGY AND CANCER, 30 GUILFORD STREET, WC1N 1EH, LONDON, UKVerified email at ucl.ac.uk
