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Brett Colson
Brett Colson
Associate Professor, University of Arizona
Dirección de correo verificada de arizona.edu
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Differential roles of regulatory light chain and myosin binding protein‐C phosphorylations in the modulation of cardiac force development
BA Colson, MR Locher, T Bekyarova, JR Patel, DP Fitzsimons, TC Irving, ...
The Journal of physiology 588 (6), 981-993, 2010
1962010
Protein kinase A–mediated phosphorylation of cMyBP-C increases proximity of myosin heads to actin in resting myocardium
BA Colson, T Bekyarova, MR Locher, DP Fitzsimons, TC Irving, RL Moss
Circulation research 103 (3), 244-251, 2008
1352008
Radial displacement of myosin cross-bridges in mouse myocardium due to ablation of myosin binding protein-C
BA Colson, T Bekyarova, DP Fitzsimons, TC Irving, RL Moss
Journal of molecular biology 367 (1), 36-41, 2007
862007
Myosin binding protein-C phosphorylation is the principal mediator of protein kinase A effects on thick filament structure in myocardium
BA Colson, JR Patel, PP Chen, T Bekyarova, MI Abdalla, CW Tong, ...
Journal of molecular and cellular cardiology 53 (5), 609-616, 2012
812012
Estradiol modulates myosin regulatory light chain phosphorylation and contractility in skeletal muscle of female mice
S Lai, BC Collins, BA Colson, G Kararigas, DA Lowe
American Journal of Physiology-Endocrinology and Metabolism 310 (9), E724-E733, 2016
712016
Site-directed spectroscopy of cardiac myosin-binding protein C reveals effects of phosphorylation on protein structural dynamics
BA Colson, AR Thompson, LM Espinoza-Fonseca, DD Thomas
Proceedings of the National Academy of Sciences 113 (12), 3233-3238, 2016
562016
Dysregulated Nox4 ubiquitination contributes to redox imbalance and age-related severity of acute lung injury
S Palumbo, YJ Shin, K Ahmad, AA Desai, H Quijada, M Mohamed, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 312 (3 …, 2017
422017
The myosin super-relaxed state is disrupted by estradiol deficiency
BA Colson, KJ Petersen, BC Collins, DA Lowe, DD Thomas
Biochemical and biophysical research communications 456 (1), 151-155, 2015
332015
Cardiac myosin binding protein-C restricts intrafilament torsional dynamics of actin in a phosphorylation-dependent manner
BA Colson, IN Rybakova, E Prochniewicz, RL Moss, DD Thomas
Proceedings of the National Academy of Sciences 109 (50), 20437-20442, 2012
292012
Age affects myosin relaxation states in skeletal muscle fibers of female but not male mice
LA Phung, SM Karvinen, BA Colson, DD Thomas, DA Lowe
PloS one 13 (9), e0199062, 2018
272018
N-terminal extension in cardiac myosin-binding protein C regulates myofilament binding
TA Bunch, VC Lepak, RS Kanassatega, BA Colson
Journal of molecular and cellular cardiology 125, 140-148, 2018
252018
Structural dynamics of muscle protein phosphorylation
BA Colson, SJ Gruber, DD Thomas
Journal of muscle research and cell motility 33, 419-429, 2012
202012
Human cardiac myosin–binding protein C restricts actin structural dynamics in a cooperative and phosphorylation-sensitive manner
TA Bunch, RS Kanassatega, VC Lepak, BA Colson
Journal of Biological Chemistry 294 (44), 16228-16240, 2019
192019
Effects of pseudophosphorylation mutants on the structural dynamics of smooth muscle myosin regulatory light chain
LM Espinoza-Fonseca, BA Colson, DD Thomas
Molecular bioSystems 10 (10), 2693-2698, 2014
182014
Cardiac myosin-binding protein C interaction with actin is inhibited by compounds identified in a high-throughput fluorescence lifetime screen
TA Bunch, P Guhathakurta, VC Lepak, AR Thompson, RS Kanassatega, ...
Journal of Biological Chemistry 297 (1), 2021
172021
Spectroscopic probes of muscle proteins
DD Thomas, JM Muretta, BA Colson, RN Mello, D Kast
Comprehensive Biophysics, 226-250, 2012
142012
A high-throughput fluorescence lifetime-based assay to detect binding of myosin-binding protein C to F-actin
TA Bunch, VC Lepak, KM Bortz, BA Colson
Journal of General Physiology 153 (3), e202012707, 2021
112021
Human cardiac myosin-binding protein C phosphorylation-and mutation-dependent structural dynamics monitored by time-resolved FRET
RS Kanassatega, TA Bunch, VC Lepak, C Wang, BA Colson
Journal of molecular and cellular cardiology 166, 116-126, 2022
72022
What a drag!: Skeletal myosin binding protein-C affects sarcomeric shortening
BA Colson
Journal of General Physiology 151 (5), 614-618, 2019
52019
Drug discovery for heart failure targeting myosin-binding protein C
TA Bunch, P Guhathakurta, AR Thompson, VC Lepak, AL Carter, ...
Journal of Biological Chemistry 299 (12), 2023
32023
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