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PD Dr. Basant Kumar Thakur
PD Dr. Basant Kumar Thakur
Faculty member and Group leader Cancer exosomes biology
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Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
B Costa-Silva, NM Aiello, AJ Ocean, S Singh, H Zhang, BK Thakur, ...
Nature cell biology 17 (6), 816-826, 2015
27202015
Extracellular vesicles in cancer: cell-to-cell mediators of metastasis
A Becker, BK Thakur, JM Weiss, HS Kim, H Peinado, D Lyden
Cancer cell 30 (6), 836-848, 2016
17842016
Double-stranded DNA in exosomes: a novel biomarker in cancer detection
BK Thakur, H Zhang, A Becker, I Matei, Y Huang, B Costa-Silva, Y Zheng, ...
Cell research 24 (6), 766-769, 2014
17842014
Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer
P Sansone, C Savini, I Kurelac, Q Chang, LB Amato, A Strillacci, ...
Proceedings of the National Academy of Sciences 114 (43), E9066-E9075, 2017
6542017
NAMPT is essential for the G-CSF–induced myeloid differentiation via a NAD+–sirtuin-1–dependent pathway
J Skokowa, D Lan, BK Thakur, F Wang, K Gupta, G Cario, AM Brechlin, ...
Nature medicine 15 (2), 151-158, 2009
2592009
Functional analysis of KSRP interaction with the AU-rich element of interleukin-8 and identification of inflammatory mRNA targets
R Winzen, BK Thakur, O Dittrich-Breiholz, M Shah, N Redich, S Dhamija, ...
Molecular and cellular biology 27 (23), 8388-8400, 2007
1762007
Histone deacetylase inhibitors induce apoptosis in myeloid leukemia by suppressing autophagy
MV Stankov, M El Khatib, B Kumar Thakur, K Heitmann, ...
Leukemia 28 (3), 577-588, 2014
1302014
Cell of origin in AML: susceptibility to MN1-induced transformation is regulated by the MEIS1/AbdB-like HOX protein complex
M Heuser, H Yun, T Berg, E Yung, B Argiropoulos, F Kuchenbauer, ...
Cancer cell 20 (1), 39-52, 2011
1172011
Glioma: molecular signature and crossroads with tumor microenvironment
L Barthel, M Hadamitzky, P Dammann, M Schedlowski, U Sure, ...
Cancer and Metastasis Reviews, 1-23, 2022
1132022
NAMPT signaling is critical for the proangiogenic activity of tumor‐associated neutrophils
E Pylaeva, MD Harati, I Spyra, S Bordbari, S Strachan, BK Thakur, ...
International journal of cancer 144 (1), 136-149, 2019
832019
MeCP2 Rett mutations affect large scale chromatin organization
N Agarwal, A Becker, KL Jost, S Haase, BK Thakur, A Brero, T Hardt, ...
Human molecular genetics 20 (21), 4187-4195, 2011
802011
DNA in extracellular vesicles: From evolution to its current application in health and disease
J Ghanam, VK Chetty, L Barthel, D Reinhardt, PF Hoyer, BK Thakur
Cell & Bioscience 12 (1), 37, 2022
762022
Involvement of p53 in the cytotoxic activity of the NAMPT inhibitor FK866 in myeloid leukemic cells
BK Thakur, T Dittrich, P Chandra, A Becker, W Kuehnau, JH Klusmann, ...
International journal of cancer 132 (4), 766-774, 2013
662013
Interleukin-1 activates synthesis of interleukin-6 by interfering with a KH-type splicing regulatory protein (KSRP)-dependent translational silencing mechanism
S Dhamija, N Kuehne, R Winzen, A Doerrie, O Dittrich-Breiholz, ...
Journal of Biological Chemistry 286 (38), 33279-33288, 2011
572011
Inhibition of NAMPT pathway by FK866 activates the function of p53 in HEK293T cells
BK Thakur, T Dittrich, P Chandra, A Becker, Y Lippka, D Selvakumar, ...
Biochemical and biophysical research communications 424 (3), 371-377, 2012
472012
Molecular transport machinery involved in orchestrating luminal acid‐induced duodenal bicarbonate secretion in vivo
AK Singh, Y Liu, B Riederer, R Engelhardt, BK Thakur, M Soleimani, ...
The Journal of physiology 591 (21), 5377-5391, 2013
442013
Inhibition of SIRT1 by HIV-1 viral protein Tat results in activation of p53 pathway
BK Thakur, A Chandra, T Dittrich, K Welte, P Chandra
Biochemical and biophysical research communications 424 (2), 245-250, 2012
442012
Evaluation of dsDNA from extracellular vesicles (EVs) in pediatric AML diagnostics
E Kontopoulou, S Strachan, K Reinhardt, F Kunz, C Walter, B Walkenfort, ...
Annals of Hematology 99, 459-475, 2020
392020
Neutrophil elastase is severely down-regulated in severe congenital neutropenia independent of ELA2 or HAX1 mutations but dependent on LEF-1
J Skokowa, JP Fobiwe, L Dan, BK Thakur, K Welte
Blood, The Journal of the American Society of Hematology 114 (14), 3044-3051, 2009
392009
Single extracellular vesicle analysis performed by imaging flow cytometry and nanoparticle tracking analysis evaluate the accuracy of urinary extracellular vesicle preparation …
M Droste, T Tertel, S Jeruschke, R Dittrich, E Kontopoulou, B Walkenfort, ...
International journal of molecular sciences 22 (22), 12436, 2021
312021
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