Robert B Clarke

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Anthony Howell, Howell A, Howell TProfessor of Medical Oncology, Manchester UniversityDirección de correo verificada de picr.man.ac.uk
Bruno M. SimõesUniversity of ManchesterDirección de correo verificada de ics.manchester.ac.uk
Sacha Howellsenior lecturer, Manchester UniversityDirección de correo verificada de nhs.net
Andrew H SimsUniversity of EdinburghDirección de correo verificada de ed.ac.uk
Hannah HarrisonPost-doctoral Research Associate, University of ManchesterDirección de correo verificada de manchester.ac.uk
Evans DG*, Evans G*University of ManchesterDirección de correo verificada de mft.nhs.uk
Rachel EyreUniversity of ManchesterDirección de correo verificada de ics.manchester.ac.uk
Jos JonkersProfessor at Leiden University and group leader at Netherlands Cancer Institute, Oncode InstituteDirección de correo verificada de nki.nl
Angélica Santiago GómezUniversity of ManchesterDirección de correo verificada de manchester.ac.uk
Denis AlferezInstitute of Cancer Research, University of Manchester, UKDirección de correo verificada de ics.manchester.ac.uk
Michelle HarvieUniversity of ManchesterDirección de correo verificada de manchester.ac.uk
Manuel HidalgoWeill Cornell MedicineDirección de correo verificada de med.cornell.edu
Charles StreuliUniversity of ManchesterDirección de correo verificada de manchester.ac.uk
Ernestina Marianna De FrancescoUniversita' degli Studi di CataniaDirección de correo verificada de unict.it
Ahmet AcarMiddle East Technical UniversityDirección de correo verificada de metu.edu.tr
Martin Baronuniversity of manchesterDirección de correo verificada de manchester.ac.uk
Zuzana Sumbalová KoledováMasaryk University, Faculty of MedicineDirección de correo verificada de med.muni.cz
Chiara FrancavillaDanish Technical University and The University of ManchesterDirección de correo verificada de manchester.ac.uk
M Bentires-AljUniversity of Basel

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Robert B Clarke

Professor of Breast Biology, University of Manchester

Dirección de correo verificada de manchester.ac.uk - Página principal

breast cancer stem cells endocrine resistance Notch signalling patient-derived xenografts


Título Ordenar por citas Ordenar por año Ordenar por título	Citado por Citado por	Año
Patient-derived xenograft models: an emerging platform for translational cancer research M Hidalgo, F Amant, AV Biankin, E Budinská, AT Byrne, C Caldas, ... Cancer discovery 4 (9), 998-1013, 2014	1737	2014
Dissociation between steroid receptor expression and cell proliferation in the human breast RB Clarke, A Howell, CS Potten, E Anderson Cancer research 57 (22), 4987-4991, 1997	848	1997
Aberrant activation of notch signaling in human breast cancer S Stylianou, RB Clarke, K Brennan Cancer research 66 (3), 1517-1525, 2006	722	2006
Interrogating open issues in cancer precision medicine with patient-derived xenografts AT Byrne, DG Alférez, F Amant, D Annibali, J Arribas, AV Biankin, A Bruna, ... Nature Reviews Cancer 17 (4), 254-268, 2017	695	2017
Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor H Harrison, G Farnie, SJ Howell, RE Rock, S Stylianou, KR Brennan, ... Cancer research 70 (2), 709-718, 2010	670	2010
Identification of a putative intestinal stem cell and early lineage marker; musashi-1 CS Potten, C Booth, GL Tudor, D Booth, G Brady, P Hurley, G Ashton, ... Differentiation 71 (1), 28-41, 2003	601	2003
Risk determination and prevention of breast cancer A Howell, AS Anderson, RB Clarke, SW Duffy, DG Evans, ... Breast Cancer Research 16, 1-19, 2014	527	2014
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer SA Eccles, EO Aboagye, S Ali, AS Anderson, J Armes, F Berditchevski, ... Breast Cancer Research 15, 1-37, 2013	524	2013
Mammary stem cells and breast cancer—role of Notch signalling G Farnie, RB Clarke Stem cell reviews 3, 169-175, 2007	475	2007
A detailed mammosphere assay protocol for the quantification of breast stem cell activity FL Shaw, H Harrison, K Spence, MP Ablett, BM Simões, G Farnie, ... Journal of mammary gland biology and neoplasia 17, 111-117, 2012	449	2012
Novel cell culture technique for primary ductal carcinoma in situ: role of Notch and epidermal growth factor receptor signaling pathways G Farnie, RB Clarke, K Spence, N Pinnock, K Brennan, NG Anderson, ... Journal of the National Cancer Institute 99 (8), 616-627, 2007	429	2007
A putative human breast stem cell population is enriched for steroid receptor-positive cells RB Clarke, K Spence, E Anderson, A Howell, H Okano, CS Potten Developmental biology 277 (2), 443-456, 2005	411	2005
Estrogen receptor-positive proliferating cells in the normal and precancerous breast BS Shoker, C Jarvis, RB Clarke, E Anderson, J Hewlett, MPA Davies, ... The American journal of pathology 155 (6), 1811-1815, 1999	359	1999
Recent advances reveal IL-8 signaling as a potential key to targeting breast cancer stem cells JK Singh, BM Simões, SJ Howell, G Farnie, RB Clarke Breast Cancer Research 15, 1-9, 2013	293	2013
Origins of breast cancer subtypes and therapeutic implications AH Sims, A Howell, SJ Howell, RB Clarke Nature Clinical Practice Oncology 4 (9), 516-525, 2007	283	2007
Patient-derived xenograft (PDX) models in basic and translational breast cancer research LE Dobrolecki, SD Airhart, DG Alferez, S Aparicio, F Behbod, ... Cancer and Metastasis Reviews 35, 547-573, 2016	275	2016
Estrogen responsiveness and control of normal human breast proliferation E Anderson, RB Clarke, A Howell Journal of mammary gland biology and neoplasia 3, 23-35, 1998	255	1998
The proliferation of normal human breast tissue implanted into athymic nude mice is stimulated by estrogen but not progesterone IJ Laidlaw, RB Clarke, A Howell, AW Owen, CS Potten, E Anderson Endocrinology 136 (1), 164-171, 1995	254	1995
Targeting CXCR1/2 significantly reduces breast cancer stem cell activity and increases the efficacy of inhibiting HER2 via HER2-dependent and-independent mechanisms JK Singh, G Farnie, NJ Bundred, BM Simões, A Shergill, G Landberg, ... Clinical cancer research 19 (3), 643-656, 2013	245	2013
The centrosomal kinase Nek2 displays elevated levels of protein expression in human breast cancer DG Hayward, RB Clarke, AJ Faragher, MR Pillai, IM Hagan, AM Fry Cancer research 64 (20), 7370-7376, 2004	233	2004

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