The role of protein loops and linkers in conformational dynamics and allostery E Papaleo, G Saladino, M Lambrughi, K Lindorff-Larsen, FL Gervasio, ... Chemical reviews 116 (11), 6391-6423, 2016 | 360 | 2016 |
DisProt: intrinsic protein disorder annotation in 2020 A Hatos, B Hajdu-Soltész, AM Monzon, N Palopoli, L Álvarez, ... Nucleic acids research 48 (D1), D269-D276, 2020 | 243 | 2020 |
HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα A Di Rita, A Peschiaroli, P D′ Acunzo, D Strobbe, Z Hu, J Gruber, ... Nature communications 9 (1), 3755, 2018 | 191 | 2018 |
DisProt in 2022: improved quality and accessibility of protein intrinsic disorder annotation F Quaglia, B Mészáros, E Salladini, A Hatos, R Pancsa, LB Chemes, ... Nucleic acids research 50 (D1), D480-D487, 2022 | 126 | 2022 |
PyInteraph: a framework for the analysis of interaction networks in structural ensembles of proteins M Tiberti, G Invernizzi, M Lambrughi, Y Inbar, G Schreiber, E Papaleo Journal of chemical information and modeling 54 (5), 1537-1551, 2014 | 107 | 2014 |
Catalytic mechanism of fungal lytic polysaccharide monooxygenases investigated by first-principles calculations L Bertini, R Breglia, M Lambrughi, P Fantucci, L De Gioia, M Borsari, ... Inorganic chemistry 57 (1), 86-97, 2018 | 97 | 2018 |
Absence of neurofibromin induces an oncogenic metabolic switch via mitochondrial ERK-mediated phosphorylation of the chaperone TRAP1 I Masgras, F Ciscato, AM Brunati, E Tibaldi, S Indraccolo, M Curtarello, ... Cell reports 18 (3), 659-672, 2017 | 89 | 2017 |
An optimal distance cutoff for contact-based Protein Structure Networks using side-chain centers of mass J Salamanca Viloria, MF Allega, M Lambrughi, E Papaleo Scientific reports 7 (1), 2838, 2017 | 88 | 2017 |
Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites SG Holdgaard, V Cianfanelli, E Pupo, M Lambrughi, M Lubas, JC Nielsen, ... Nature communications 10 (1), 4176, 2019 | 68 | 2019 |
E2 superfamily of ubiquitin-conjugating enzymes: constitutively active or activated through phosphorylation in the catalytic cleft I Valimberti, M Tiberti, M Lambrughi, B Sarcevic, E Papaleo Scientific reports 5 (1), 14849, 2015 | 55 | 2015 |
Alterations of the interactome of Bcl-2 proteins in breast cancer at the transcriptional, mutational and structural level SM Kønig, V Rissler, T Terkelsen, M Lambrughi, E Papaleo PLoS computational biology 15 (12), e1007485, 2019 | 54 | 2019 |
DNA-binding protects p53 from interactions with cofactors involved in transcription-independent functions M Lambrughi, L De Gioia, FL Gervasio, K Lindorff-Larsen, R Nussinov, ... Nucleic Acids Research 44 (19), 9096-9109, 2016 | 44 | 2016 |
Communication routes in ARID domains between distal residues in helix 5 and the DNA-binding loops G Invernizzi, M Tiberti, M Lambrughi, K Lindorff-Larsen, E Papaleo PLoS Computational Biology 10 (9), e1003744, 2014 | 44 | 2014 |
A phosphorylation-motif for tuneable helix stabilisation in intrinsically disordered proteins–Lessons from the sodium proton exchanger 1 (NHE1) R Hendus-Altenburger, M Lambrughi, T Terkelsen, SF Pedersen, ... Cellular Signalling 37, 40-51, 2017 | 38 | 2017 |
The mutational landscape of the oncogenic MZF1 SCAN domain in cancer M Nygaard, T Terkelsen, A Vidas Olsen, V Sora, J Salamanca Viloria, ... Frontiers in Molecular Biosciences 3, 78, 2016 | 35 | 2016 |
Bi-allelic mutations in MYL1 cause a severe congenital myopathy G Ravenscroft, IT Zaharieva, CA Bortolotti, M Lambrughi, M Pignataro, ... Human molecular genetics 27 (24), 4263-4272, 2018 | 31 | 2018 |
Intramolecular interactions stabilizing compact conformations of the intrinsically disordered kinase-inhibitor domain of Sic1: a molecular dynamics investigation M Lambrughi, E Papaleo, L Testa, S Brocca, L De Gioia, R Grandori Frontiers in Physiology 3, 32365, 2012 | 31 | 2012 |
The conformational and mutational landscape of the ubiquitin-like marker for autophagosome formation in cancer BA Fas, E Maiani, V Sora, M Kumar, M Mashkoor, M Lambrughi, M Tiberti, ... Autophagy 17 (10), 2818-2841, 2021 | 24 | 2021 |
Structure and dynamics in the ATG8 family from experimental to computational techniques V Sora, M Kumar, E Maiani, M Lambrughi, M Tiberti, E Papaleo Frontiers in Cell and Developmental Biology 8, 420, 2020 | 24 | 2020 |
A comparative study of Whi5 and retinoblastoma proteins: from sequence and structure analysis to intracellular networks MM Hasan, S Brocca, E Sacco, M Spinelli, E Papaleo, M Lambrughi, ... Frontiers in physiology 4, 57552, 2014 | 24 | 2014 |