| Targeting the αv integrin/TGF-β axis improves natural killer cell function against glioblastoma stem cells H Shaim, M Shanley, R Basar, M Daher, J Gumin, DB Zamler, N Uprety, ... The Journal of Clinical Investigation 131 (14), 2021 | 149 | 2021 |
| Immune biology of glioma-associated macrophages and microglia: functional and therapeutic implications J Wei, P Chen, P Gupta, M Ott, D Zamler, C Kassab, KP Bhat, MA Curran, ... Neuro-oncology 22 (2), 180-194, 2020 | 148 | 2020 |
| CXCR4 increases in-vivo glioma perivascular invasion, and reduces radiation induced apoptosis: A genetic knockdown study VN Yadav, D Zamler, GJ Baker, P Kadiyala, A Erdreich-Epstein, ... Oncotarget 7 (50), 83701, 2016 | 87 | 2016 |
| Anti–PD-1 induces M1 polarization in the glioma microenvironment and exerts therapeutic efficacy in the absence of CD8 cytotoxic T cells G Rao, K Latha, M Ott, A Sabbagh, A Marisetty, X Ling, D Zamler, ... Clinical Cancer Research 26 (17), 4699-4712, 2020 | 78 | 2020 |
| Characterizing and targeting PDGFRA alterations in pediatric high-grade glioma C Koschmann, D Zamler, A MacKay, D Robinson, YM Wu, R Doherty, ... Oncotarget 7 (40), 65696, 2016 | 65 | 2016 |
| Mature myelin maintenance requires Qki to coactivate PPARβ-RXRα–mediated lipid metabolism X Zhou, C He, J Ren, C Dai, SR Stevens, Q Wang, D Zamler, T Shingu, ... The Journal of clinical investigation 130 (5), 2220-2236, 2020 | 55 | 2020 |
| Survival and proliferation of neural progenitor–derived glioblastomas under hypoxic stress is controlled by a Cxcl12/Cxcr4 autocrine-positive feedback mechanism AA Calinescu, VN Yadav, E Carballo, P Kadiyala, D Tran, DB Zamler, ... Clinical Cancer Research 23 (5), 1250-1262, 2017 | 49 | 2017 |
| Radiation with STAT3 blockade triggers dendritic cell–T cell interactions in the glioma microenvironment and therapeutic efficacy M Ott, C Kassab, A Marisetty, Y Hashimoto, J Wei, D Zamler, JS Leu, ... Clinical Cancer Research 26 (18), 4983-4994, 2020 | 48 | 2020 |
| Fyn tyrosine kinase, a downstream target of receptor tyrosine kinases, modulates antiglioma immune responses A Comba, PJ Dunn, AE Argento, P Kadiyala, M Ventosa, P Patel, ... Neuro-oncology 22 (6), 806-818, 2020 | 41 | 2020 |
| Spatiotemporal analysis of glioma heterogeneity reveals COL1A1 as an actionable target to disrupt tumor progression A Comba, SM Faisal, PJ Dunn, AE Argento, TC Hollon, WN Al-Holou, ... Nature communications 13 (1), 3606, 2022 | 35 | 2022 |
| Natural killer cells require monocytic Gr-1+/CD11b+ myeloid cells to eradicate orthotopically engrafted glioma cells GJ Baker, P Chockley, D Zamler, MG Castro, PR Lowenstein Oncoimmunology 5 (6), e1163461, 2016 | 34 | 2016 |
| Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration Y Zhou, YB Medik, B Patel, DB Zamler, S Chen, T Chapman, S Schneider, ... Journal of Experimental Medicine 220 (2), e20221333, 2022 | 25 | 2022 |
| Multi-focal sequencing of a diffuse intrinsic pontine glioma establishes PTEN loss as an early event C Koschmann, Z Farooqui, K Kasaian, X Cao, D Zamler, S Stallard, ... NPJ Precision Oncology 1 (1), 32, 2017 | 20 | 2017 |
| Assessing the role of STAT3 in DC differentiation and autologous DC immunotherapy in mouse models of GBM H Assi, J Espinosa, S Suprise, M Sofroniew, R Doherty, D Zamler, ... PLoS One 9 (5), e96318, 2014 | 19 | 2014 |
| A novel miR1983-TLR7-IFNβ circuit licenses NK cells to kill glioma cells, and is under the control of galectin-1 D Shah, A Comba, SM Faisal, P Kadiyala, GJ Baker, MS Alghamri, ... Oncoimmunology 10 (1), 1939601, 2021 | 16 | 2021 |
| Reversibility of glioma stem cells’ phenotypes explains their complex in vitro and in vivo behavior: discovery of a novel neurosphere-specific enzyme, cGMP-dependent protein … TJ Wilson, DB Zamler, R Doherty, MG Castro, PR Lowenstein Oncotarget 7 (39), 63020, 2016 | 14 | 2016 |
| Immune landscape of a genetically engineered murine model of glioma compared with human glioma DB Zamler, T Shingu, LM Kahn, K Huntoon, C Kassab, M Ott, K Tomczak, ... JCI insight 7 (12), 2022 | 11 | 2022 |
| Combined cytotoxic and immune-stimulatory gene therapy for primary adult high-grade glioma: a phase 1, first-in-human trial Y Umemura, D Orringer, L Junck, ML Varela, MEJ West, SM Faisal, ... The Lancet Oncology 24 (9), 1042-1052, 2023 | 9 | 2023 |
| Genetic and immune profiling for potential therapeutic targets in adult human craniopharyngioma C Kassab, D Zamler, C Kamiya-Matsuoka, Z Gatalica, J Xiu, D Spetzler, ... Clinical oncology and research 2 (3), 2, 2019 | 9 | 2019 |
| Molecular ablation of tumor blood vessels inhibits therapeutic effects of radiation and bevacizumab VN Yadav, D Altshuler, P Kadiyala, D Zamler, A Comba, H Appelman, ... Neuro-oncology 20 (10), 1356-1367, 2018 | 8 | 2018 |
