| VEGF-induced vascular permeability is mediated by FAK XL Chen, JO Nam, C Jean, C Lawson, CT Walsh, E Goka, ST Lim, ... Developmental cell 22 (1), 146-157, 2012 | 386 | 2012 |
| Inhibition of endothelial FAK activity prevents tumor metastasis by enhancing barrier function C Jean, XL Chen, JO Nam, I Tancioni, S Uryu, C Lawson, KK Ward, ... Journal of Cell Biology 204 (2), 247-263, 2014 | 179 | 2014 |
| PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments I Tanjoni, C Walsh, S Uryu, A Tomar, JO Nam, A Mielgo, ST Lim, C Liang, ... Cancer biology & therapy 9 (10), 764-777, 2010 | 175 | 2010 |
| Importance of snake venom metalloproteinases in cell biology: effects on platelets, inflammatory and endothelial cells AM Moura-da-Silva, D Butera, I Tanjoni Current pharmaceutical design 13 (28), 2893-2905, 2007 | 153 | 2007 |
| Oral delivery of PND-1186 FAK inhibitor decreases tumor growth and spontaneous breast to lung metastasis in pre-clinical models C Walsh, I Tanjoni, S Uryu, A Tomar, JO Nam, H Luo, A Phillips, N Patel, ... Cancer biology & therapy 9 (10), 778-790, 2010 | 152 | 2010 |
| Nuclear-localized focal adhesion kinase regulates inflammatory VCAM-1 expression ST Lim, NLG Miller, XL Chen, I Tancioni, CT Walsh, C Lawson, S Uryu, ... Journal of Cell Biology 197 (7), 907-919, 2012 | 130 | 2012 |
| Inhibition of focal adhesion kinase (FAK) activity prevents anchorage-independent ovarian carcinoma cell growth and tumor progression KK Ward, I Tancioni, C Lawson, NLG Miller, C Jean, XL Chen, S Uryu, ... Clinical & experimental metastasis 30, 579-594, 2013 | 120 | 2013 |
| Jararhagin, a snake venom metalloproteinase, induces a specialized form of apoptosis (anoikis) selective to endothelial cells I Tanjoni, R Weinlich, MS Della-Casa, PB Clissa, RF Saldanha-Gama, ... Apoptosis 10, 851-861, 2005 | 119 | 2005 |
| FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy CJ Diaz Osterman, D Ozmadenci, EG Kleinschmidt, KN Taylor, AM Barrie, ... Elife 8, e47327, 2019 | 94 | 2019 |
| Collagen binding is a key factor for the hemorrhagic activity of snake venom metalloproteinases AM Moura-da-Silva, OHP Ramos, C Baldo, S Niland, U Hansen, ... Biochimie 90 (3), 484-492, 2008 | 81 | 2008 |
| BnP1, a novel PI metalloproteinase from Bothrops neuwiedi venom: biological effects benchmarking relatively to jararhagin, a P-III SVMP C Baldo, I Tanjoni, IR León, IFC Batista, MS Della-Casa, PB Clissa, ... Toxicon 51 (1), 54-65, 2008 | 75 | 2008 |
| p190RhoGEF (Rgnef) promotes colon carcinoma tumor progression via interaction with focal adhesion kinase HG Yu, JO Nam, NLG Miller, I Tanjoni, C Walsh, L Shi, L Kim, XL Chen, ... Cancer research 71 (2), 360-370, 2011 | 62 | 2011 |
| FAK inhibition disrupts a β5 integrin signaling axis controlling anchorage-independent ovarian carcinoma growth I Tancioni, S Uryu, FJ Sulzmaier, NR Shah, C Lawson, NLG Miller, C Jean, ... Molecular cancer therapeutics 13 (8), 2050-2061, 2014 | 61 | 2014 |
| Characterisation of local inflammatory response induced by Thalassophryne nattereri fish venom in a mouse model of tissue injury C Lima, PB Clissa, AA Piran-Soares, I Tanjoni, AM Moura-da-Silva, ... Toxicon 42 (5), 499-507, 2003 | 61 | 2003 |
| Snake venom metalloproteinases: structure/function relationships studies using monoclonal antibodies I Tanjoni, D Butera, L Bento, MS Della-Casa, R Marques-Porto, ... Toxicon 42 (7), 801-808, 2003 | 58 | 2003 |
| Different regions of the class P-III snake venom metalloproteinase jararhagin are involved in binding to α2β1 integrin and collagen I Tanjoni, K Evangelista, MS Della-Casa, D Butera, GS Magalhaes, ... Toxicon 55 (6), 1093-1099, 2010 | 57 | 2010 |
| FAK activity protects nucleostemin in facilitating breast cancer spheroid and tumor growth I Tancioni, NLG Miller, S Uryu, C Lawson, C Jean, XL Chen, ... Breast Cancer Research 17, 1-17, 2015 | 55 | 2015 |
| Analyses of merlin/NF2 connection to FAK inhibitor responsiveness in serous ovarian cancer NR Shah, I Tancioni, KK Ward, C Lawson, XL Chen, C Jean, FJ Sulzmaier, ... Gynecologic oncology 134 (1), 104-111, 2014 | 55 | 2014 |
| Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer JR Delaney, CB Patel, KMC Willis, M Haghighiabyaneh, J Axelrod, ... Nature communications 8 (1), 14423, 2017 | 48 | 2017 |
| Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors JR Delaney, CB Patel, J Bapat, CM Jones, M Ramos-Zapatero, KK Ortell, ... PLoS genetics 16 (1), e1008558, 2020 | 43 | 2020 |
D. StupackUCSD Moores Cancer CenterVerified email at ucsd.edu
