Lena Ruiz-Azuara
Lena Ruiz-Azuara
Profesora de Química UNAM
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Copper compounds in cancer chemotherapy
L Ruiz-Azuara, M E Bravo-Gomez
Current medicinal chemistry 17 (31), 3606-3615, 2010
Antiproliferative activity and QSAR study of copper (II) mixed chelate [Cu (N–N)(acetylacetonato)] NO3 and [Cu (N–N)(glycinato)] NO3 complexes,(Casiopeínas®)
ME Bravo-Gómez, JC García-Ramos, I Gracia-Mora, L Ruiz-Azuara
Journal of inorganic biochemistry 103 (2), 299-309, 2009
Genotoxicity of the copper antineoplastic coordination complexes casiopeinas®
J Serment-Guerrero, P Cano-Sanchez, E Reyes-Perez, ...
Toxicology in Vitro 25 (7), 1376-1384, 2011
Intercalation processes of copper complexes in DNA
R Galindo-Murillo, JC García-Ramos, L Ruiz-Azuara, TE Cheatham, ...
Nucleic acids research 43 (11), 5364-5376, 2015
Copper compound induces autophagy and apoptosis of glioma cells by reactive oxygen species and JNK activation
C Trejo-Solís, D Jimenez-Farfan, S Rodriguez-Enriquez, ...
BMC cancer 12, 1-15, 2012
Casiopeina III-ia induces apoptosis in HCT-15 cells in vitro through caspase-dependent mechanisms and has antitumor effect in vivo
F Carvallo-Chaigneau, C Trejo-Solís, C Gómez-Ruiz, ...
Biometals 21, 17-28, 2008
Induction of oxidative damage by copper-based antineoplastic drugs (Casiopeínas®)
R Alemón-Medina, M Breña-Valle, JL Muñoz-Sánchez, MI Gracia-Mora, ...
Cancer chemotherapy and pharmacology 60, 219-228, 2007
Control of cellular proliferation by modulation of oxidative phosphorylation in human and rodent fast-growing tumor cells
S Rodríguez-Enríquez, PA Vital-González, FL Flores-Rodríguez, ...
Toxicology and applied pharmacology 215 (2), 208-217, 2006
Casiopeína IIgly-induced oxidative stress and mitochondrial dysfunction in human lung cancer A549 and H157 cells
R Kachadourian, HM Brechbuhl, L Ruiz-Azuara, I Gracia-Mora, BJ Day
Toxicology 268 (3), 176-183, 2010
Metal-based drug-DNA interactions
JC García-Ramos, R Galindo-Murillo, F Cortés-Guzmán, L Ruiz-Azuara
Journal of the Mexican Chemical Society 57 (3), 245-259, 2013
New achievements on biological aspects of copper complexes Casiopeínas®: Interaction with DNA and proteins and anti-Trypanosoma cruzi activity
L Becco, A Rodríguez, ME Bravo, MJ Prieto, L Ruiz-Azuara, B Garat, ...
Journal of inorganic biochemistry 109, 49-56, 2012
Casiopeinas IIgly and IIIia induce apoptosis in medulloblastoma cells
C Mejia, L Ruiz-Azuara
Pathology & Oncology Research 14, 467-472, 2008
Genotoxic assessment of the copper chelated compounds Casiopeinas: Clues about their mechanisms of action
J Serment-Guerrero, ME Bravo-Gomez, E Lara-Rivera, L Ruiz-Azuara
Journal of inorganic biochemistry 166, 68-75, 2017
Molecular recognition between DNA and a copper-based anticancer complex
R Galindo-Murillo, L Ruíz-Azuara, R Moreno-Esparza, F Cortés-Guzmán
Physical Chemistry Chemical Physics 14 (44), 15539-15546, 2012
Casiopeína IIgly induced cytotoxicity to HeLa cells depletes the levels of reduced glutathione and is prevented by dimethyl sulfoxide
R Alemón-Medina, JL Muñoz-Sánchez, L Ruiz-Azuara, I Gracia-Mora
Toxicology in Vitro 22 (3), 710-715, 2008
Copper (II) mixed chelate compounds induce apoptosis through reactive oxygen species in neuroblastoma cell line CHP-212
AG Gutiérrez, A Vázquez-Aguirre, JC García-Ramos, M Flores-Alamo, ...
Journal of inorganic biochemistry 126, 17-25, 2013
π-Stacking between Casiopeinas® and DNA bases
R Galindo-Murillo, J Hernandez-Lima, M González-Rendón, ...
Physical Chemistry Chemical Physics 13 (32), 14510-14515, 2011
The mitochondrial apoptotic pathway is induced by Cu(II) antineoplastic compounds (Casiopeínas®) in SK-N-SH neuroblastoma cells after short exposure times
JC García-Ramos, AG Gutiérrez, A Vázquez-Aguirre, Y Toledano-Magaña, ...
Biometals 30, 43-58, 2017
Transformation of thiophene, benzothiophene and dibenzothiophene over Pt/HMFI, Pt/HMOR and Pt/HFAU: Effect of reactant molecular dimensions and zeolite pore diameter over …
R Contreras, R Cuevas-García, J Ramírez, L Ruiz-Azuara, ...
Catalysis today 130 (2-4), 320-326, 2008
Whole genome gene expression analysis reveals casiopeina-induced apoptosis pathways
AI Valencia-Cruz, LI Uribe-Figueroa, R Galindo-Murillo, K Baca-Lopez, ...
PloS one 8 (1), e54664, 2013
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