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Hidde Ploegh
Hidde Ploegh
Senior Investigator, Program in Cellular and Molecular Medicine, Boston Children's Hospital
Dirección de correo verificada de childrens.harvard.edu
Título
Citado por
Citado por
Año
Molecular cell biology
HF Lodish
Macmillan, 2008
134392008
Genome-scale CRISPR-mediated control of gene repression and activation
LA Gilbert, MA Horlbeck, B Adamson, JE Villalta, Y Chen, EH Whitehead, ...
Cell 159 (3), 647-661, 2014
28882014
CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance
JH Niess, S Brand, X Gu, L Landsman, S Jung, BA McCormick, JM Vyas, ...
Science 307 (5707), 254-258, 2005
19652005
Sec6l-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction
EJHJ Wiertz, D Tortorella, M Bogyo, J Yu, W Mothes, TR Jones, ...
Nature 384 (6608), 432-438, 1996
14421996
The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol
EJHJ Wiertz, TR Jones, L Sun, M Bogyo, HJ Geuze, HL Ploegh
Cell 84 (5), 769-779, 1996
13871996
Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining
T Maruyama, SK Dougan, MC Truttmann, AM Bilate, JR Ingram, ...
Nature biotechnology 33 (5), 538-542, 2015
13532015
Empty MHC class I molecules come out in the cold
HG Ljunggren, NJ Stam, C Öhlén, JJ Neefjes, P Höglund, MT Heemels, ...
Nature 346 (6283), 476-480, 1990
11511990
Herpes simplex virus turns off the TAP to evade host immunity
A Hill, P Jugovic, lan York, G Russ, J Bennink, J Yewdell, H Ploegh, ...
Nature 375 (6530), 411-415, 1995
10841995
Viral subversion of the immune system
D Tortorella, BE Gewurz, MH Furman, DJ Schust, HL Ploegh
Annual review of immunology 18 (1), 861-926, 2000
10282000
Viral strategies of immune evasion
HL Ploegh
Science 280 (5361), 248-253, 1998
10151998
The known unknowns of antigen processing and presentation
JM Vyas, AG Van der Veen, HL Ploegh
Nature Reviews Immunology 8 (8), 607-618, 2008
9352008
TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4− 8+ T cells
L Van Kaer, PG Ashton-Rickardt, HL Ploegh, S Tonegawa
Cell 71 (7), 1205-1214, 1992
8791992
A membrane protein required for dislocation of misfolded proteins from the ER
BN Lilley, HL Ploegh
Nature 429 (6994), 834-840, 2004
8632004
Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus
T Nakagawa, W Roth, P Wong, A Nelson, A Farr, J Deussing, ...
Science 280 (5362), 450-453, 1998
8621998
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
YM Kim, MM Brinkmann, ME Paquet, HL Ploegh
Nature 452 (7184), 234-238, 2008
8462008
Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments
PJ Peters, JJ Neefjes, V Oorschot, HL Ploegh, HJ Geuze
Nature 349 (6311), 669-676, 1991
8251991
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration
SM Lehmann, C Krüger, B Park, K Derkow, K Rosenberger, J Baumgart, ...
Nature neuroscience 15 (6), 827-835, 2012
8162012
Road to ruin: targeting proteins for degradation in the endoplasmic reticulum
MH Smith, HL Ploegh, JS Weissman
Science 334 (6059), 1086-1090, 2011
7732011
Multiple associated proteins regulate proteasome structure and function
DS Leggett, J Hanna, A Borodovsky, B Crosas, M Schmidt, RT Baker, ...
Molecular cell 10 (3), 495-507, 2002
7632002
Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase
RA Gruters, JJ Neefjes, M Tersmette, REY de Goede, A Tulp, ...
Nature 330 (6143), 74-77, 1987
7471987
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