John J. Shacka
John J. Shacka
UAB Dept. Pharmacology & Toxicology
Verified email at - Homepage
Cited by
Cited by
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
Erythropoietin receptor signalling is required for normal brain development
X Yu, JJ Shacka, JB Eells, C Suarez-Quian, RM Przygodzki, ...
Oxford University Press for The Company of Biologists Limited 129 (2), 505-516, 2002
Antioxidants and free radical scavengers for the treatment of stroke, traumatic brain injury and aging
JE Slemmer, JJ Shacka, MI Sweeney, JT Weber
Current medicinal chemistry 15 (4), 404-414, 2008
MHCII is required for α-synuclein-induced activation of microglia, CD4 T cell proliferation, and dopaminergic neurodegeneration
AS Harms, S Cao, AL Rowse, AD Thome, X Li, LR Mangieri, RQ Cron, ...
Journal of Neuroscience 33 (23), 9592-9600, 2013
Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy
Q Yang, H She, M Gearing, E Colla, M Lee, JJ Shacka, Z Mao
Science 323 (5910), 124-127, 2009
Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity
L Qiao, S Hamamichi, KA Caldwell, GA Caldwell, TA Yacoubian, S Wilson, ...
Molecular brain 1, 1-18, 2008
Bafilomycin A1 inhibits chloroquine-induced death of cerebellar granule neurons
JJ Shacka, BJ Klocke, M Shibata, Y Uchiyama, G Datta, RE Schmidt, ...
Molecular pharmacology 69 (4), 1125-1136, 2006
The autophagy-lysosomal degradation pathway: role in neurodegenerative disease and therapy
JJ Shacka, KA Roth, J Zhang
Front Biosci 13, 718-736, 2008
Tristetraprolin down-regulates interleukin-8 and vascular endothelial growth factor in malignant glioma cells
E Suswam, Y Li, X Zhang, GY Gillespie, X Li, JJ Shacka, L Lu, L Zheng, ...
Cancer research 68 (3), 674-682, 2008
Autophagy, bafilomycin and cell death: the “aB-cs” of plecomacrolide-induced neuroprotection
JJ Shacka, BJ Klocke, KA Roth
Autophagy 2 (3), 228-230, 2006
Oxidative stress and autophagy in the regulation of lysosome-dependent neuron death
VN Pivtoraiko, SL Stone, KA Roth, JJ Shacka
Antioxidants & redox signaling 11 (3), 481-496, 2009
Kainic acid induces early and transient autophagic stress in mouse hippocampus
JJ Shacka, J Lu, ZL Xie, Y Uchiyama, KA Roth, J Zhang
Neuroscience letters 414 (1), 57-60, 2007
Cathepsin D deficiency induces persistent neurodegeneration in the absence of Bax-dependent apoptosis
JJ Shacka, BJ Klocke, C Young, M Shibata, JW Olney, Y Uchiyama, ...
Journal of Neuroscience 27 (8), 2081-2090, 2007
Regulation of neuronal cell death and neurodegeneration by members of the Bcl-2 family: therapeutic implications
JJ Shacka, KA Roth
Current Drug Targets-CNS & Neurological Disorders 4 (1), 25-39, 2005
Rotenone inhibits autophagic flux prior to inducing cell death
BJ Mader, VN Pivtoraiko, HM Flippo, BJ Klocke, KA Roth, LR Mangieri, ...
ACS chemical neuroscience 3 (12), 1063-1072, 2012
Two distinct signaling pathways regulate peroxynitrite-induced apoptosis in PC12 cells
JJ Shacka, MA Garner, JD Gonzalez, YZ Ye, TL D'alessandro, AG Estevez
Cell Death & Differentiation 13 (9), 1506-1514, 2006
Lysosome dysfunction triggers Atg7-dependent neural apoptosis
KC Walls, AP Ghosh, AV Franklin, BJ Klocke, M Ballestas, JJ Shacka, ...
Journal of biological chemistry 285 (14), 10497-10507, 2010
Low‐dose bafilomycin attenuates neuronal cell death associated with autophagy‐lysosome pathway dysfunction
VN Pivtoraiko, AJ Harrington, BJ Mader, AM Luker, GA Caldwell, ...
Journal of neurochemistry 114 (4), 1193-1204, 2010
O-GlcNAc regulation of autophagy and α-synuclein homeostasis; implications for Parkinson’s disease
WY Wani, X Ouyang, GA Benavides, M Redmann, SS Cofield, JJ Shacka, ...
Molecular brain 10, 1-14, 2017
HIV-1 and morphine regulation of autophagy in microglia: limited interactions in the context of HIV-1 infection and opioid abuse
N El-Hage, M Rodriguez, SM Dever, RR Masvekar, DA Gewirtz, ...
Journal of virology 89 (2), 1024-1035, 2015
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