| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13258* | 2021 |
| Antioxidants and free radical scavengers for the treatment of stroke, traumatic brain injury and aging JE Slemmer, JJ Shacka, MI Sweeney, JT Weber Current medicinal chemistry 15 (4), 404-414, 2008 | 495 | 2008 |
| Erythropoietin receptor signalling is required for normal brain development X Yu, JJ Shacka, JB Eells, C Suarez-Quian, RM Przygodzki, ... Oxford University Press for The Company of Biologists Limited 129 (2), 505-516, 2002 | 494 | 2002 |
| MHCII is required for α-synuclein-induced activation of microglia, CD4 T cell proliferation, and dopaminergic neurodegeneration AS Harms, S Cao, AL Rowse, AD Thome, X Li, LR Mangieri, RQ Cron, ... Journal of Neuroscience 33 (23), 9592-9600, 2013 | 401 | 2013 |
| Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy Q Yang, H She, M Gearing, E Colla, M Lee, JJ Shacka, Z Mao Science 323 (5910), 124-127, 2009 | 370 | 2009 |
| Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity L Qiao, S Hamamichi, KA Caldwell, GA Caldwell, TA Yacoubian, S Wilson, ... Molecular brain 1, 1-18, 2008 | 276 | 2008 |
| Bafilomycin A1 inhibits chloroquine-induced death of cerebellar granule neurons JJ Shacka, BJ Klocke, M Shibata, Y Uchiyama, G Datta, RE Schmidt, ... Molecular pharmacology 69 (4), 1125-1136, 2006 | 191 | 2006 |
| The autophagy-lysosomal degradation pathway: role in neurodegenerative disease and therapy JJ Shacka, KA Roth, J Zhang Front Biosci 13, 718-736, 2008 | 178 | 2008 |
| Tristetraprolin down-regulates interleukin-8 and vascular endothelial growth factor in malignant glioma cells E Suswam, Y Li, X Zhang, GY Gillespie, X Li, JJ Shacka, L Lu, L Zheng, ... Cancer research 68 (3), 674-682, 2008 | 157 | 2008 |
| Oxidative stress and autophagy in the regulation of lysosome-dependent neuron death VN Pivtoraiko, SL Stone, KA Roth, JJ Shacka Antioxidants & redox signaling 11 (3), 481-496, 2009 | 151 | 2009 |
| Autophagy, bafilomycin and cell death: the “aB-cs” of plecomacrolide-induced neuroprotection JJ Shacka, BJ Klocke, KA Roth Autophagy 2 (3), 228-230, 2006 | 148 | 2006 |
| Kainic acid induces early and transient autophagic stress in mouse hippocampus JJ Shacka, J Lu, ZL Xie, Y Uchiyama, KA Roth, J Zhang Neuroscience letters 414 (1), 57-60, 2007 | 129 | 2007 |
| Cathepsin D deficiency induces persistent neurodegeneration in the absence of Bax-dependent apoptosis JJ Shacka, BJ Klocke, C Young, M Shibata, JW Olney, Y Uchiyama, ... Journal of Neuroscience 27 (8), 2081-2090, 2007 | 121 | 2007 |
| Regulation of neuronal cell death and neurodegeneration by members of the Bcl-2 family: therapeutic implications JJ Shacka, KA Roth Current Drug Targets-CNS & Neurological Disorders 4 (1), 25-39, 2005 | 114 | 2005 |
| Rotenone inhibits autophagic flux prior to inducing cell death BJ Mader, VN Pivtoraiko, HM Flippo, BJ Klocke, KA Roth, LR Mangieri, ... ACS chemical neuroscience 3 (12), 1063-1072, 2012 | 111 | 2012 |
| Two distinct signaling pathways regulate peroxynitrite-induced apoptosis in PC12 cells JJ Shacka, MA Garner, JD Gonzalez, YZ Ye, TL D'alessandro, AG Estevez Cell Death & Differentiation 13 (9), 1506-1514, 2006 | 101 | 2006 |
| Lysosome dysfunction triggers Atg7-dependent neural apoptosis KC Walls, AP Ghosh, AV Franklin, BJ Klocke, M Ballestas, JJ Shacka, ... Journal of Biological Chemistry 285 (14), 10497-10507, 2010 | 99 | 2010 |
| Low‐dose bafilomycin attenuates neuronal cell death associated with autophagy‐lysosome pathway dysfunction VN Pivtoraiko, AJ Harrington, BJ Mader, AM Luker, GA Caldwell, ... Journal of neurochemistry 114 (4), 1193-1204, 2010 | 91 | 2010 |
| O-GlcNAc regulation of autophagy and α-synuclein homeostasis; implications for Parkinson’s disease WY Wani, X Ouyang, GA Benavides, M Redmann, SS Cofield, JJ Shacka, ... Molecular brain 10, 1-14, 2017 | 86 | 2017 |
| HIV-1 and morphine regulation of autophagy in microglia: limited interactions in the context of HIV-1 infection and opioid abuse N El-Hage, M Rodriguez, SM Dever, RR Masvekar, DA Gewirtz, ... Journal of virology 89 (2), 1024-1035, 2015 | 84 | 2015 |
