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Sjoerd Klarenbeek
Sjoerd Klarenbeek
Veterinary pathologist, Royal GD Animal Health
Dirección de correo verificada de gddiergezondheid.nl
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BRCA1 RING function is essential for tumor suppression but dispensable for therapy resistance
R Drost, P Bouwman, S Rottenberg, U Boon, E Schut, S Klarenbeek, ...
Cancer cell 20 (6), 797-809, 2011
3002011
Modeling invasive lobular breast carcinoma by CRISPR/Cas9-mediated somatic genome editing of the mammary gland
S Annunziato, SM Kas, M Nethe, H Yücel, J Del Bravo, C Pritchard, RB Ali, ...
Genes & development 30 (12), 1470-1480, 2016
1662016
BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1
R Drost, KK Dhillon, H Van Der Gulden, I Van Der Heijden, I Brandsma, ...
The Journal of clinical investigation 126 (8), 2903-2918, 2016
1342016
XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data
RJC Kluin, K Kemper, T Kuilman, JR de Ruiter, V Iyer, JV Forment, ...
BMC bioinformatics 19, 1-15, 2018
1242018
Insertional mutagenesis identifies drivers of a novel oncogenic pathway in invasive lobular breast carcinoma
SM Kas, JR De Ruiter, K Schipper, S Annunziato, E Schut, S Klarenbeek, ...
Nature genetics 49 (8), 1219-1230, 2017
922017
Multiple low dose therapy as an effective strategy to treat EGFR inhibitor-resistant NSCLC tumours
JM Fernandes Neto, E Nadal, E Bosdriesz, SN Ooft, L Farre, C McLean, ...
Nature communications 11 (1), 3157, 2020
822020
A preclinical mouse model of invasive lobular breast cancer metastasis
CW Doornebal, S Klarenbeek, TM Braumuller, CN Klijn, M Ciampricotti, ...
Cancer research 73 (1), 353-363, 2013
812013
Loss of p120-catenin induces metastatic progression of breast cancer by inducing anoikis resistance and augmenting growth factor receptor signaling
RCJ Schackmann, S Klarenbeek, EJ Vlug, S Stelloo, M Van Amersfoort, ...
Cancer research 73 (15), 4937-4949, 2013
652013
PTEN loss in E-cadherin-deficient mouse mammary epithelial cells rescues apoptosis and results in development of classical invasive lobular carcinoma
MC Boelens, M Nethe, S Klarenbeek, JR de Ruiter, E Schut, N Bonzanni, ...
Cell reports 16 (8), 2087-2101, 2016
632016
Truncated FGFR2 is a clinically actionable oncogene in multiple cancers
D Zingg, J Bhin, J Yemelyanenko, SM Kas, F Rolfs, C Lutz, JK Lee, ...
Nature 608 (7923), 609-617, 2022
622022
Cross-species comparison of aCGH data from mouse and human BRCA1- and BRCA2-mutated breast cancers
H Holstege, E van Beers, A Velds, X Liu, SA Joosse, S Klarenbeek, ...
BMC cancer 10, 1-16, 2010
492010
Effect of growth-promoting 17β-estradiol, 19-nortestosterone and dexamethasone on circulating levels of nine potential biomarker candidates in veal calves
G Cacciatore, SWF Eisenberg, C Situ, MH Mooney, P Delahaut, ...
Analytica Chimica Acta 637 (1-2), 351-359, 2009
472009
Transcriptomics and transposon mutagenesis identify multiple mechanisms of resistance to the FGFR inhibitor AZD4547
SM Kas, JR De Ruiter, K Schipper, E Schut, L Bombardelli, E Wientjens, ...
Cancer Research 78 (19), 5668-5679, 2018
422018
Genetically engineered mouse models of PI3K signaling in breast cancer
S Klarenbeek, MH van Miltenburg, J Jonkers
Molecular Oncology 7 (2), 146-164, 2013
402013
CD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer
JM Houthuijzen, R De Bruijn, E Van Der Burg, AP Drenth, E Wientjens, ...
Nature Communications 14 (1), 183, 2023
382023
Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L‐dose dependency in HDAC1‐deficient thymic lymphoma
H Vlaming, CM McLean, T Korthout, MF Alemdehy, S Hendriks, C Lancini, ...
The EMBO Journal 38 (14), e101564, 2019
352019
RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells
Z Zhang, X Kong, MA Ligtenberg, SE Van Hal-van Veen, NL Visser, ...
Cell Reports Medicine 3 (6), 2022
312022
Somatic structural rearrangements in genetically engineered mouse mammary tumors
I Varela, C Klijn, PJ Stephens, LJ Mudie, L Stebbings, D Galappaththige, ...
Genome biology 11, 1-12, 2010
282010
Expression of receptors for luteinizing hormone, gastric-inhibitory polypeptide, and vasopressin in normal adrenal glands and cortisol-secreting adrenocortical tumors in dogs
S Galac, VJ Kars, S Klarenbeek, KJ Teerds, JA Mol, HS Kooistra
Domestic animal endocrinology 39 (1), 63-75, 2010
232010
Influence of 17β-oestradiol, nortestosterone and dexamethasone on the adaptive immune response in veal calves
SWF Eisenberg, G Cacciatore, S Klarenbeek, AA Bergwerff, AP Koets
Research in veterinary science 84 (2), 199-205, 2008
202008
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Artículos 1–20