The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis A Roczniak-Ferguson, CS Petit, F Froehlich, S Qian, J Ky, B Angarola, ... Science signaling 5 (228), ra42-ra42, 2012 | 1352 | 2012 |
Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast LMF De Godoy, JV Olsen, J Cox, ML Nielsen, NC Hubner, F Fröhlich, ... Nature 455 (7217), 1251-1254, 2008 | 1088 | 2008 |
Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets F Wilfling, H Wang, JT Haas, N Krahmer, TJ Gould, A Uchida, JX Cheng, ... Developmental cell 24 (4), 384-399, 2013 | 856 | 2013 |
Deep and highly sensitive proteome coverage by LC-MS/MS without prefractionation SS Thakur, T Geiger, B Chatterjee, P Bandilla, F Fröhlich, J Cox, M Mann Molecular & Cellular Proteomics 10 (8), 2011 | 426 | 2011 |
Seipin is required for converting nascent to mature lipid droplets H Wang, M Becuwe, BE Housden, C Chitraju, AJ Porras, MM Graham, ... elife 5, e16582, 2016 | 370 | 2016 |
Rab GTPase function in endosome and lysosome biogenesis L Langemeyer, F Fröhlich, C Ungermann Trends in cell biology 28 (11), 957-970, 2018 | 347 | 2018 |
Global proteome turnover analyses of the yeasts S. cerevisiae and S. pombe R Christiano, N Nagaraj, F Fröhlich, TC Walther Cell reports 9 (5), 1959-1965, 2014 | 300 | 2014 |
QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology V Guarani, EM McNeill, JA Paulo, EL Huttlin, F Fröhlich, SP Gygi, ... Elife 4, e06265, 2015 | 178 | 2015 |
Global analysis of the yeast osmotic stress response by quantitative proteomics B Soufi, CD Kelstrup, G Stoehr, F Fröhlich, TC Walther, JV Olsen Molecular bioSystems 5 (11), 1337-1346, 2009 | 174 | 2009 |
A genome-wide screen for genes affecting eisosomes reveals Nce102 function in sphingolipid signaling F Fröhlich, K Moreira, PS Aguilar, NC Hubner, M Mann, P Walter, ... Journal of Cell Biology 185 (7), 1227-1242, 2009 | 147 | 2009 |
Pkh‐kinases control eisosome assembly and organization TC Walther, PS Aguilar, F Fröhlich, F Chu, K Moreira, AL Burlingame, ... The EMBO journal 26 (24), 4946-4955, 2007 | 141 | 2007 |
Vps39 interacts with Tom40 to establish one of two functionally distinct vacuole-mitochondria contact sites AG Montoro, K Auffarth, C Hoenscher, M Bohnert, T Becker, B Warscheid, ... Developmental cell 45 (5), 621-636. e7, 2018 | 131 | 2018 |
A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking PS Aguilar, F Fröhlich, M Rehman, M Shales, I Ulitsky, A Olivera-Couto, ... Nature structural & molecular biology 17 (7), 901-908, 2010 | 120 | 2010 |
The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1 D Acosta-Alvear, GE Karagöz, F Fröhlich, H Li, TC Walther, P Walter Elife 7, e43036, 2018 | 110 | 2018 |
The GARP complex is required for cellular sphingolipid homeostasis F Fröhlich, C Petit, N Kory, R Christiano, HK Hannibal-Bach, M Graham, ... Elife 4, e08712, 2015 | 104 | 2015 |
Endosome and Golgi‐associated degradation (EGAD) of membrane proteins regulates sphingolipid metabolism O Schmidt, Y Weyer, V Baumann, MA Widerin, S Eising, M Angelova, ... The EMBO Journal 38 (15), e101433, 2019 | 91 | 2019 |
Taming the sphinx: Mechanisms of cellular sphingolipid homeostasis DK Olson, F Fröhlich, RV Farese Jr, TC Walther Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2016 | 83 | 2016 |
Seg1 controls eisosome assembly and shape KE Moreira, S Schuck, B Schrul, F Fröhlich, JB Moseley, TC Walther, ... Journal of Cell Biology 198 (3), 405-420, 2012 | 72 | 2012 |
Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor AH Ponsford, TA Ryan, A Raimondi, E Cocucci, SA Wycislo, F Fröhlich, ... Autophagy 17 (6), 1500-1518, 2021 | 70 | 2021 |
Native SILAC: metabolic labeling of proteins in prototroph microorganisms based on lysine synthesis regulation F Fröhlich, R Christiano, TC Walther Molecular & Cellular Proteomics 12 (7), 1995-2005, 2013 | 67 | 2013 |