| X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease S Günther, PYA Reinke, Y Fernández-García, J Lieske, TJ Lane, HM Ginn, ... Science 372 (6542), 642-646, 2021 | 289 | 2021 |
| All three domains of the hepatitis C virus nonstructural NS5A protein contribute to RNA binding TL Foster, T Belyaeva, NJ Stonehouse, AR Pearson, M Harris Journal of virology 84 (18), 9267-9277, 2010 | 154 | 2010 |
| MauG, a novel diheme protein required for tryptophan tryptophylquinone biogenesis Y Wang, ME Graichen, A Liu, AR Pearson, CM Wilmot, VL Davidson Biochemistry 42 (24), 7318-7325, 2003 | 149 | 2003 |
| Using synchrotrons and XFELs for time-resolved X-ray crystallography and solution scattering experiments on biomolecules M Levantino, BA Yorke, DCF Monteiro, M Cammarata, AR Pearson Current opinion in structural biology 35, 41-48, 2015 | 140 | 2015 |
| Fixed target matrix for femtosecond time-resolved and in situ serial micro-crystallography C Mueller, A Marx, SW Epp, Y Zhong, A Kuo, AR Balo, J Soman, F Schotte, ... Structural Dynamics 2 (5), 2015 | 139 | 2015 |
| Nature of the ferryl heme in compounds I and II A Gumiero, CL Metcalfe, AR Pearson, EL Raven, PCE Moody Journal of biological chemistry 286 (2), 1260-1268, 2011 | 121 | 2011 |
| Packaging signals in single-stranded RNA viruses: nature’s alternative to a purely electrostatic assembly mechanism PG Stockley, R Twarock, SE Bakker, AM Barker, A Borodavka, ... Journal of biological physics 39, 277-287, 2013 | 112 | 2013 |
| Complex interplay between epitope specificity and isotype dictates the biological activity of anti-human CD40 antibodies X Yu, HTC Chan, CM Orr, O Dadas, SG Booth, LN Dahal, CA Penfold, ... Cancer cell 33 (4), 664-675. e4, 2018 | 98 | 2018 |
| Exploring molecular oxygen pathways in Hansenula polymorpha copper-containing amine oxidase BJ Johnson, J Cohen, RW Welford, AR Pearson, K Schulten, JP Klinman, ... Journal of Biological Chemistry 282 (24), 17767-17776, 2007 | 96 | 2007 |
| Fixed target combined with spectral mapping: approaching 100% hit rates for serial crystallography S Oghbaey, A Sarracini, HM Ginn, O Pare-Labrosse, A Kuo, A Marx, ... Acta Crystallographica Section D: Structural Biology 72 (8), 944-955, 2016 | 95 | 2016 |
| Liquid application method for time-resolved analyses by serial synchrotron crystallography P Mehrabi, EC Schulz, M Agthe, S Horrell, G Bourenkov, D von Stetten, ... Nature methods 16 (10), 979-982, 2019 | 94 | 2019 |
| Further insights into quinone cofactor biogenesis: probing the role of mauG in methylamine dehydrogenase tryptophan tryptophylquinone formation AR Pearson, T De la Mora-Rey, ME Graichen, Y Wang, LH Jones, ... Biochemistry 43 (18), 5494-5502, 2004 | 92 | 2004 |
| Serial synchrotron crystallography for time-resolved structural biology AR Pearson, P Mehrabi Current Opinion in Structural Biology 65, 168-174, 2020 | 81 | 2020 |
| Improving Escherichia coli alkaline phosphatase efficacy by additional mutations inside and outside the catalytic pocket BH Muller, C Lamoure, MH Le Du, L Cattolico, E Lajeunesse, F Lemaître, ... Chembiochem 2 (7‐8), 517-523, 2001 | 79 | 2001 |
| X-ray-based techniques to study the nano–bio interface C Sanchez-Cano, RA Alvarez-Puebla, JM Abendroth, T Beck, R Blick, ... ACS nano 15 (3), 3754-3807, 2021 | 76 | 2021 |
| Structure‐guided design affirms inhibitors of hepatitis C virus p7 as a viable class of antivirals targeting virion release TL Foster, GS Thompson, AP Kalverda, J Kankanala, M Bentham, ... Hepatology 59 (2), 408-422, 2014 | 67 | 2014 |
| MauG-dependent in vitro biosynthesis of tryptophan tryptophylquinone in methylamine dehydrogenase Y Wang, X Li, LH Jones, AR Pearson, CM Wilmot, VL Davidson Journal of the American Chemical Society 127 (23), 8258-8259, 2005 | 66 | 2005 |
| The Crystal Structure of Cytochrome P460 of Nitrosomonas europaea Reveals a Novel Cytochrome Fold and Heme−Protein Cross-link, AR Pearson, BO Elmore, C Yang, JD Ferrara, AB Hooper, CM Wilmot Biochemistry 46 (28), 8340-8349, 2007 | 63 | 2007 |
| The HARE chip for efficient time-resolved serial synchrotron crystallography P Mehrabi, HM Müller-Werkmeister, JP Leimkohl, H Schikora, J Ninkovic, ... Journal of synchrotron radiation 27 (2), 360-370, 2020 | 57 | 2020 |
| Structural insight into methyl-coenzyme M reductase chemistry using coenzyme B analogues PE Cedervall, M Dey, AR Pearson, SW Ragsdale, CM Wilmot Biochemistry 49 (35), 7683-7693, 2010 | 57 | 2010 |
