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Timothy M. Miller
Timothy M. Miller
Professor of Neurology, Washington University
Dirección de correo verificada de wustl.edu - Página principal
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Unraveling the mechanisms involved in motor neuron degeneration in ALS
LI Bruijn, TM Miller, DW Cleveland
Annu. Rev. Neurosci. 27 (1), 723-749, 2004
16892004
Distinct tau prion strains propagate in cells and mice and define different tauopathies
DW Sanders, SK Kaufman, SL DeVos, AM Sharma, H Mirbaha, A Li, ...
Neuron 82 (6), 1271-1288, 2014
10422014
Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
BB Holmes, SL DeVos, N Kfoury, M Li, R Jacks, K Yanamandra, ...
Proceedings of the National Academy of Sciences 110 (33), E3138-E3147, 2013
9022013
RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia
T Zu, Y Liu, M Bañez-Coronel, T Reid, O Pletnikova, J Lewis, TM Miller, ...
Proceedings of the National Academy of Sciences 110 (51), E4968-E4977, 2013
8782013
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
I Wegorzewska, S Bell, NJ Cairns, TM Miller, RH Baloh
Proceedings of the National Academy of Sciences 106 (44), 18809-18814, 2009
8282009
An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study
TM Miller, A Pestronk, W David, J Rothstein, E Simpson, SH Appel, ...
The Lancet Neurology 12 (5), 435-442, 2013
7032013
Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria
J Liu, C Lillo, PA Jonsson, CV Velde, CM Ward, TM Miller, ...
Neuron 43 (1), 5-17, 2004
6502004
Genome-wide analyses identify KIF5A as a novel ALS gene
A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ...
Neuron 97 (6), 1267-1288, 2018
6332018
C9orf72 is required for proper macrophage and microglial function in mice
JG O’rourke, L Bogdanik, A Yáñez, D Lall, AJ Wolf, A Muhammad, R Ho, ...
Science 351 (6279), 1324-1329, 2016
6132016
Antisense oligonucleotide therapy for neurodegenerative disease
RA Smith, TM Miller, K Yamanaka, BP Monia, TP Condon, G Hung, ...
The Journal of clinical investigation 116 (8), 2290-2296, 2006
6112006
Tau kinetics in neurons and the human central nervous system
C Sato, NR Barthélemy, KG Mawuenyega, BW Patterson, BA Gordon, ...
Neuron 97 (6), 1284-1298. e7, 2018
5692018
Phase 1–2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS
T Miller, M Cudkowicz, PJ Shaw, PM Andersen, N Atassi, RC Bucelli, ...
New England Journal of Medicine 383 (2), 109-119, 2020
4962020
Trial of sodium phenylbutyrate–taurursodiol for amyotrophic lateral sclerosis
S Paganoni, EA Macklin, S Hendrix, JD Berry, MA Elliott, S Maiser, ...
New England Journal of Medicine 383 (10), 919-930, 2020
4892020
Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy
SL DeVos, RL Miller, KM Schoch, BB Holmes, CS Kebodeaux, ...
Science translational medicine 9 (374), eaag0481, 2017
4612017
Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death
TM Miller, KL Moulder, CM Knudson, DJ Creedon, M Deshmukh, ...
The Journal of cell biology 139 (1), 205-217, 1997
4581997
Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS
TM Miller, ME Cudkowicz, A Genge, PJ Shaw, G Sobue, RC Bucelli, ...
New England Journal of Medicine 387 (12), 1099-1110, 2022
4462022
Tau prion strains dictate patterns of cell pathology, progression rate, and regional vulnerability in vivo
SK Kaufman, DW Sanders, TL Thomas, AJ Ruchinskas, J Vaquer-Alicea, ...
Neuron 92 (4), 796-812, 2016
4322016
Myopathy with antibodies to the signal recognition particle: clinical and pathological features
T Miller, MT Al-Lozi, G Lopate, A Pestronk
Journal of Neurology, Neurosurgery & Psychiatry 73 (4), 420-428, 2002
3782002
Antisense reduction of tau in adult mice protects against seizures
SL DeVos, DK Goncharoff, G Chen, CS Kebodeaux, K Yamada, ...
Journal of Neuroscience 33 (31), 12887-12897, 2013
3552013
Muscle cramps
TM Miller, RB Layzer
Muscle & Nerve: Official Journal of the American Association of …, 2005
3532005
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20