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Riccardo Mezzadra
Riccardo Mezzadra
Dirección de correo verificada de mskcc.org
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Mutations associated with acquired resistance to PD-1 blockade in melanoma
JM Zaretsky, A Garcia-Diaz, DS Shin, H Escuin-Ordinas, W Hugo, ...
New England Journal of Medicine 375 (9), 819-829, 2016
30582016
Regulation and function of the PD-L1 checkpoint
C Sun, R Mezzadra, TN Schumacher
Immunity 48 (3), 434-452, 2018
18712018
Identification of CMTM6 and CMTM4 as PD-L1 protein regulators
R Mezzadra, C Sun, LT Jae, R Gomez-Eerland, E De Vries, W Wu, ...
Nature 549 (7670), 106-110, 2017
6102017
Low and variable tumor reactivity of the intratumoral TCR repertoire in human cancers
W Scheper, S Kelderman, LF Fanchi, C Linnemann, G Bendle, ...
Nature medicine 25 (1), 89-94, 2019
5252019
Senescence-induced vascular remodeling creates therapeutic vulnerabilities in pancreas cancer
M Ruscetti, JP Morris, R Mezzadra, J Russell, J Leibold, PB Romesser, ...
Cell 181 (2), 424-441. e21, 2020
2812020
Lentiviral vector integration in the human genome induces alternative splicing and generates aberrant transcripts
A Moiani, Y Paleari, D Sartori, R Mezzadra, A Miccio, C Cattoglio, ...
The Journal of clinical investigation 122 (5), 1653-1666, 2012
2122012
Augmenting immunotherapy impact by lowering tumor TNF cytotoxicity threshold
DW Vredevoogd, T Kuilman, MA Ligtenberg, J Boshuizen, KE Stecker, ...
Cell 178 (3), 585-599. e15, 2019
1962019
Correction of β‐thalassemia major by gene transfer in haematopoietic progenitors of pediatric patients
EA Roselli, R Mezzadra, MC Frittoli, G Maruggi, E Biral, F Mavilio, ...
EMBO molecular medicine 2 (8), 315-328, 2010
1212010
Senescence rewires microenvironment sensing to facilitate antitumor immunity
HA Chen, YJ Ho, R Mezzadra, JM Adrover, R Smolkin, C Zhu, K Woess, ...
Cancer discovery 13 (2), 432-453, 2023
912023
TCR repertoires of intratumoral T‐cell subsets
C Linnemann, R Mezzadra, TNM Schumacher
Immunological reviews 257 (1), 72-82, 2014
782014
Molecular Characterization of Acquired Resistance to KRASG12C–EGFR Inhibition in Colorectal Cancer
R Yaeger, R Mezzadra, J Sinopoli, Y Bian, M Marasco, E Kaplun, Y Gao, ...
Cancer discovery 13 (1), 41-55, 2023
482023
SLFN11 can sensitize tumor cells towards IFN-γ-mediated T cell killing
R Mezzadra, M de Bruijn, LT Jae, R Gomez-Eerland, A Duursma, ...
PLoS One 14 (2), e0212053, 2019
392019
Increased p53 expression induced by APR-246 reprograms tumor-associated macrophages to augment immune checkpoint blockade
A Ghosh, J Michels, R Mezzadra, D Venkatesh, L Dong, R Gomez, ...
The Journal of Clinical Investigation 132 (18), 2022
122022
CMTM6 shapes antitumor T cell response through modulating protein expression of CD58 and PD-L1
B Miao, Z Hu, R Mezzadra, L Hoeijmakers, A Fauster, S Du, Z Yang, ...
Cancer cell 41 (10), 1817-1828. e9, 2023
82023
A Traceless Selection: Counter-selection System That Allows Efficient Generation of Transposon and CRISPR-modified T-cell Products
R Mezzadra, A Hollenstein, R Gomez-Eerland, TN Schumacher
Molecular Therapy-Nucleic Acids 5, 2016
42016
Molecular characterization of acquired resistance to KRAS G12C inhibition in gastrointestinal cancers
S Misale, R Yaeger, R Mezzadra, J Sinopoli, Y Bian, M Marasco, ...
12022
Abstract B188: CMTM6, beyond a regulator of PD-L1 expression
C Sun, R Mezzadra, R Gomez-Eerland, I Hofland, D Peters, A Broeks, ...
Cancer Immunology Research 7 (2_Supplement), B188-B188, 2019
2019
Genetic manipulation and genetic-based dissection of tumor-specific immunity
R Mezzadra
cell 33 (2015), 2014
2014
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Artículos 1–18