| Disease-modifying treatments for osteoarthritis (DMOADs) of the knee and hip: lessons learned from failures and opportunities for the future MA Karsdal, M Michaelis, C Ladel, AS Siebuhr, AR Bihlet, JR Andersen, ... Osteoarthritis and cartilage 24 (12), 2013-2021, 2016 | 344 | 2016 |
| Effect of intra-articular sprifermin vs placebo on femorotibial joint cartilage thickness in patients with osteoarthritis: the FORWARD randomized clinical trial MC Hochberg, A Guermazi, H Guehring, A Aydemir, S Wax, ... Jama 322 (14), 1360-1370, 2019 | 261 | 2019 |
| Treatment of symptomatic knee osteoarthritis with oral salmon calcitonin: results from two phase 3 trials MA Karsdal, I Byrjalsen, P Alexandersen, A Bihlet, JR Andersen, BJ Riis, ... Osteoarthritis and cartilage 23 (4), 532-543, 2015 | 149 | 2015 |
| A randomized, double-blind, multicenter, placebo-controlled study to evaluate the efficacy and safety of oral salmon calcitonin in the treatment of osteoporosis in … K Henriksen, I Byrjalsen, JR Andersen, AR Bihlet, LA Russo, ... Bone 91, 122-129, 2016 | 88 | 2016 |
| Biomarkers of extracellular matrix turnover are associated with emphysema and eosinophilic-bronchitis in COPD AR Bihlet, MA Karsdal, JMB Sand, DJ Leeming, M Roberts, W White, ... Respiratory Research 18, 1-11, 2017 | 75 | 2017 |
| OA phenotypes, rather than disease stage, drive structural progression–identification of structural progressors from 2 phase III randomized clinical studies with symptomatic … MA Karsdal, A Bihlet, I Byrjalsen, P Alexandersen, C Ladel, M Michaels, ... Osteoarthritis and cartilage 23 (4), 550-558, 2015 | 74 | 2015 |
| High levels of biomarkers of collagen remodeling are associated with increased mortality in COPD–results from the ECLIPSE study JMB Sand, DJ Leeming, I Byrjalsen, AR Bihlet, P Lange, R Tal-Singer, ... Respiratory research 17, 1-12, 2016 | 65 | 2016 |
| The impact of clinical trial monitoring approaches on data integrity and cost—a review of current literature R Olsen, AR Bihlet, F Kalakou, JR Andersen European journal of clinical pharmacology 72, 399-412, 2016 | 65 | 2016 |
| Impact of source data verification on data quality in clinical trials: an empirical post hoc analysis of three phase 3 randomized clinical trials JR Andersen, I Byrjalsen, A Bihlet, F Kalakou, HC Hoeck, G Hansen, ... British journal of clinical pharmacology 79 (4), 660-668, 2015 | 57 | 2015 |
| Long-term structural and symptomatic effects of intra-articular sprifermin in patients with knee osteoarthritis: 5-year results from the FORWARD study F Eckstein, MC Hochberg, H Guehring, F Moreau, V Ona, AR Bihlet, ... Annals of the Rheumatic Diseases 80 (8), 1062-1069, 2021 | 55 | 2021 |
| Associations between biomarkers of bone and cartilage turnover, gender, pain categories and radiographic severity in knee osteoarthritis AR Bihlet, I Byrjalsen, AC Bay-Jensen, JR Andersen, C Christiansen, ... Arthritis research & therapy 21, 1-10, 2019 | 43 | 2019 |
| Protein biomarkers associated with pain mechanisms in osteoarthritis CS Thudium, H Löfvall, MA Karsdal, AC Bay-Jensen, AR Bihlet Journal of proteomics 190, 55-66, 2019 | 35 | 2019 |
| Efficacy and safety of intra-articular Sprifermin in symptomatic radiographic knee osteoarthritis: pre-specified analysis of 3-year data from a 5-year randomized, placebo … M Hochberg, A Guermazi, H Guehring, A Aydemir, S Wax, ... Osteoarthritis and Cartilage 26, S26-S27, 2018 | 33* | 2018 |
| The effects of sprifermin on symptoms and structure in a subgroup at risk of progression in the FORWARD knee osteoarthritis trial H Guehring, F Moreau, B Daelken, C Ladel, O Guenther, AR Bihlet, ... Seminars in Arthritis and Rheumatism 51 (2), 450-456, 2021 | 25 | 2021 |
| Serum C-reactive protein metabolite (CRPM) is associated with incidence of contralateral knee osteoarthritis AC Bay-Jensen, A Bihlet, I Byrjalsen, JR Andersen, BJ Riis, ... Scientific Reports 11 (1), 6583, 2021 | 23 | 2021 |
| Clinical and biochemical factors associated with risk of total joint replacement and radiographic progression in osteoarthritis: data from two phase III clinical trials AR Bihlet, JJ Bjerre-Bastos, JR Andersen, I Byrjalsen, MA Karsdal, ... Seminars in Arthritis and Rheumatism 50 (6), 1374-1381, 2020 | 21 | 2020 |
| Matrix metalloproteinase mediated type I collagen degradation is an independent predictor of increased risk of acute myocardial infarction in postmenopausal women DM Bertelsen, JS Neergaard, CL Bager, SH Nielsen, NH Secher, ... Scientific reports 8 (1), 5371, 2018 | 21 | 2018 |
| Biomarkers of collagen turnover are related to annual change in FEV1 in patients with chronic obstructive pulmonary disease within the ECLIPSE study DJ Leeming, I Byrjalsen, JMB Sand, AR Bihlet, P Lange, R Thal-Singer, ... BMC pulmonary medicine 17, 1-10, 2017 | 21 | 2017 |
| Clinical drug development using dynamic biomarkers to enable personalized health care in COPD AR Bihlet, MA Karsdal, AC Bay-Jensen, S Read, JH Kristensen, ... Chest 148 (1), 16-23, 2015 | 21 | 2015 |
| Cohort profile: the prospective epidemiological risk factor (PERF) study JS Neergaard, K Dragsbæk, SN Kehlet, HB Hansen, G Hansen, ... International Journal of Epidemiology 46 (4), 1104-1104i, 2017 | 20 | 2017 |
