| Applications of hydrogen/deuterium exchange MS from 2012 to 2014 GF Pirrone, RE Iacob, JR Engen Analytical chemistry 87 (1), 99-118, 2015 | 173 | 2015 |
| Evaluation of global conformational changes in peptides and proteins following purification by supercritical fluid chromatography NM Schiavone, R Bennett, MB Hicks, GF Pirrone, EL Regalado, I Mangion, ... Journal of Chromatography B 1110, 94-100, 2019 | 41 | 2019 |
| Conformational transition of membrane-associated terminally acylated HIV-1 Nef B Akgun, S Satija, H Nanda, GF Pirrone, X Shi, JR Engen, MS Kent Structure 21 (10), 1822-1833, 2013 | 40 | 2013 |
| Multi-column ultra-high performance liquid chromatography screening with chaotropic agents and computer-assisted separation modeling enables process development of new drug … IAH Ahmad, W Chen, HM Halsey, A Klapars, J Limanto, GF Pirrone, ... Analyst 144 (9), 2872-2880, 2019 | 35 | 2019 |
| Supercritical fluid chromatography-photodiode array detection-electrospray ionization mass spectrometry as a framework for impurity fate mapping in the development and … GF Pirrone, RM Mathew, AA Makarov, F Bernardoni, A Klapars, ... Journal of Chromatography B 1080, 42-49, 2018 | 33 | 2018 |
| Use of MALDI-MS combined with differential hydrogen–deuterium exchange for semiautomated protein global conformational screening GF Pirrone, H Wang, N Canfield, AS Chin, TA Rhodes, AA Makarov Analytical Chemistry 89 (16), 8351-8357, 2017 | 24 | 2017 |
| Hydrogen exchange mass spectrometry of proteins at Langmuir monolayers GF Pirrone, BC Vernon, MS Kent, JR Engen Analytical chemistry 87 (14), 7022-7029, 2015 | 21 | 2015 |
| Membrane-associated conformation of HIV-1 Nef investigated with hydrogen exchange mass spectrometry at a Langmuir monolayer GF Pirrone, LA Emert-Sedlak, TE Wales, TE Smithgall, MS Kent, ... Analytical chemistry 87 (14), 7030-7035, 2015 | 19 | 2015 |
| Manufacturing process development for belzutifan, part 3: Completing a streamlined through-process with a safe and scalable oxidation Z Chen, N Salehi Marzijarani, S Quirie, GF Pirrone, SM Dalby, T Wang, ... Organic Process Research & Development 26 (3), 525-532, 2021 | 17 | 2021 |
| Ultra-high-throughput SPE-MALDI workflow: Blueprint for efficient purification and screening of peptide libraries R Bennett, GF Pirrone, T Nowak, D Mukherjee, V Shchurik, C Mapelli, ... Analytica Chimica Acta 1142, 10-18, 2021 | 15 | 2021 |
| Use of MALDI-MS with solid-state hydrogen deuterium exchange for semi-automated assessment of peptide and protein physical stability in lyophilized solids SR Kabaria, I Mangion, AA Makarov, GF Pirrone Analytica chimica acta 1054, 114-121, 2019 | 15 | 2019 |
| Visualizing and studying frictional heating effects in reversed-phase liquid chromatography using infrared thermal imaging AA Makarov, BF Mann, EL Regalado, GF Pirrone, C Sun, S Sun, T Nowak, ... Analytica chimica acta 1018, 1-6, 2018 | 14 | 2018 |
| Combination of circular dichroism spectroscopy and size-exclusion chromatography coupled with HDX-MS for studying global conformational structures of peptides in solution NM Schiavone, GF Pirrone, ED Guetschow, I Mangion, AA Makarov Talanta 194, 177-182, 2019 | 13 | 2019 |
| Liposome Artificial Membrane Permeability Assay by MALDI-hydrogen-deuterium exchange mass spectrometry for peptides and small proteins AA Makarov, GF Pirrone, V Shchurik, EL Regalado, I Mangion Analytica chimica acta 1099, 111-118, 2020 | 11 | 2020 |
| Combination of HDX-MS and in silico modeling to study enzymatic reactivity and stereo-selectivity at different solvent conditions AA Makarov, RE Iacob, GF Pirrone, A Rodriguez-Granillo, L Joyce, ... Journal of Pharmaceutical and Biomedical Analysis 182, 113141, 2020 | 7 | 2020 |
| Rapid label-free cell-based Approach Membrane Permeability Assay using MALDI-hydrogen-deuterium exchange mass spectrometry for peptides AA Makarov, Y Jiang, C Sondey, M Zhang, MS Mansueto, GF Pirrone, ... Analytica Chimica Acta 1225, 340234, 2022 | 6 | 2022 |
| Rapid antibody conformational screening by matrix‐assisted laser desorption/ionization hydrogen‐deuterium exchange mass spectrometry D Mukherjee, P Trigo‐Mouriño, Y Jiang, T Nowak, V Shchurik, ... Journal of Separation Science 45 (12), 2055-2063, 2022 | 4 | 2022 |
| Synthesis and characterization of a deuterium labeled stercobilin: A potential biomarker for autism JM Coffey, AJ Vadas, TR Puleo, KP Lewis, GF Pirrone, HL Rudolph, ... Journal of Labelled Compounds and Radiopharmaceuticals 61 (10), 742-748, 2018 | 3 | 2018 |
| Automated High-Throughput Matrix Assisted Laser Desorption Ionization Mass Spectrometry Methodology for Formulation Assessment of Polyethylene-Glycol-Conjugated Cytokine Proteins GF Pirrone, EV Munsell, HM Ferguson, MA Al-Sayah, SA Luthra, ... Journal of Pharmaceutical Sciences 112 (11), 2778-2782, 2023 | | 2023 |
| Strategies for MALDI-MS method development to investigate different pharmaceutical drug modalities D Mukherjee, T Nowak, V Shchurik, GF Pirrone, MA Al-Sayah, ... International Journal of Mass Spectrometry 493, 117116, 2023 | | 2023 |
Alexey A MakarovAnalytical Research & Development, Merck & Co., Inc.Verified email at merck.com
