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Katherine L Nathanson
Katherine L Nathanson
Professor of Medicine, Perelman School of Medicine at the University of Pennsylvania
Dirección de correo verificada de upenn.edu
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Año
The tuberous sclerosis complex
PB Crino, KL Nathanson, EP Henske
New England Journal of Medicine 355 (13), 1345-1356, 2006
20342006
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma
G Bollag, P Hirth, J Tsai, J Zhang, PN Ibrahim, H Cho, W Spevak, C Zhang, ...
Nature 467 (7315), 596-599, 2010
20092010
Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K
J Villanueva, A Vultur, JT Lee, R Somasundaram, M Fukunaga-Kalabis, ...
Cancer cell 18 (6), 683-695, 2010
14732010
T-cell invigoration to tumour burden ratio associated with anti-PD-1 response
AC Huang, MA Postow, RJ Orlowski, R Mick, B Bengsch, S Manne, W Xu, ...
Nature 545 (7652), 60-65, 2017
14722017
Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 or BRCA2 mutations.
H Meijers-Heijboer, A Van den Ouweland, J Klijn, M Wasielewski, ...
Nature genetics 31 (1), 2002
13982002
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance
SM Shaffer, MC Dunagin, SR Torborg, EA Torre, B Emert, C Krepler, ...
Nature 546 (7658), 431-435, 2017
10812017
Gene-panel sequencing and the prediction of breast-cancer risk
DF Easton, PDP Pharoah, AC Antoniou, M Tischkowitz, SV Tavtigian, ...
New England Journal of Medicine 372 (23), 2243-2257, 2015
10132015
Cancer risk estimates for BRCA1 mutation carriers identified in a risk evaluation program
MS Brose, TR Rebbeck, KA Calzone, JE Stopfer, KL Nathanson, ...
Journal of the National Cancer Institute 94 (18), 1365-1372, 2002
9672002
Sorafenib in advanced melanoma: a Phase II randomised discontinuation trial analysis
T Eisen, T Ahmad, KT Flaherty, M Gore, S Kaye, R Marais, I Gibbens, ...
British journal of cancer 95 (5), 581-586, 2006
7952006
Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)
N Mavaddat, D Barrowdale, IL Andrulis, SM Domchek, D Eccles, ...
Cancer Epidemiology, Biomarkers & Prevention 21 (1), 134-147, 2012
7552012
Network modeling links breast cancer susceptibility and centrosome dysfunction
MA Pujana, JDJ Han, LM Starita, KN Stevens, M Tewari, JS Ahn, ...
Nature genetics 39 (11), 1338-1349, 2007
7262007
PTEN Mutation Spectrum and Genotype-Phenotype Correlations in Bannayan-Riley-Ruvalcaba Syndrome Suggest a Single Entity With Cowden Syndrome
DJ Marsh, JB Kum, KL Lunetta, MJ Bennett, RJ Gorlin, SF Ahmed, ...
Human molecular genetics 8 (8), 1461-1472, 1999
6681999
Breast cancer genetics: what we know and what we need
KN Nathanson, R Wooster, BL Weber
Nature medicine 7 (5), 552-556, 2001
6482001
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
SE Bojesen, KA Pooley, SE Johnatty, J Beesley, K Michailidou, JP Tyrer, ...
Nature genetics 45 (4), 371-384, 2013
6452013
PTEN loss confers BRAF inhibitor resistance to melanoma cells through the suppression of BIM expression
KHT Paraiso, Y Xiang, VW Rebecca, EV Abel, YA Chen, AC Munko, ...
Cancer research 71 (7), 2750-2760, 2011
6402011
Comprehensive molecular characterization of pheochromocytoma and paraganglioma
L Fishbein, I Leshchiner, V Walter, L Danilova, AG Robertson, ...
Cancer cell 31 (2), 181-193, 2017
6242017
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature
KS Hoek, NC Schlegel, P Brafford, A Sucker, S Ugurel, R Kumar, ...
Pigment cell research 19 (4), 290-302, 2006
6022006
HIF-α effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma
JD Gordan, P Lal, VR Dondeti, R Letrero, KN Parekh, CE Oquendo, ...
Cancer cell 14 (6), 435-446, 2008
5832008
A population-based study of genes previously implicated in breast cancer
C Hu, SN Hart, R Gnanaolivu, H Huang, KY Lee, J Na, C Gao, J Lilyquist, ...
New England Journal of Medicine 384 (5), 440-451, 2021
5622021
A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma
AC Huang, RJ Orlowski, X Xu, R Mick, SM George, PK Yan, S Manne, ...
Nature medicine 25 (3), 454-461, 2019
5472019
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