Darrell J. Irvine
Darrell J. Irvine
Verified email at mit.edu - Homepage
Cited by
Cited by
Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
CM Metallo, PA Gameiro, EL Bell, KR Mattaini, J Yang, K Hiller, ...
Nature 481 (7381), 380-384, 2012
Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles
A Verma, O Uzun, Y Hu, Y Hu, HS Han, N Watson, S Chen, DJ Irvine, ...
Nature materials 7 (7), 588-595, 2008
Bio-inspired, bioengineered and biomimetic drug delivery carriers
JW Yoo, DJ Irvine, DE Discher, S Mitragotri
Nature reviews Drug discovery 10 (7), 521-535, 2011
Direct observation of ligand recognition by T cells
DJ Irvine, MA Purbhoo, M Krogsgaard, MM Davis
Nature 419 (6909), 845-849, 2002
Structure-based programming of lymph-node targeting in molecular vaccines
H Liu, KD Moynihan, Y Zheng, GL Szeto, AV Li, B Huang, DS Van Egeren, ...
Nature 507 (7493), 519-522, 2014
T cell killing does not require the formation of a stable mature immunological synapse
MA Purbhoo, DJ Irvine, JB Huppa, MM Davis
Nature immunology 5 (5), 524-530, 2004
Therapeutic cell engineering with surface-conjugated synthetic nanoparticles
MT Stephan, JJ Moon, SH Um, A Bershteyn, DJ Irvine
Nature medicine 16 (9), 1035-1041, 2010
Synthetic nanoparticles for vaccines and immunotherapy
DJ Irvine, MC Hanson, K Rakhra, T Tokatlian
Chemical reviews 115 (19), 11109-11146, 2015
Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses
JJ Moon, H Suh, A Bershteyn, MT Stephan, H Liu, B Huang, M Sohail, ...
Nature materials 10 (3), 243-251, 2011
Co-regulation of cell adhesion by nanoscale RGD organization and mechanical stimulus
LY Koo, DJ Irvine, AM Mayes, DA Lauffenburger, LG Griffith
Journal of cell science 115 (7), 1423-1433, 2002
Engineering synthetic vaccines using cues from natural immunity
DJ Irvine, MA Swartz, GL Szeto
Nature materials 12 (11), 978-990, 2013
Engineering nano‐and microparticles to tune immunity
JJ Moon, B Huang, DJ Irvine
Advanced materials 24 (28), 3724-3746, 2012
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses
KD Moynihan, CF Opel, GL Szeto, A Tzeng, EF Zhu, JM Engreitz, ...
Nature medicine 22 (12), 1402-1410, 2016
Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction
JJ Moon, H Suh, AV Li, CF Ockenhouse, A Yadava, DJ Irvine
Proceedings of the National Academy of Sciences 109 (4), 1080-1085, 2012
Cytosolic delivery of membrane-impermeable molecules in dendritic cells using pH-responsive core− shell nanoparticles
Y Hu, T Litwin, AR Nagaraja, B Kwong, J Katz, N Watson, DJ Irvine
Nano letters 7 (10), 3056-3064, 2007
CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse
QJ Li, AR Dinner, S Qi, DJ Irvine, JB Huppa, MM Davis, AK Chakraborty
Nature immunology 5 (8), 791-799, 2004
Particulate vaccines: on the quest for optimal delivery and immune response
ML De Temmerman, J Rejman, J Demeester, DJ Irvine, B Gander, ...
Drug discovery today 16 (13-14), 569-582, 2011
A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples
ME Ackerman, B Moldt, RT Wyatt, AS Dugast, E McAndrew, S Tsoukas, ...
Journal of immunological methods 366 (1-2), 8-19, 2011
Nanoscale clustering of RGD peptides at surfaces using comb polymers. 1. Synthesis and characterization of comb thin films
DJ Irvine, AM Mayes, LG Griffith
Biomacromolecules 2 (1), 85-94, 2001
In Vitro and in Vivo mRNA Delivery Using Lipid-Enveloped pH-Responsive Polymer Nanoparticles
X Su, J Fricke, DG Kavanagh, DJ Irvine
Molecular pharmaceutics 8 (3), 774-787, 2011
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