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François Bordeleau
François Bordeleau
Université Laval, Département de biologie moléculaire, de biochimie médicale et de pathologie
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Matrix stiffening promotes a tumor vasculature phenotype
F Bordeleau, BN Mason, EM Lollis, M Mazzola, MR Zanotelli, ...
Proceedings of the National Academy of Sciences 114 (3), 492-497, 2017
3682017
Microvesicles provide a mechanism for intercellular communication by embryonic stem cells during embryo implantation
LM Desrochers, F Bordeleau, CA Reinhart-King, RA Cerione, ...
Nature communications 7 (1), 11958, 2016
2092016
Cooperative effects of matrix stiffness and fluid shear stress on endothelial cell behavior
JC Kohn, DW Zhou, F Bordeleau, AL Zhou, BN Mason, MJ Mitchell, ...
Biophysical journal 108 (3), 471-478, 2015
1732015
Energetic regulation of coordinated leader–follower dynamics during collective invasion of breast cancer cells
J Zhang, KF Goliwas, W Wang, PV Taufalele, F Bordeleau, ...
Proceedings of the National Academy of Sciences 116 (16), 7867-7872, 2019
1502019
Targeted inhibition of fascin function blocks tumour invasion and metastatic colonization
FK Huang, S Han, B Xing, J Huang, B Liu, F Bordeleau, CA Reinhart-King, ...
Nature communications 6 (1), 7465, 2015
1342015
Regulation of ATP utilization during metastatic cell migration by collagen architecture
MR Zanotelli, ZE Goldblatt, JP Miller, F Bordeleau, J Li, JA VanderBurgh, ...
Molecular biology of the cell 29 (1), 1-9, 2018
1312018
Energetic costs regulated by cell mechanics and confinement are predictive of migration path during decision-making
MR Zanotelli, A Rahman-Zaman, JA VanderBurgh, PV Taufalele, A Jain, ...
Nature communications 10 (1), 4185, 2019
1302019
Keratin 8/18 modulation of protein kinase C-mediated integrin-dependent adhesion and migration of liver epithelial cells
F Bordeleau, L Galarneau, S Gilbert, A Loranger, N Marceau
Molecular biology of the cell 21 (10), 1698-1713, 2010
942010
Tissue stiffness regulates serine/arginine-rich protein-mediated splicing of the extra domain B-fibronectin isoform in tumors
F Bordeleau, JP Califano, YL Negrón Abril, BN Mason, DJ LaValley, ...
Proceedings of the National Academy of Sciences 112 (27), 8314-8319, 2015
922015
Keratin 8/18 regulation of cell stiffness-extracellular matrix interplay through modulation of Rho-mediated actin cytoskeleton dynamics
F Bordeleau, MEM Lapierre, Y Sheng, N Marceau
PLOS ONE 7 (6), e38780, 2012
882012
Improving fascin inhibitors to block tumor cell migration and metastasis
S Han, J Huang, B Liu, B Xing, F Bordeleau, CA Reinhart-King, W Li, ...
Molecular oncology 10 (7), 966-980, 2016
812016
Matrix stiffness enhances VEGFR-2 internalization, signaling, and proliferation in endothelial cells
DJ LaValley, MR Zanotelli, F Bordeleau, W Wang, SC Schwager, ...
Convergent Science Physical Oncology 3 (4), 044001, 2017
772017
Vinculin regulates directionality and cell polarity in two-and three-dimensional matrix and three-dimensional microtrack migration
A Rahman, SP Carey, CM Kraning-Rush, ZE Goldblatt, F Bordeleau, ...
Molecular biology of the cell 27 (9), 1431-1441, 2016
692016
Matrix stiffness regulates vascular integrity through focal adhesion kinase activity
W Wang, EM Lollis, F Bordeleau, CA Reinhart-King
The FASEB Journal 33 (1), 1199, 2019
632019
Topographical guidance of 3D tumor cell migration at an interface of collagen densities
F Bordeleau, LN Tang, CA Reinhart-King
Physical biology 10 (6), 065004, 2013
582013
Simvastatin ameliorates matrix stiffness-mediated endothelial monolayer disruption
MC Lampi, CJ Faber, J Huynh, F Bordeleau, MR Zanotelli, ...
PLoS One 11 (1), e0147033, 2016
522016
Keratin contribution to cellular mechanical stress response at focal adhesions as assayed by laser tweezers
F Bordeleau, J Bessard, Y Sheng, N Marceau
Biochemistry and cell biology 86 (4), 352-359, 2008
452008
Physical biology in cancer. 5. The rocky road of metastasis: the role of cytoskeletal mechanics in cell migratory response to 3D matrix topography
F Bordeleau, TA Alcoser, CA Reinhart-King
American journal of physiology-Cell physiology 306 (2), C110-C120, 2014
432014
Clinical doses of radiation reduce collagen matrix stiffness
JP Miller, BH Borde, F Bordeleau, MR Zanotelli, DJ LaValley, DJ Parker, ...
APL bioengineering 2 (3), 2018
412018
Matrix stiffness regulates microvesicle-induced fibroblast activation
SC Schwager, F Bordeleau, J Zhang, MA Antonyak, RA Cerione, ...
American Journal of Physiology-Cell Physiology 317 (1), C82-C92, 2019
402019
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