In situ capture of chromatin interactions by biotinylated dCas9 X Liu, Y Zhang, Y Chen, M Li, F Zhou, K Li, H Cao, M Ni, Y Liu, Z Gu, ... Cell 170 (5), 1028-1043. e19, 2017 | 308 | 2017 |
The mitochondrial respiratory chain is essential for haematopoietic stem cell function E Ansó, SE Weinberg, LP Diebold, BJ Thompson, S Malinge, ... Nature cell biology 19 (6), 614-625, 2017 | 289 | 2017 |
Dynamic control of enhancer repertoires drives lineage and stage-specific transcription during hematopoiesis J Huang, X Liu, D Li, Z Shao, H Cao, Y Zhang, E Trompouki, TV Bowman, ... Developmental cell 36 (1), 9-23, 2016 | 243 | 2016 |
Dissecting super-enhancer hierarchy based on chromatin interactions J Huang, K Li, W Cai, X Liu, Y Zhang, SH Orkin, J Xu, GC Yuan Nature communications 9 (1), 943, 2018 | 226 | 2018 |
Interrogation of enhancer function by enhancer-targeting CRISPR epigenetic editing K Li, Y Liu, H Cao, Y Zhang, Z Gu, X Liu, A Yu, P Kaphle, KE Dickerson, ... Nature communications 11 (1), 485, 2020 | 212 | 2020 |
Regulation of mitochondrial biogenesis in erythropoiesis by mTORC1-mediated protein translation X Liu, Y Zhang, M Ni, H Cao, RAJ Signer, D Li, M Li, Z Gu, Z Hu, ... Nature cell biology 19 (6), 626-638, 2017 | 152 | 2017 |
Loss of EZH2 reprograms BCAA metabolism to drive leukemic transformation Z Gu, Y Liu, F Cai, MK Patrick, J Zmajkovic, H Cao, Y Zhang, A Tasdogan, ... Cancer discovery 9 (9), 1228-1247, 2019 | 143 | 2019 |
Regulation of embryonic haematopoietic multipotency by EZH1 LT Vo, MA Kinney, X Liu, Y Zhang, J Barragan, PM Sousa, DK Jha, A Han, ... Nature 553 (7689), 506-510, 2018 | 93 | 2018 |
NF-κB signaling relieves negative regulation by miR-194 in hepatocellular carcinoma by suppressing the transcription factor HNF-1α C Bao, Y Li, L Huan, Y Zhang, F Zhao, Q Wang, L Liang, J Ding, L Liu, ... Science signaling 8 (387), ra75-ra75, 2015 | 88 | 2015 |
Silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia Z Gu, Y Liu, Y Zhang, H Cao, J Lyu, X Wang, A Wylie, SJ Newkirk, ... Nature genetics 53 (5), 672-682, 2021 | 69 | 2021 |
Upregulation of miR‐23a∼ 27a∼ 24 decreases transforming growth factor‐beta‐induced tumor‐suppressive activities in human hepatocellular carcinoma cells S Huang, X He, J Ding, L Liang, Y Zhao, Z Zhang, X Yao, Z Pan, P Zhang, ... International Journal of Cancer 123 (4), 972-978, 2008 | 50 | 2008 |
GATA/heme multi-omics reveals a trace metal-dependent cellular differentiation mechanism N Tanimura, R Liao, GM Wilson, MR Dent, M Cao, JN Burstyn, P Hematti, ... Developmental cell 46 (5), 581-594. e4, 2018 | 39 | 2018 |
Multiplexed capture of spatial configuration and temporal dynamics of locus-specific 3D chromatin by biotinylated dCas9 X Liu, Y Chen, Y Zhang, Y Liu, N Liu, GA Botten, H Cao, SH Orkin, ... Genome biology 21, 1-20, 2020 | 36 | 2020 |
Noncoding variants connect enhancer dysregulation with nuclear receptor signaling in hematopoietic malignancies K Li, Y Zhang, X Liu, Y Liu, Z Gu, H Cao, KE Dickerson, M Chen, W Chen, ... Cancer discovery 10 (5), 724-745, 2020 | 36 | 2020 |
Extensive increase of microarray signals in cancers calls for novel normalization assumptions D Wang, L Cheng, M Wang, R Wu, P Li, B Li, Y Zhang, Y Gu, W Zhao, ... Computational biology and chemistry 35 (3), 126-130, 2011 | 31 | 2011 |
Discovering how heme controls genome function through heme-omics R Liao, Y Zheng, X Liu, Y Zhang, G Seim, N Tanimura, GM Wilson, ... Cell reports 31 (13), 2020 | 30 | 2020 |
Light-activated macromolecular phase separation modulates transcription by reconfiguring chromatin interactions YJ Kim, M Lee Jr, YT Lee, J Jing, JT Sanders, GA Botten, L He, J Lyu, ... Science Advances 9 (13), eadg1123, 2023 | 27 | 2023 |
A unified model of human hemoglobin switching through single-cell genome editing Y Shen, JM Verboon, Y Zhang, N Liu, YJ Kim, S Marglous, ... Nature communications 12 (1), 4991, 2021 | 27 | 2021 |
Temporal dynamics of cardiac hypertrophic growth in response to pressure overload Y Wang, Y Zhang, G Ding, HI May, J Xu, TG Gillette, H Wang, ZV Wang American Journal of Physiology-Heart and Circulatory Physiology 313 (6 …, 2017 | 23 | 2017 |
CAPTURE: In Situ Analysis of Chromatin Composition of Endogenous Genomic Loci by Biotinylated dCas9 X Liu, Y Zhang, Y Chen, M Li, Z Shao, MQ Zhang, J Xu Current protocols in molecular biology 123 (1), e64, 2018 | 21 | 2018 |