| T cell dysfunction in cancer DS Thommen, TN Schumacher Cancer cell 33 (4), 547-562, 2018 | 1053 | 2018 |
| CD8+ T cell states in human cancer: insights from single-cell analysis AM Van der Leun, DS Thommen, TN Schumacher Nature Reviews Cancer 20 (4), 218-232, 2020 | 1047 | 2020 |
| A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade DS Thommen, VH Koelzer, P Herzig, A Roller, M Trefny, S Dimeloe, ... Nature medicine 24 (7), 994-1004, 2018 | 966 | 2018 |
| Tertiary lymphoid structures in cancer TN Schumacher, DS Thommen Science 375 (6576), eabf9419, 2022 | 509 | 2022 |
| Progression of lung cancer is associated with increased dysfunction of T cells defined by coexpression of multiple inhibitory receptors DS Thommen, J Schreiner, P Müller, P Herzig, A Roller, A Belousov, ... Cancer immunology research 3 (12), 1344-1355, 2015 | 394 | 2015 |
| Trastuzumab emtansine (T-DM1) renders HER2+ breast cancer highly susceptible to CTLA-4/PD-1 blockade P Müller, M Kreuzaler, T Khan, DS Thommen, K Martin, K Glatz, S Savic, ... Science translational medicine 7 (315), 315ra188-315ra188, 2015 | 351 | 2015 |
| Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells MA Stanczak, SS Siddiqui, MP Trefny, DS Thommen, KF Boligan, ... The Journal of clinical investigation 128 (11), 4912-4923, 2018 | 256 | 2018 |
| An ex vivo tumor fragment platform to dissect response to PD-1 blockade in cancer P Voabil, M de Bruijn, LM Roelofsen, SH Hendriks, S Brokamp, ... Nature medicine 27 (7), 1250-1261, 2021 | 222 | 2021 |
| Long-distance modulation of bystander tumor cells by CD8+ T-cell-secreted IFN-γ ME Hoekstra, L Bornes, FE Dijkgraaf, D Philips, IN Pardieck, M Toebes, ... Nature cancer 1 (3), 291-301, 2020 | 131 | 2020 |
| Anti-inflammatory drugs remodel the tumor immune environment to enhance immune checkpoint blockade efficacy VS Pelly, A Moeini, LM Roelofsen, E Bonavita, CR Bell, C Hutton, ... Cancer discovery 11 (10), 2602-2619, 2021 | 124 | 2021 |
| IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer OS Blomberg, L Spagnuolo, H Garner, L Voorwerk, OI Isaeva, E van Dyk, ... Cancer Cell 41 (1), 106-123. e10, 2023 | 97 | 2023 |
| Tumor-derived TGF-β inhibits mitochondrial respiration to suppress IFN-γ production by human CD4+ T cells S Dimeloe, P Gubser, J Loeliger, C Frick, L Develioglu, M Fischer, ... Science signaling 12 (599), eaav3334, 2019 | 73 | 2019 |
| The microtubule-depolymerizing agent ansamitocin P3 programs dendritic cells toward enhanced anti-tumor immunity K Martin, P Müller, J Schreiner, SS Prince, D Lardinois, ... Cancer Immunology, Immunotherapy 63, 925-938, 2014 | 73 | 2014 |
| Progression of lung cancer is associated with increased dysfunction of T cells defined by coexpression of multiple inhibitory receptors. Cancer Immunol. Res. 2015; 3: 1344–1355 … DS Thommen, J Schreiner, P Müller, P Herzig, A Roller, A Belousov, ... CIR-15-0097.[Abstract][CrossRef][Google Scholar], 2018 | 72 | 2018 |
| Digital image analysis improves precision of PD‐L1 scoring in cutaneous melanoma VH Koelzer, A Gisler, JC Hanhart, J Griss, SN Wagner, N Willi, ... Histopathology 73 (3), 397-406, 2018 | 70 | 2018 |
| NK cells with tissue-resident traits shape response to immunotherapy by inducing adaptive antitumor immunity N Kirchhammer, MP Trefny, M Natoli, D Brücher, SN Smith, F Werner, ... Science translational medicine 14 (653), eabm9043, 2022 | 44 | 2022 |
| Fibroblast activation protein-targeted-4-1BB ligand agonist amplifies effector functions of intratumoral T cells in human cancer M Trüb, F Uhlenbrock, C Claus, P Herzig, M Thelen, V Karanikas, ... Journal for immunotherapy of cancer 8 (2), 2020 | 42 | 2020 |
| A variant of a killer cell immunoglobulin-like receptor is associated with resistance to PD-1 blockade in lung cancer MP Trefny, SI Rothschild, F Uhlenbrock, D Rieder, B Kasenda, ... Clinical Cancer Research 25 (10), 3026-3034, 2019 | 41 | 2019 |
| Cancer immunology–development of novel anti-cancer therapies SI Rothschild, DS Thommen, W Moersig, P Müller, A Zippelius Swiss medical weekly 145 (0506), w14066-w14066, 2015 | 37 | 2015 |
| Expression of inhibitory receptors on intratumoral T cells modulates the activity of a T cell-bispecific antibody targeting folate receptor J Schreiner, DS Thommen, P Herzig, M Bacac, C Klein, A Roller, ... Oncoimmunology 5 (2), e1062969, 2016 | 36 | 2016 |
