Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche K Schepers, EM Pietras, D Reynaud, J Flach, M Binnewies, T Garg, ... Cell stem cell 13 (3), 285-299, 2013 | 689 | 2013 |
Normal and leukemic stem cell niches: insights and therapeutic opportunities K Schepers, TB Campbell, E Passegué Cell stem cell 16 (3), 254-267, 2015 | 485 | 2015 |
Invasive breast cancer reprograms early myeloid differentiation in the bone marrow to generate immunosuppressive neutrophils AJ Casbon, D Reynaud, C Park, E Khuc, DD Gan, K Schepers, ... Proceedings of the National Academy of Sciences 112 (6), E566-E575, 2015 | 446 | 2015 |
One naive T cell, multiple fates in CD8+ T cell differentiation C Gerlach, JW Van Heijst, E Swart, D Sie, N Armstrong, RM Kerkhoven, ... Journal of Experimental Medicine 207 (6), 1235-1246, 2010 | 299 | 2010 |
Tumor Rejection Induced by CD70-mediated Quantitative and Qualitative Effects on Effector CD8+ T Cell Formation R Arens, K Schepers, MA Nolte, MF van Oosterwijk, RAW van Lier, ... The Journal of experimental medicine 199 (11), 1595-1605, 2004 | 194 | 2004 |
Recruitment of antigen-specific CD8+ T cells in response to infection is markedly efficient JWJ van Heijst, C Gerlach, E Swart, D Sie, C Nunes-Alves, RM Kerkhoven, ... Science 325 (5945), 1265-1269, 2009 | 173 | 2009 |
JunB protects against myeloid malignancies by limiting hematopoietic stem cell proliferation and differentiation without affecting self-renewal M Santaguida, K Schepers, B King, AJ Sabnis, EC Forsberg, JL Attema, ... Cancer cell 15 (4), 341-352, 2009 | 165 | 2009 |
Dissecting T cell lineage relationships by cellular barcoding K Schepers, E Swart, JWJ van Heijst, C Gerlach, M Castrucci, D Sie, ... The Journal of experimental medicine 205 (10), 2309-2318, 2008 | 150 | 2008 |
Differential kinetics of antigen-specific CD4+ and CD8+ T cell responses in the regression of retrovirus-induced sarcomas K Schepers, M Toebes, G Sotthewes, FA Vyth-Dreese, TAM Dellemijn, ... The Journal of Immunology 169 (6), 3191-3199, 2002 | 109 | 2002 |
Mesenchymal stromal cells: a novel therapy for the treatment of chronic obstructive pulmonary disease? W Broekman, PPSJ Khedoe, K Schepers, H Roelofs, J Stolk, PS Hiemstra Thorax 73 (6), 565-574, 2018 | 101 | 2018 |
HIF signaling in osteoblast-lineage cells promotes systemic breast cancer growth and metastasis in mice CS Devignes, Y Aslan, A Brenot, A Devillers, K Schepers, S Fabre, ... Proceedings of the National Academy of Sciences 115 (5), E992-E1001, 2018 | 92 | 2018 |
Autophagy Proteins ATG5 and ATG7 Are Essential for the Maintenance of Human CD34+ Hematopoietic Stem-Progenitor Cells MC Gomez-Puerto, H Folkerts, ATJ Wierenga, K Schepers, JJ Schuringa, ... Stem Cells 34 (6), 1651-1663, 2016 | 89 | 2016 |
Activated Gs signaling in osteoblastic cells alters the hematopoietic stem cell niche in mice K Schepers, EC Hsiao, T Garg, MJ Scott, E Passegué Blood, The Journal of the American Society of Hematology 120 (17), 3425-3435, 2012 | 83 | 2012 |
Effective postexposure treatment of retrovirus-induced disease with immunostimulatory DNA containing CpG motifs ARM Olbrich, S Schimmer, K Heeg, K Schepers, TNM Schumacher, ... Journal of virology 76 (22), 11397-11404, 2002 | 75 | 2002 |
Generation of T cell help through a MHC class I-restricted TCR HWHG Kessels, K Schepers, MD van den Boom, DJ Topham, ... The Journal of Immunology 177 (2), 976-982, 2006 | 62 | 2006 |
CD4 memory T cells survive and proliferate but fail to differentiate in the absence of CD40 M MacLeod, MJ Kwakkenbos, A Crawford, S Brown, B Stockinger, ... The Journal of experimental medicine 203 (4), 897-906, 2006 | 60 | 2006 |
Independent roles of perforin, granzymes, and Fas in the control of Friend retrovirus infection G Zelinskyy, S Balkow, S Schimmer, K Schepers, MM Simon, U Dittmer Virology 330 (2), 365-374, 2004 | 60 | 2004 |
Temporal effects of gamma interferon deficiency on the course of Friend retrovirus infection in mice IM Stromnes, U Dittmer, TNM Schumacher, K Schepers, RJ Messer, ... Journal of virology 76 (5), 2225-2232, 2002 | 50 | 2002 |
The impact of immune response on endochondral bone regeneration A Longoni, L Knežević, K Schepers, H Weinans, A Rosenberg, D Gawlitta NPJ Regenerative medicine 3 (1), 22, 2018 | 47 | 2018 |
Preparing for cell culture scale-out: establishing parity of bioreactor-and flask-expanded mesenchymal stromal cell cultures R Das, R Roosloot, M van Pel, K Schepers, M Driessen, WE Fibbe, ... Journal of translational medicine 17, 1-13, 2019 | 42 | 2019 |