| Usefulness of Caco-2/HT29-MTX and Caco-2/HT29-MTX/Raji B coculture models to predict intestinal and colonic permeability compared to Caco-2 monoculture I Lozoya-Agullo, F Araujo, I Gonzalez-Alvarez, M Merino-Sanjuan, ... Molecular pharmaceutics 14 (4), 1264-1270, 2017 | 156 | 2017 |
| Design, characterization and in vitro evaluation of 5-aminosalicylic acid loaded N-succinyl-chitosan microparticles for colon specific delivery C Mura, A Nácher, V Merino, M Merino-Sanjuán, M Manconi, G Loy, ... Colloids and Surfaces B: Biointerfaces 94, 199-205, 2012 | 94 | 2012 |
| Chitosan–xanthan gum microparticle-based oral tablet for colon-targeted and sustained delivery of quercetin C Caddeo, A Nácher, O Díez-Sales, M Merino-Sanjuán, AM Fadda, ... Journal of microencapsulation 31 (7), 694-699, 2014 | 85 | 2014 |
| In-situ intestinal rat perfusions for human Fabs prediction and BCS permeability class determination: Investigation of the single-pass vs. the Doluisio experimental approaches I Lozoya-Agullo, M Zur, O Wolk, A Beig, I González-Álvarez, ... International journal of pharmaceutics 480 (1-2), 1-7, 2015 | 80 | 2015 |
| N-Succinyl-chitosan systems for 5-aminosalicylic acid colon delivery: in vivo study with TNBS-induced colitis model in rats C Mura, A Nácher, V Merino, M Merino-Sanjuan, C Carda, A Ruiz, ... International journal of pharmaceutics 416 (1), 145-154, 2011 | 78 | 2011 |
| In situ perfusion model in rat colon for drug absorption studies: Comparison with small intestine and Caco-2 cell model I Lozoya-Agullo, I González-Álvarez, M González-Álvarez, ... Journal of pharmaceutical sciences 104 (9), 3136-3145, 2015 | 72 | 2015 |
| Improving oral bioavailability and pharmacokinetics of liposomal metformin by glycerolphosphate–chitosan microcomplexation M Manconi, A Nácher, V Merino, M Merino-Sanjuan, ML Manca, C Mura, ... Aaps Pharmscitech 14, 485-496, 2013 | 62 | 2013 |
| Segmental-dependent permeability throughout the small intestine following oral drug administration: Single-pass vs. Doluisio approach to in-situ rat perfusion I Lozoya-Agullo, M Zur, A Beig, N Fine, Y Cohen, M González-Álvarez, ... International journal of pharmaceutics 515 (1-2), 201-208, 2016 | 56 | 2016 |
| Enzyme‐responsive silica mesoporous supports capped with azopyridinium salts for controlled delivery applications N Mas, A Agostini, L Mondragon, A Bernardos, F Sancenon, MD Marcos, ... Chemistry–A European Journal 19 (4), 1346-1356, 2013 | 48 | 2013 |
| Antibiotic‐loaded bone cement as prophylaxis in total joint replacement J Martínez‐Moreno, V Merino, A Nácher, JL Rodrigo, M Climente, ... Orthopaedic surgery 9 (4), 331-341, 2017 | 46 | 2017 |
| Hydroxypropylmethylcellulose films for the ophthalmic delivery of diclofenac sodium S El-Sousi, A Nácher, C Mura, A Catalán-Latorre, V Merino, ... Journal of Pharmacy and Pharmacology 65 (2), 193-200, 2013 | 42 | 2013 |
| In vitro–in vivo correlations: general concepts, methodologies and regulatory applications I González-García, V Mangas-Sanjuán, M Merino-Sanjuán, M Bermejo Drug development and industrial pharmacy 41 (12), 1935-1947, 2015 | 40 | 2015 |
| Intestinal transport of cefuroxime axetil in rats: absorption and hydrolysis processes N Ruiz-Balaguer, A Nacher, VG Casabo, MM Sanjuan International journal of pharmaceutics 234 (1-2), 101-111, 2002 | 40 | 2002 |
| Pharmacokinetic models for the saturable absorption of cefuroxime axetil and saturable elimination of cefuroxime P Ruiz-Carretero, M Merino-Sanjuan, A Nacher, VG Casabo European journal of pharmaceutical sciences 21 (2-3), 217-223, 2004 | 39 | 2004 |
| Investigating drug absorption from the colon: Single-pass vs. Doluisio approaches to in-situ rat large-intestinal perfusion I Lozoya-Agullo, M Zur, N Fine-Shamir, M Markovic, Y Cohen, D Porat, ... International journal of pharmaceutics 527 (1-2), 135-141, 2017 | 34 | 2017 |
| Relevance of multidrug resistance proteins on the clinical efficacy of cancer therapy V Merino, NV Jimenez-Torres, M Merino-Sanjuan Current drug delivery 1 (3), 203-212, 2004 | 32 | 2004 |
| PLGA nanoparticles are effective to control the colonic release and absorption on ibuprofen I Lozoya-Agullo, F Araújo, I González-Álvarez, M Merino-Sanjuán, ... European Journal of Pharmaceutical Sciences 115, 119-125, 2018 | 31 | 2018 |
| Closed-loop doluisio (colon, small intestine) and single-pass intestinal perfusion (colon, jejunum) in rat—biophysical model and predictions based on Caco-2 I Lozoya-Agullo, I Gonzalez-Alvarez, M Zur, N Fine-Shamir, Y Cohen, ... Pharmaceutical Research 35, 1-23, 2018 | 31 | 2018 |
| Multi-output model with Box–Jenkins operators of linear indices to predict multi-target inhibitors of ubiquitin–proteasome pathway GM Casañola-Martin, H Le-Thi-Thu, F Pérez-Giménez, Y Marrero-Ponce, ... Molecular Diversity 19, 347-356, 2015 | 30 | 2015 |
| Transdermal nortriptyline hydrocloride patch formulated within a chitosan matrix intended to be used for smoking cessation JJ Escobar-Chávez, V Merino, O Díez-Sales, A Nácher-Alonso, ... Pharmaceutical development and technology 16 (2), 162-169, 2011 | 27 | 2011 |
