Artículos añadidos en el último año, ordenados por fecha

[HTML][HTML] MdMYB8 is associated with flavonol biosynthesis via the activation of the MdFLS promoter in the fruits of Malus crabapple

H Li, Y Li, J Yu, T Wu, J Zhang, J Tian, Y Yao - Horticulture Research, 2020 - nature.com
hace 4 días - Flavonols are polyphenolic compounds that play important roles in plant
stress resistance and development. They are also valuable components of the human diet.
The Malus crabapple cultivar 'Flame'provides an excellent model for studying flavonol …

[HTML][HTML] A Nicotiana benthamiana AP2/ERF transcription factor confers resistance to Phytophthora parasitica

J Yu, C Chai, G Ai, Y Jia, W Liu, X Zhang, T Bai… - Phytopathology …, 2020 - Springer
hace 4 días - Diseases caused by Phytophthora species seriously affect global crop
production and food security. Identification of key factors involved in plant resistance is
valuable for disease management. Previously, we characterized the transcriptome of …

[HTML][HTML] A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism

M Pradas-Juni, NR Hansmeier, JC Link… - Nature …, 2020 - nature.com
hace 5 días - Obesity and type 2 diabetes mellitus are global emergencies and long
noncoding RNAs (lncRNAs) are regulatory transcripts with elusive functions in metabolism.
Here we show that a high fraction of lncRNAs, but not protein-coding mRNAs, are repressed …

[HTML][HTML] Trypanosomatid parasite dynamically changes the transcriptome during infection and modifies honey bee physiology

Q Liu, J Lei, AC Darby, T Kadowaki - Communications Biology, 2020 - nature.com
hace 5 días - It is still not understood how honey bee parasite changes the gene expression
to adapt to the host environment and how the host simultaneously responds to the parasite
infection by modifying its own gene expression. To address this question, we studied a …

Single-Cell Transcriptomic Atlas of Primate Ovarian Aging

S Wang, Y Zheng, J Li, Y Yu, W Zhang, M Song, Z Liu… - Cell, 2020 - Elsevier
hace 5 días - Molecular mechanisms of ovarian aging and female age-related fertility
decline remain unclear. We surveyed the single-cell transcriptomic landscape of ovaries
from young and aged non-human primates (NHPs) and identified seven ovarian cell types …

[PDF][PDF] JP regression v28 continued [version 1; peer review: awaiting peer

J Brown - 2019 - stage.f1000research.com
hace 5 días - The mouse ENCODE Consortium has collected multiple types of genomic and
functional data in order to better understand the potential utility of the mouse as a model
system for biomedical research. To study gene expression levels, the Consortium collected …

[PDF][PDF] JP reg v28 editorial [version 1; peer review: not peer reviewed]

J Brown - 2019 - stage.f1000research.com
hace 5 días - The mouse ENCODE Consortium has collected multiple types of genomic and
functional data in order to better understand the potential utility of the mouse as a model
system for biomedical research. To study gene expression levels, the Consortium collected …

[HTML][HTML] Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties

Y Terashima, E Toda, M Itakura, M Otsuji… - Nature …, 2020 - nature.com
hace 6 días - Tumor-associated macrophages affect tumor progression and resistance to
immune checkpoint therapy. Here, we identify the chemokine signal regulator FROUNT as a
target to control tumor-associated macrophages. The low level FROUNT expression in …

Remethylation of Dnmt3a−/− hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing

S Ketkar, AM Verdoni, AM Smith… - Proceedings of the …, 2020 - National Acad Sciences
hace 6 días - Mutations in the DNA methyltransferase 3A (DNMT3A) gene are the most
common cause of age-related clonal hematopoiesis (ARCH) in older individuals, and are
among the most common initiating events for acute myeloid leukemia (AML). The most …

Identification and differential expression analysis of anthocyanin biosynthetic genes in root-skin color variants of radish (Raphanus sativus L.)

R Yu, X Du, J Li, L Liu, C Hu, X Yan, Y Xia, H Xu - Genes & Genomics - Springer
hace 6 días - Background Taproot skin color is a major trait for assessing the commercial
and nutritional quality of radish, and red-skinned radish is confirmed to improve consumer's
interest and health. However, little is known about the molecular mechanisms responsible …